• Issue

    Journal of Biomedical Materials Research Part A: Volume 113, Issue 5

    May 2025

ISSUE INFORMATION

Free Access

Issue Information

  • First Published: 21 April 2025

RESEARCH ARTICLE

Harnessing Thrombospondin-1-Enabled Decellularized Nucleus Pulposus Matrices and Elastin-Like Recombinamers to Rebuild an Avascular Analogue of the Intervertebral Disc

  • First Published: 23 April 2025
Harnessing Thrombospondin-1-Enabled Decellularized Nucleus Pulposus Matrices and Elastin-Like Recombinamers to Rebuild an Avascular Analogue of the Intervertebral Disc

Decellularized nucleus pulposus isolated from young bovine tails were processed into physical hydrogels to rebuild an avascular analogue of the intervertebral disc. The materials were supplemented with thrombospondin-1 to emulate the anti-angiogenic character of the native tissue. Elastin-like recombinamers were used to increase the bulk mechanical properties. The final constructs were characterized by their composition, structure, physical and rheological behavior, and cytocompatibility.

RESEARCH ARTICLE

Electrospun Decellularized Skeletal Muscle Tissue/Polycaprolactone/Polyaniline as a Potential Scaffold for Muscle Tissue Engineering

  • First Published: 28 April 2025
Electrospun Decellularized Skeletal Muscle Tissue/Polycaprolactone/Polyaniline as a Potential Scaffold for Muscle Tissue Engineering

Electrospun decellularized skeletal muscle tissue/polycaprolactone/polyaniline can be considered as a potential skeletal muscle tissue engineering scaffold because of its suitable microstructure, high biocompatibility, and promotive effects on cell elongation and myogenesis markers expression.

Versatile Coating via Programmed Assembly of miR-155 Inhibitor and Endothelial Affinity Peptide

  • First Published: 11 May 2025
Versatile Coating via Programmed Assembly of miR-155 Inhibitor and Endothelial Affinity Peptide

NiTi alloy surface (NPMR) coated with heparin, anti-miR155, and REDV was prepared systematically through the robust adhesiveness of dopamine and click chemistry methodologies. With its simple and efficient preparation process and excellent performance, this versatile coating effectively reduced the risks of poor endothelialization and inflammatory response commonly associated with NiTi alloy as an implantable medical material.

Open Access

Bilayer Electrospun Polyurethane Membrane With Tunable Elastomeric Properties for the Treatment of Congenital Diaphragmatic Hernia

  • First Published: 11 May 2025
Bilayer Electrospun Polyurethane Membrane With Tunable Elastomeric Properties for the Treatment of Congenital Diaphragmatic Hernia

  • Bilayer film/fiber membranes were produced in a continuous electrospinning process.
  • Membranes withstand repetitive inflation cycles at pressures similar to breathing.
  • Membranes promote cellular colonization without pro-inflammatory effects.