• Issue

    Journal of Thrombosis and Haemostasis: Volume 18, Issue 1

    1-268
    January 2020
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ISSUE INFORMATION

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Issue Information

  • Pages: 1-4
  • First Published: 02 January 2020

EDITORIAL

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Changes

David Lillicrap,  James H. Morrissey, 
  • Page: 1
  • First Published: 02 January 2020

WHAT THE NEIGHBORS SAY

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What the neighbors say

  • Page: 2
  • First Published: 02 January 2020

NEIGHBORHOOD WATCH

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Inflammaging and platelet hyperreactivity: A new therapeutic target?

Joshua Price,  Janet M. Lord,  Paul Harrison, 
  • Pages: 3-5
  • First Published: 02 January 2020

REVIEW ARTICLE

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Molecular basis of protease-activated receptor 1 signaling diversity

Orla Willis Fox,  Roger J. S. Preston, 
  • Pages: 6-16
  • First Published: 24 September 2019

ISTH GUIDANCE AND GUIDELINES

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Recommendations for clinical laboratory testing for antithrombin deficiency; Communication from the SSC of the ISTH

Elizabeth M. Van Cott,  Christelle Orlando,  Gary W. Moore,  Peter C. Cooper,  Piet Meijer,  Richard Marlar,  for the Subcommittee on Plasma Coagulation Inhibitors , 
  • Pages: 17-22
  • First Published: 26 September 2019

HAEMOSTASIS

Original Articles

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Effects of vorapaxar on clot characteristics, coagulation, inflammation, and platelet and endothelial function in patients treated with mono- and dual-antiplatelet therapy

Kevin Bliden,  Rahul Chaudhary,  Athan Kuliopulos,  Henry Tran,  Hamid Taheri,  Behnam Tehrani,  Arnold Rosenblatt,  Eliano Navarese,  Udaya S. Tantry,  Paul A. Gurbel, 
  • Pages: 23-35
  • First Published: 24 August 2019
Open Access

Cross-reacting inhibitors against recombinant porcine factor VIII in acquired hemophilia A: Data from the GTH-AH 01/2010 Study

Halet Türkantoz,  Christoph Königs,  Paul Knöbl,  Robert Klamroth,  Katharina Holstein,  Angela Huth-Kühne,  Jürgen Heinz,  Hermann Eichler,  Andreas Tiede, 
  • Pages: 36-43
  • First Published: 26 August 2019
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P2X1 ion channel deficiency causes massive bleeding in inflamed intestine and increases thrombosis

Odile Wéra,  Christelle Lecut,  Laurence Servais,  Alexandre Hego,  Céline Delierneux,  Zheshen Jiang,  Aurore Keutgens,  Richard J. Evans,  Philippe Delvenne,  Patrizio Lancellotti,  Cécile Oury, 
  • Pages: 44-56
  • First Published: 26 August 2019
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The 3.2 Å structure of a bioengineered variant of blood coagulation factor VIII indicates two conformations of the C2 domain

Ian W. Smith,  Anne E. d'Aquino,  Christopher W. Coyle,  Andrew Fedanov,  Ernest T. Parker,  Gabriela Denning,  Harold Trent Spencer,  Pete Lollar,  Christopher B. Doering,  Paul Clint Spiegel Jr., 
  • Pages: 57-69
  • First Published: 27 August 2019
Open Access

Effect of multidose drug dispensing on the time in therapeutic range in patients using vitamin-K antagonists: A randomized controlled trial

Bram J. Mertens,  Henk-Frans Kwint,  Svetlana V. Belitser,  Felix J. M. van der Meer,  Rob J. van Marum,  Marcel L. Bouvy, 
  • Pages: 70-78
  • First Published: 30 August 2019
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Glycosylation sterically inhibits platelet adhesion to von Willebrand factor without altering intrinsic conformational dynamics

Alexander Tischer,  Venkata R. Machha,  Laurie Moon-Tasson,  Linda M. Benson,  Matthew Auton, 
  • Pages: 79-90
  • First Published: 03 September 2019
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Cell type-specific mechanisms coupling protease-activated receptor-1 to infectious colitis pathogenesis

Alexander A. Boucher,  Leah Rosenfeldt,  Duaa Mureb,  Jessica Shafer,  Bal Krishan Sharma,  Adam Lane,  Rebecca R. Crowther,  Melanie C. McKell,  Jordan Whitt,  Theresa Alenghat,  Joseph Qualls,  Silvio Antoniak,  Nigel Mackman,  Matthew J. Flick,  Kris A. Steinbrecher,  Joseph S. Palumbo, 
  • Pages: 91-103
  • First Published: 20 September 2019
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Enhanced potency of recombinant factor VIIa with increased affinity to activated platelets

Mari Enoksson,  Erika J. Martin,  Heidi Holmberg,  Mette S. Jensen,  Mads Kjelgaard-Hansen,  Thomas Egebjerg,  Jens Buchardt,  Thomas N. Krogh,  Helle Demuth,  Annika Sanfridson,  Ida Hilden,  Marianne Kjalke,  Donald F. Brophy, 
  • Pages: 104-113
  • First Published: 23 September 2019
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A multicenter study of anticoagulation in operable chronic thromboembolic pulmonary hypertension

Katherine Bunclark,  Michael Newnham,  Yi-Da Chiu,  Alessandro Ruggiero,  Sofia S. Villar,  John E. Cannon,  Gerry Coghlan,  Paul A. Corris,  Luke Howard,  David Jenkins,  Martin Johnson,  David G. Kiely,  Choo Ng,  Nicholas Screaton,  Karen Sheares,  Dolores Taboada,  Steven Tsui,  Stephen John Wort,  Joanna Pepke-Zaba,  Mark Toshner, 
  • Pages: 114-122
  • First Published: 26 September 2019
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Role of thrombomodulin expression on hematopoietic stem cells

Sreemanti Basu,  Hai Po Helena Liang,  Irene Hernandez,  Mark Zogg,  British Fields,  Jennifer May,  Yamini Ogoti,  Tine Wyseure,  Laurent O. Mosnier,  Robert T. Burns,  Karen Carlson,  Hartmut Weiler, 
  • Pages: 123-135
  • First Published: 19 October 2019

THROMBOSIS

Original Articles

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Partial rescue of naturally occurring active site factor X variants through decreased inhibition by tissue factor pathway inhibitor and antithrombin

Josefin Ahnström,  Magdalena Gierula,  Joseph Temenu,  Michael A. Laffan,  David A. Lane, 
  • Pages: 136-150
  • First Published: 29 August 2019
Open Access

Sex-specific differences in chronic thromboembolic pulmonary hypertension. Results from the European CTEPH registry

Stefano Barco,  Frederikus A. Klok,  Stavros V. Konstantinides,  Philippe Dartevelle,  Elie Fadel,  David Jenkins,  Nick H. Kim,  Michael Madani,  Hiromi Matsubara,  Eckhard Mayer,  Joanna Pepke-Zaba,  Gérald Simonneau,  Marion Delcroix,  Irene M. Lang, 
  • Pages: 151-161
  • First Published: 03 September 2019
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Venous thromboembolism in breast cancer patients receiving cyclin-dependent kinase inhibitors

Lorenzo Gervaso,  Alberto J. Montero,  Xuefei Jia,  Alok A. Khorana, 
  • Pages: 162-168
  • First Published: 03 September 2019
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The (non-)sense of detecting anti-cardiolipin and anti-β2glycoprotein I IgM antibodies in the antiphospholipid syndrome

Walid Chayoua,  Hilde Kelchtermans,  Jean-Christophe Gris,  Gary W. Moore,  Jacek Musiał,  Denis Wahl,  Philip G. de Groot,  Bas de Laat,  Katrien M. J. Devreese, 
  • Pages: 169-179
  • First Published: 13 September 2019
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Fondaparinux pentasaccharide reduces sepsis coagulopathy and promotes survival in the baboon model of Escherichia coli sepsis

Ravi S. Keshari,  Robert Silasi,  Narcis I. Popescu,  Constantin Georgescu,  Hala Chaaban,  Cristina Lupu,  Owen J. T. McCarty,  Charles T. Esmon,  Florea Lupu, 
  • Pages: 180-190
  • First Published: 24 September 2019
Open Access

Novel inhibitor ZED3197 as potential drug candidate in anticoagulation targeting coagulation FXIIIa (F13a)

Ralf Pasternack,  Christian Büchold,  Robert Jähnig,  Christiane Pelzer,  Michael Sommer,  Andreas Heil,  Peter Florian,  Götz Nowak,  Uwe Gerlach,  Martin Hils, 
  • Pages: 191-200
  • First Published: 02 October 2019
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Quantitative HLA-class-II/factor VIII (FVIII) peptidomic variation in dendritic cells correlates with the immunogenic potential of therapeutic FVIII proteins in hemophilia A

Vincent P. Diego,  Bernadette W. Luu,  Marco Hofmann,  Long V. Dinh,  Marcio Almeida,  Jerry S. Powell,  Raja Rajalingam,  Juan M. Peralta,  Satish Kumar,  Joanne E. Curran,  Zuben E. Sauna,  Roberta Kellerman,  Yara Park,  Nigel S. Key,  Miguel A. Escobar,  Huy Huynh,  Anne M. Verhagen,  Sarah Williams-Blangero,  Paul V. Lehmann,  Eugene Maraskovsky,  John Blangero,  Tom E. Howard, 
  • Pages: 201-216
  • First Published: 25 September 2019

BRIEF REPORT

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Screening pulmonary angiogram and the effect on anticoagulation strategies in severe respiratory failure patients on venovenous extracorporeal membrane oxygenation

Emma L. Hartley,  Neeraj Singh,  Nicholas Barrett,  Duncan Wyncoll,  Andrew Retter, 
  • Pages: 217-221
  • First Published: 20 September 2019

PLATELETS

Original Articles

Open Access

Phagocytosis by endothelial cells inhibits procoagulant activity of platelets of essential thrombocythemia in vitro

Shuting Ji,  Weijun Dong,  Yushan Qi,  Hong Gao,  Danwei Zhao,  Minghui Xu,  Tingting Li,  Hongyin Yu,  Yuting Sun,  Ruishuang Ma,  Jialan Shi,  Chunyan Gao, 
  • Pages: 222-233
  • First Published: 23 August 2019
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Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease

Dominik Rath,  Saskia von Ungern-Sternberg,  David Heinzmann,  Manuel Sigle,  Mona Monzien,  Katja Horstmann,  Elke Schaeffeler,  Stefan Winter,  Karin Müller,  Patrick Groga-Bada,  Monika Zdanyte,  Oliver Borst,  Alma Zernecke,  Meinrad Gawaz,  Peter Martus,  Matthias Schwab,  Tobias Geisler,  Peter Seizer, 
  • Pages: 234-242
  • First Published: 13 September 2019

VASCULAR BIOLOGY

Original Article

Open Access

Human endothelial cells size-select their secretory granules for exocytosis to modulate their functional output

Jessica J. McCormack,  Kimberly J. Harrison-Lavoie,  Daniel F. Cutler, 
  • Pages: 243-254
  • First Published: 13 September 2019

ISTH SSC COMMUNICATION

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A new WHO reference reagent for activated blood coagulation factor X (FXa), human (15/102)

Craig Thelwell,  John Hogwood,  Sarah Daniels,  Peter Rigsby, 
  • Pages: 255-257
  • First Published: 28 August 2019

LETTERS TO THE EDITOR

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Serologically predicting direct oral anticoagulant failure with antiphospholipid antibodies

Marvin Kajy,  Randy Lieberman,  Preeti Ramappa, 
  • Pages: 258-259
  • First Published: 02 January 2020
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Use of direct oral anticoagulants in antiphospholipid syndrome: Reply

Hannah Cohen,  Maria Efthymiou,  David A. Isenberg, 
  • Pages: 259-261
  • First Published: 02 January 2020

OBITUARIES

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Paul E. Bock, PhD (21 October, 1949–11 October, 2019)

Steven T. Olson,  Dudley K. Strickland, 
  • Pages: 262-263
  • First Published: 02 January 2020
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Professor Russell F. Doolittle (1931-2019)

Mattia Rocco,  John W. Weisel,  Moniek de Maat, 
  • Pages: 264-266
  • First Published: 02 January 2020

ANNOUNCEMENTS

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ISTH News and Updates: Join the ISTH Today – Student Membership is Now Free!

  • Pages: 267-268
  • First Published: 02 January 2020