Epilepsia: Vol 66, No 3

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Epilepsia

Epilepsia Open

Epileptic Disorders

2025 ILAE Article Award Winners

Basic Science Research: Louison Pineau, PhD,
Pathogenic MTOR somatic variant causing focal cortical dysplasia drives hyperexcitability via overactivation of neuronal GluN2C N-methyl-D-aspartate receptors

An interview with Louison Pineau, 2025 Epilepsia Prize winner for basic science

Clinical Research: Tobias Bauer MD,
Proof of concept: Portable ultra-low-field magnetic resonance imaging for the diagnosis of epileptogenic brain pathologies

An interview with Tobias Bauer, 2025 Epilepsia Prize winner for clinical research

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Epilepsia: Volume 66, Issue 3

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ISSUE INFORMATION

Issue Information

CRITICAL REVIEW

Fast activity chirp patterns in focal seizures from patients and animal models

RESEARCH ARTICLE

A new perspective on drug-resistant epilepsy in children with focal cortical dysplasia type 1: From challenge to favorable outcome

Evolution in the prescription and cost of non-intravenous rescue benzodiazepines for the treatment of seizure emergencies

Lateralizing value of interictal epileptiform discharges and other parameters in hypothalamic hamartoma

Can the large language model ChatGPT-4omni predict outcomes in adult patients with status epilepticus?

Bridging the conversational gap in epilepsy: Using large language models to reveal insights into patient behavior and concerns from online discussions

Unsupervised clustering of a deeply phenotyped cohort of adults with idiopathic generalized epilepsy

Epilepsy and employment: A qualitative interview study with heads of human resources and occupational physicians in Austria — A call for legislative optimization according to the WHO Intersectoral Global Action Plan

Community-onset pediatric status epilepticus: Barriers to care and outcomes in a real-world setting

Community-based epilepsy care in an onchocerciasis-endemic area: A 3-year cohort study in Mahenge, Tanzania

Prognostic factors and impact of management strategies for status epilepticus: The STEPPER study in the Emilia-Romagna region, Italy

Analysis of participant race and sex reporting and disparities in US epilepsy clinical trials

Incidence of childhood and youth epilepsy: A population-based prospective cohort study utilizing current International League Against Epilepsy classifications for seizures, syndromes, and etiologies

Neuronal complexity tracks changes of epileptic activity and identifies epilepsy patients independent of interictal epileptiform discharges

Cortical hemodynamics of electrographic status epilepticus in the critically ill

Elevated Astrocytic NFAT5 of the hippocampus increases epilepsy susceptibility in hypoxic-ischemic mice

Diffusion imaging shows microstructural alterations in untreated, non-lesional patients already after a first unprovoked seizure

Anatomical categorization of insulo-opercular focal cortical dysplasia and the spatial patterns of stereoelectroencephalography

Phenotypic traits and family history in patients with 22q11.2 deletion syndrome and generalized epilepsy: A multicenter case–control study

Plasma microRNAs as prognostic biomarkers for development of severe epilepsy after experimental traumatic brain injury—EpiBioS4Rx Project 1 study

Forty-hertz sensory entrainment impedes kindling epileptogenesis and reduces amyloid pathology in an Alzheimer disease mouse model

Progressive central cardiorespiratory rate downregulation and intensifying epilepsy lead to sudden unexpected death in epilepsy in mouse model of the most common human ATP1A3 mutation

Rare dysfunctional SCN2A variants are associated with malformation of cortical development

Preferential superficial cortical layer activation during seizure propagation

GRAY MATTER

ANNOUNCEMENT

Epilepsia – March 2025 Announcements

BRIEF COMMUNICATION

Age-associated differences in FIRES: Characterizing prodromal presentation and long-term outcomes via the web-based NORSE/FIRES Family Registry

Sex-based analysis of status epilepticus management and outcome: A cohort study

Tremor as an intrinsic feature of juvenile myoclonic epilepsy