• Issue

    Clinical & Experimental Immunology: Volume 181, Issue 3

    385-527
    September 2015
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Review Article

Open Access

Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: recommendations of the Innovative Medicines Initiative ABIRISK consortium

B. Rup,  M. Pallardy,  D. Sikkema,  T. Albert,  M. Allez,  P. Broet,  C. Carini,  P. Creeke,  J. Davidson,  N. De Vries,  D. Finco,  A. Fogdell-Hahn,  E. Havrdova,  A. Hincelin-Mery,  M. C. Holland,  P. E. H. Jensen,  E. C. Jury,  H. Kirby,  D. Kramer,  S. Lacroix-Desmazes,  J. Legrand,  E. Maggi,  B. Maillère,  X. Mariette,  C. Mauri,  V. Mikol,  D. Mulleman,  J. Oldenburg,  G. Paintaud,  C. R. Pedersen,  N. Ruperto,  R. Seitz,  S. Spindeldreher,  F. Deisenhammer,  on behalf of the ABIRISK Consortium , 
  • Pages: 385-400
  • First Published: 08 May 2015

Translational

Autoimmunity

Anti-tumour necrosis factor treatment increases circulating T helper type 17 cells similarly in different types of inflammatory arthritis

D. N. Hull,  R. O. Williams,  E. Pathan,  S. Alzabin,  S. Abraham,  P. C. Taylor, 
  • Pages: 401-406
  • First Published: 11 March 2015
Open Access

Targeted IgA Fc receptor I (FcαRI) therapy in the early intervention and treatment of pristane-induced lupus nephritis in mice

C. Liu,  Y. Kanamaru,  T. Watanabe,  N. Tada,  S. Horikoshi,  Y. Suzuki,  Z. Liu,  Y. Tomino, 
  • Pages: 407-416
  • First Published: 23 April 2015

Decreased levels of autoantibodies against apolipoprotein B-100 antigens are associated with cardiovascular disease in systemic lupus erythematosus

Elisabet Svenungsson,  Daniel Engelbertsen,  Maria Wigren,  Johanna T Gustafsson,  Iva Gunnarsson,  Kerstin Elvin,  Kerstin Jensen-Urstad,  Gunilla Nordin Fredrikson,  Jan Nilsson, 
  • Pages: 417-426
  • First Published: 08 May 2015

The exaggerated inflammatory response in Behçet's syndrome: identification of dysfunctional post-transcriptional regulation of the IFN-γ/CXCL10 IP-10 pathway

N. Ambrose,  E. Khan,  R. Ravindran,  L. Lightstone,  S. Abraham,  M. Botto,  M. Johns,  D. O. Haskard, 
  • Pages: 427-433
  • First Published: 18 May 2015

Immune deficiency

Defective trained immunity in patients with STAT-1-dependent chronic mucocutaneaous candidiasis

D. C. Ifrim,  J. Quintin,  L. Meerstein-Kessel,  T. S. Plantinga,  L. A. B. Joosten,  J. W. M. van der Meer,  F. L. van de Veerdonk,  M. G. Netea, 
  • Pages: 434-440
  • First Published: 16 April 2015
Open Access

Efficacy and tolerability of 16% subcutaneous immunoglobulin compared with 20% subcutaneous immunoglobulin in primary antibody deficiency

H. B. Niebur,  C. M. Duff,  G. F. Shear,  D. Nguyen,  T. K. Alberdi,  M. J. Dorsey,  J. W. Sleasman, 
  • Pages: 441-450
  • First Published: 11 March 2015

Infection

T cell anergy and activation are associated with suboptimal humoral responses to measles revaccination in HIV-infected children on anti-retroviral therapy in Nairobi, Kenya

M. B. Buechler,  L. P. Newman,  B. H. Chohan,  A. Njoroge,  D. Wamalwa,  C. Farquhar, 
  • Pages: 451-456
  • First Published: 04 March 2015

The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load

Kjetil H. Egge,  Andreas Barratt-Due,  Stig Nymo,  Julie K. Lindstad,  Anne Pharo,  Corinna Lau,  Terje Espevik,  Ebbe B. Thorgersen,  Tom E. Mollnes, 
  • Pages: 457-467
  • First Published: 23 April 2015

Insight into the beneficial immunomodulatory mechanism of the sevoflurane metabolite hexafluoro-2-propanol in a rat model of endotoxaemia

M. Urner,  M. Schläpfer,  I. K. Herrmann,  M. Hasler,  R. R. Schimmer,  C. Booy,  B. Roth Z'graggen,  H. Rehrauer,  F. Aigner,  R. D. Minshall,  W. J. Stark,  B. Beck-Schimmer, 
  • Pages: 468-479
  • First Published: 29 April 2015

Inflammation

Interleukin-1 family cytokines and their regulatory proteins in normal pregnancy and pre-eclampsia

J. H. Southcombe,  C. W. G. Redman,  I. L. Sargent,  I. Granne, 
  • Pages: 480-490
  • First Published: 18 February 2015

Impact of irradiation and immunosuppressive agents on immune system homeostasis in rhesus macaques

C. Meyer,  J. Walker,  J. Dewane,  F. Engelmann,  W. Laub,  S. Pillai,  Charles. R. Thomas Jr,  I. Messaoudi, 
  • Pages: 491-510
  • First Published: 22 April 2015

Real-time quantitative reverse transcription–polymerase chain reaction to detect propionibacterial ribosomal RNA in the lymph nodes of Chinese patients with sarcoidosis

Y. Zhou,  Y.-R. Wei,  Y. Zhang,  S.-S. Du,  R. P. Baughman,  H.-P. Li, 
  • Pages: 511-517
  • First Published: 10 May 2015

Neutrophil extracellular traps can activate alternative complement pathways

H. Wang,  C. Wang,  M.-H. Zhao,  M. Chen, 
  • Pages: 518-527
  • First Published: 11 May 2015