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ISSUE INFORMATION
EDITORIALS
GLUCOLD, eosinophils and chronic obstructive pulmonary disease
- Pages: 966-967
- First Published: 26 June 2018
Managing disease behaviour: A team approach
- Pages: 968-969
- First Published: 20 August 2018
Does virtual bronchoscopic navigation improve the diagnostic yield of transbronchial biopsy?
- Pages: 970-971
- First Published: 26 August 2018
Does CPAP for obstructive sleep apnoea improve asthma control?
- Pages: 972-973
- First Published: 20 August 2018
Repurposing metformin to prevent and treat tuberculosis
- Pages: 974-975
- First Published: 19 July 2018
COMMENTARY
Melbourne epidemic thunderstorm asthma event 2016: Lessons learnt from the perfect storm
- Pages: 976-977
- First Published: 19 September 2018
INVITED REVIEW SERIES
Tuberculosis Updates 2018
New drugs and regimens for tuberculosis
- Pages: 978-990
- First Published: 19 June 2018
Molecular Techniques for Respiratory Diseases
How do new molecular tools apply to my clinical practice?
- Pages: 991-992
- First Published: 14 August 2018
Proteomics: Clinical and research applications in respiratory diseases
- Pages: 993-1003
- First Published: 13 August 2018
Paediatric and Adult Bronchiectasis
Moving forward: Bronchiectasis and chronic suppurative lung disease in children and adults in the 21st century
- Pages: 1004-1005
- First Published: 25 March 2018
Bronchiectasis: Treatment decisions for pulmonary exacerbations and their prevention
- Pages: 1006-1022
- First Published: 11 September 2018
ORIGINAL ARTICLES
COPD
Predictive value of eosinophils and neutrophils on clinical effects of ICS in COPD
- Pages: 1023-1031
- First Published: 26 April 2018

Blood eosinophils, in contrast to neutrophils, reflect eosinophils in sputum, biopsies and bronchoalveolar lavage (BAL), in inhaled corticosteroids (ICS)-naïve COPD patients. However, both baseline eosinophils and neutrophils, whether measured in blood, sputum, biopsies and BAL, insufficiently predict lung function response to ICS in COPD over a period of 6–30 months.
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Interstitial Lung Disease
Prognostic factors and disease behaviour of pathologically proven fibrotic non-specific interstitial pneumonia
- Pages: 1032-1040
- First Published: 24 April 2018
Non-specific interstitial pneumonia (NSIP) has heterogeneous characteristics in terms of background, disease behaviour and prognosis. Some patients with idiopathic fibrotic NSIP with or without interstitial pneumonia with autoimmune features (IPAF) showed progressive disease despite therapy.
Multidimensional improvement in connective tissue disease-associated interstitial lung disease: Two courses of pulse dose methylprednisolone followed by low-dose prednisone and tacrolimus
- Pages: 1041-1048
- First Published: 16 July 2018

Two courses of pulse dose methylprednisolone therapy followed by 1 year of tacrolimus combination therapy with corticosteroids was well tolerated and improved not only lung physiology but also exercise capacity, exercise oxygen desaturation and patient-reported outcomes (PRO) such as dyspnoea and health-related quality of life (HRQoL).
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Lung cancer
Virtual bronchoscopic navigation as an aid to CT-guided transbronchial biopsy improves the diagnostic yield for small peripheral pulmonary lesions
- Pages: 1049-1054
- First Published: 07 August 2018
Computed tomography (CT)-guided transbronchial biopsy (CT-TBB) is one of the several procedures used to diagnose small peripheral pulmonary lesions (PPL), although its diagnostic yield is unsatisfying. We now report that a combined approach in which virtual bronchoscopic navigation (VBN) is used to assist CT-TBB improves the diagnostic yield for small PPL.
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Sleep and Ventilation
Continuous positive airway pressure for obstructive sleep apnoea does not improve asthma control
- Pages: 1055-1062
- First Published: 10 July 2018
In this randomized controlled trial involving patients with nocturnal asthma and snoring despite taking moderate-to-high-dose inhaled corticosteroid and long-acting bronchodilators, continuous positive airway pressure (CPAP) therapy for 3 months did not improve asthma control but led to better asthma-related quality of life and vitality than those on conservative treatment.
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Tuberculosis
Metformin is associated with a lower risk of active tuberculosis in patients with type 2 diabetes
- Pages: 1063-1073
- First Published: 25 June 2018
This retrospective, propensity score-matched cohort study demonstrated that the risk of active tuberculosis (TB) is higher in the type 2 diabetes mellitus population. However, the use of metformin is associated with a decreased risk of active TB in this population.
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LETTER FROM ASIA-PACIFIC REGION
CORRESPONDENCES
Red blood cell transfusion in acute pulmonary embolism
- Page: 1076
- First Published: 19 September 2018
See Reply
Red blood cell transfusion in acute pulmonary embolism – Reply
- Pages: 1076-1077
- First Published: 19 September 2018
See Letter