• Issue

    Hepatology: Volume 42, Issue 5

    985-1238
    November 2005
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Hepatology Highlights

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Hepatology highlights†

Neil Kaplowitz, 
  • Pages: 985-986
  • First Published: 25 October 2005

Concise Review in Mechanisms of Disease

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Insulin resistance: A metabolic pathway to chronic liver disease†

Elisabetta Bugianesi,  Arthur J. McCullough,  Giulio Marchesini, 
  • Pages: 987-1000
  • First Published: 25 October 2005

Editorial

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Trimming the fat from liver regeneration†‡

David A. Rudnick, 
  • Pages: 1001-1003
  • First Published: 25 October 2005
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The CAR nuclear receptor and hepatocyte proliferation†‡

Robert H. Costa,  Vladimir V. Kalinchenko,  Yongjun Tan,  I-Ching Wang, 
  • Pages: 1004-1008
  • First Published: 25 October 2005
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Reflections on therapeutic trials in primary biliary cirrhosis†‡

Combes Burton M.D., 
  • Page: 1009
  • First Published: 25 October 2005

Viral Hepatitis

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Interferon alfa-2b in combination with ribavirin for the treatment of chronic hepatitis C in children: Efficacy, safety, and pharmacokinetics†

Regino P. González-Peralta,  Deirdre A. Kelly,  Barbara Haber,  Jean Molleston,  Karen F. Murray,  Maureen M. Jonas,  Mark Shelton,  Giorgina Mieli-Vergani,  Yoav Lurie,  Steven Martin,  Thomas Lang,  Andrew Baczkowski,  Michael Geffner,  Samir Gupta,  Mark Laughlin,  for the International Pediatric Hepatitis C Therapy Group , 
  • Pages: 1010-1018
  • First Published: 25 October 2005
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HCV-associated B cell clonalities in the liver do not carry the t(14;18) chromosomal translocation †

Domenico Sansonno,  Felicia Anna Tucci,  Valli De Re,  Gianfranco Lauletta,  Michele Montrone,  Massimo Libra,  Franco Dammacco, 
  • Pages: 1019-1027
  • First Published: 25 October 2005
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Lamivudine plus interleukin-12 combination therapy in chronic hepatitis B: Antiviral and immunological activity†

Eirini I. Rigopoulou,  Deepak Suri,  Shilpa Chokshi,  Ivana Mullerova,  Steven Rice,  Richard S. Tedder,  Roger Williams,  Nikolai V. Naoumov, 
  • Pages: 1028-1036
  • First Published: 25 October 2005
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Mannose-binding lectin in chronic hepatitis B virus infection†

Wai Po Chong,  Yuk Fai To,  Wai Kee Ip,  Man Fung Yuen,  Tung Ping Poon,  Wilfred H.S. Wong,  Ching Lung Lai,  Yu Lung Lau, 
  • Pages: 1037-1045
  • First Published: 25 October 2005
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Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus†

Masataka Tsuge,  Nobuhiko Hiraga,  Hideki Takaishi,  Chiemi Noguchi,  Hiromi Oga,  Michio Imamura,  Shoichi Takahashi,  Eiji Iwao,  Yoshifumi Fujimoto,  Hidenori Ochi,  Kazuaki Chayama,  Chise Tateno,  Katsutoshi Yoshizato, 
  • Pages: 1046-1054
  • First Published: 25 October 2005
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Human monoclonal antibodies that react with the E2 glycoprotein of hepatitis C virus and possess neutralizing activity†

Darren J. Schofield,  Birke Bartosch,  Yohko K. Shimizu,  Tobias Allander,  Harvey J. Alter,  Suzanne U. Emerson,  François-Loïc Cosset,  Robert H. Purcell, 
  • Pages: 1055-1062
  • First Published: 25 October 2005

Liver Biology and Pathobiology

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Early intrahepatic antigen-specific retention of naïve CD8+ T cells is predominantly ICAM-1/LFA-1 dependent in mice†

Patrick Bertolino,  Arnhild Schrage,  David G. Bowen,  Katja Klugewitz,  Saeed Ghani,  Katharina Eulenburg,  Lauren Holz,  Nancy Hogg,  Geoffrey W. McCaughan,  Alf Hamann, 
  • Pages: 1063-1071
  • First Published: 25 October 2005
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Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment in the rat†

Daniel Benten,  Vinay Kumaran,  Brigid Joseph,  Jörn Schattenberg,  Yury Popov,  Detlef Schuppan,  Sanjeev Gupta, 
  • Pages: 1072-1081
  • First Published: 25 October 2005
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Lack of gp130 expression results in more bacterial infection and higher mortality during chronic cholestasis in mice†

Torsten Wuestefeld,  Christian Klein,  Konrad L. Streetz,  Naiara Beraza,  Jürgen Schölmerich,  Lawrence J. Burgart,  Lars Zender,  Stefan Kubicka,  Gregory J. Gores,  Michael P. Manns,  Christian Trautwein, 
  • Pages: 1082-1090
  • First Published: 25 October 2005
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Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene†‡

José E. Manautou,  Dirk R. de Waart,  Cindy Kunne,  Noam Zelcer,  Michael Goedken,  Piet Borst,  Ronald Oude Elferink, 
  • Pages: 1091-1098
  • First Published: 25 October 2005
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Transcriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice†

Hongtao Wang,  Bhupinder P.S. Vohra,  Yan Zhang,  Robert O. Heuckeroth, 
  • Pages: 1099-1108
  • First Published: 25 October 2005
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Ethanol metabolism alters interferon gamma signaling in recombinant HepG2 cells†

Natalia A. Osna,  Dahn L. Clemens,  Terrence M. Donohue Jr., 
  • Pages: 1109-1117
  • First Published: 25 October 2005
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Gadd45β is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia† ‡

Amedeo Columbano,  Giovanna M. Ledda-Columbano,  Monica Pibiri,  Costanza Cossu,  Marta Menegazzi,  David D. Moore,  Wendong Huang,  Jianmin Tian,  Joseph Locker, 
  • Pages: 1118-1126
  • First Published: 25 October 2005
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Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma†

Meta W. Djojosubroto,  Allison C. Chin,  Ning Go,  Sonja Schaetzlein,  Michael P. Manns,  Sergei Gryaznov,  Calvin B. Harley,  K. Lenhard Rudolph, 
  • Pages: 1127-1136
  • First Published: 25 October 2005
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Temporal correlation of pathology and DNA damage with gene expression in a choline-deficient model of rat liver injury†

Christine L. Powell,  Oksana Kosyk,  Blair U. Bradford,  Joel S. Parker,  Edward K. Lobenhofer,  Ayumi Denda,  Fumiyuki Uematsu,  Dai Nakae,  Ivan Rusyn, 
  • Pages: 1137-1147
  • First Published: 25 October 2005
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A high-fat diet impairs liver regeneration in C57BL/6 mice through overexpression of the NF-κB inhibitor, IκBα† ‡

Robert A. DeAngelis,  Maciej M. Markiewski,  Rebecca Taub,  John D. Lambris, 
  • Pages: 1148-1157
  • First Published: 25 October 2005

Liver Failure and Liver Disease

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High prevalence of spontaneous portal-systemic shunts in persistent hepatic encephalopathy: A case-control study†

Oliviero Riggio,  Cesare Efrati,  Carlo Catalano,  Federica Pediconi,  Oriano Mecarelli,  Neri Accornero,  Francesca Nicolao,  Stefania Angeloni,  Andrea Masini,  Lorenzo Ridola,  Adolfo F. Attili,  Manuela Merli, 
  • Pages: 1158-1165
  • First Published: 25 October 2005
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Hepatic expression of ABC transporters G5 and G8 does not correlate with biliary cholesterol secretion in liver transplant patients†

Erwin Geuken,  Dorien S. Visser,  Henri G.D. Leuvenink,  Koert P. de Jong,  Paul M.J.G. Peeters,  Maarten J.H. Slooff,  Folkert Kuipers,  Robert J. Porte, 
  • Pages: 1166-1174
  • First Published: 25 October 2005
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Adipokines in NASH: Postprandial lipid metabolism as a link between adiponectin and liver disease†

Giovanni Musso,  Roberto Gambino,  Marilena Durazzo,  Giampaolo Biroli,  Monica Carello,  Emanuela Fagà,  Giovanni Pacini,  Franco De Michieli,  Laura Rabbione,  Alberto Premoli,  Maurizio Cassader,  Gianfranco Pagano, 
  • Pages: 1175-1183
  • First Published: 25 October 2005
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Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis† ‡

Burton Combes,  Scott S. Emerson,  Nancy L. Flye,  Santiago J. Munoz,  Velimir A. Luketic,  Marlyn J. Mayo,  Timothy M. McCashland,  Rowen K. Zetterman,  Marion G. Peters,  Adrian M. Di Bisceglie,  Kent G. Benner,  Kris V. Kowdley,  Robert L. Carithers Jr.,  Leonard Rosoff Jr.,  Guadalupe Garcia-Tsao,  James L. Boyer,  Thomas D. Boyer,  Enrique J. Martinez,  Nathan M. Bass,  John R. Lake,  David S. Barnes,  Maurizio Bonacini,  Karen L. Lindsay,  A. Scott Mills,  Rodney S. Markin,  Raphael Rubin,  A. Brian West,  Donald E. Wheeler,  Melissa J. Contos,  Alan F. Hofmann, 
  • Pages: 1184-1193
  • First Published: 25 October 2005
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Risk factors and comorbidities in primary biliary cirrhosis: A controlled interview-based study of 1032 patients†

M. Eric Gershwin,  Carlo Selmi,  Howard J. Worman,  Ellen B. Gold,  Mitchell Watnik,  Jessica Utts,  Keith D. Lindor,  Marshall M. Kaplan,  John M. Vierling,  USA PBC Epidemiology Group , 
  • Pages: 1194-1202
  • First Published: 25 October 2005

Hepatology Elsewhere

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What happens to cirrhotic cardiomyopathy after liver transplantation?†

Hongqun Liu,  Samuel S. Lee, 
  • Pages: 1203-1205
  • First Published: 25 October 2005
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Placebo controlled treatment trials in hepatic encephalopathy are feasible and ethical†

Ravi K. Ghanta M.D.,  Kevin D. Mullen M.D., 
  • Pages: 1206-1207
  • First Published: 25 October 2005

AASLD Practice Guideline

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Management of hepatocellular carcinoma†

Jordi Bruix,  Morris Sherman, 
  • Pages: 1208-1236
  • First Published: 25 October 2005

Correspondence

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In type 1 autoimmune hepatitis, is cirrhosis at presentation or follow-up associated with a poorer outcome?†

Sumita Verma,  Allan Redeker, 
  • Page: 1237
  • First Published: 25 October 2005
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Reply†

Jordan Feld,  E. Jenny Heathcote, 
  • Pages: 1237-1238
  • First Published: 25 October 2005