• Issue

    Cancer Science: Volume 101, Issue 5

    i, 1073-1330
    May 2010
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In this Issue

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In this Issue

  • Page: i
  • First Published: 19 April 2010

REVIEW ARTICLE

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Insulin resistance and cancer: Epidemiological evidence

Shoichiro Tsugane,  Manami Inoue, 
  • Pages: 1073-1079
  • First Published: 19 April 2010

ORIGINAL ARTICLES

BASIC AND CLINICAL IMMUNOLOGY

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Fc-engineered EGF-R antibodies mediate improved antibody-dependent cellular cytotoxicity (ADCC) against KRAS-mutated tumor cells

Martin Schlaeth,  Sven Berger,  Stefanie Derer,  Katja Klausz,  Stefan Lohse,  Michael Dechant,  Greg A. Lazar,  Tanja Schneider-Merck,  Matthias Peipp,  Thomas Valerius, 
  • Pages: 1080-1088
  • First Published: 19 April 2010
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Sensitive immunohistochemical detection of WT1 protein in tumors with anti-WT1 antibody against WT1 235 peptide

Ryo Ichinohasama,  Yusuke Oji,  Hisayuki Yokoyama,  Kengo Takeuchi,  Tohru Fujiwara,  Kenichi Ishizawa,  Osamu Taniguchi,  Akihiro Tsuboi,  Yoshihiro Oka,  Haruo Sugiyama, 
  • Pages: 1089-1092
  • First Published: 19 April 2010

CARCINOGENESIS

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Glutathione S-transferase A4 is a positive marker for rat hepatic foci induced by clofibrate and genotoxic carcinogens

Takeshi Shimizu,  Yang Fan,  Daisuke Yamana,  Takuya Miura,  Naoki Nanashima,  Toshiyuki Yamada,  Shigeki Tsuchida, 
  • Pages: 1093-1098
  • First Published: 19 April 2010
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Dynamic alteration of protein expression profiles during neoplastic transformation of rat hepatic oval-like cells

Xuefei Li,  Yan Li,  Xiaonan Kang,  Kun Guo,  Haiyu Li,  Dongmei Gao,  Lu Sun,  Yinkun Liu, 
  • Pages: 1099-1107
  • First Published: 19 April 2010

CELL, MOLECULAR, AND STEM CELL BIOLOGY

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TGF-β1 signal pathway may contribute to rhabdomyosarcoma development by inhibiting differentiation

Shouli Wang,  Lingchuan Guo,  Liang Dong,  Lingling Guo,  Shigang Li,  Jiajia Zhang,  Maomin Sun, 
  • Pages: 1108-1116
  • First Published: 19 April 2010
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Lentiviral shRNA silencing of BDNF inhibits in vivo multiple myeloma growth and angiogenesis via down-regulated stroma-derived VEGF expression in the bone marrow milieu

Lu Zhang,  Yu Hu,  Chun-yan Sun,  Jiang Li,  Tao Guo,  Jing Huang,  Zhang-bo Chu, 
  • Pages: 1117-1124
  • First Published: 19 April 2010
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Mitochondria regulate the unfolded protein response leading to cancer cell survival under glucose deprivation conditions

Naomi Haga,  Sakae Saito,  Yoshinori Tsukumo,  Junko Sakurai,  Aki Furuno,  Takashi Tsuruo,  Akihiro Tomida, 
  • Pages: 1125-1132
  • First Published: 19 April 2010
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Epidermal growth factor-dependent enhancement of invasiveness of squamous cell carcinoma of the breast

Fuyo Kimura,  Keiichi Iwaya,  Tokuichi Kawaguchi,  Hiroshi Kaise,  Kimito Yamada,  Kiyoshi Mukai,  Osamu Matsubara,  Norihiko Ikeda,  Norio Kohno, 
  • Pages: 1133-1140
  • First Published: 19 April 2010
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Subcellular distribution of S100A4 and its transcriptional regulation under hypoxic conditions in gastric cancer cell line BGC823

Ruixiu Zhang,  Hao Fu,  Danqi Chen,  Jun Hua,  Yanping Hu,  Kailai Sun,  Xiuju Sun, 
  • Pages: 1141-1146
  • First Published: 19 April 2010
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Analysis of DOK-6 function in downstream signaling of RET in human neuroblastoma cells

Ai Kurotsuchi,  Yoshiki Murakumo,  Mayumi Jijiwa,  Kei Kurokawa,  Yasutomo Itoh,  Yoshinori Kodama,  Takuya Kato,  Atsushi Enomoto,  Naoya Asai,  Hiroko Terasaki,  Masahide Takahashi, 
  • Pages: 1147-1155
  • First Published: 19 April 2010
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Inhibition of ErbB2 by Herceptin reduces survivin expression via the ErbB2–β-catenin/TCF4-survivin pathway in ErbB2-overexpressed breast cancer cells

Hongxia Zhu,  Guo Zhang,  Yan Wang,  Ninghong Xu,  Shun He,  Wei Zhang,  Meigui Chen,  Mei Liu,  Lanping Quan,  Jingfeng Bai,  Ningzhi Xu, 
  • Pages: 1156-1162
  • First Published: 19 April 2010
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Novel combination treatment for colorectal cancer using Nek2 siRNA and cisplatin

Kazushi Suzuki,  Toshio Kokuryo,  Takeshi Senga,  Yukihiro Yokoyama,  Masato Nagino,  Michinari Hamaguchi, 
  • Pages: 1163-1169
  • First Published: 19 April 2010
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Pigpen, a nuclear coiled body component protein, is involved in angiogenesis

Tomoko Yoshida,  Yasufumi Sato,  Ikuo Morita,  Mayumi Abe, 
  • Pages: 1170-1176
  • First Published: 19 April 2010
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Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatin

Masaki Shiota,  Akira Yokomizo,  Eiji Kashiwagi,  Yasuhiro Tada,  Junichi Inokuchi,  Katsunori Tatsugami,  Kentaro Kuroiwa,  Takeshi Uchiumi,  Narihito Seki,  Seiji Naito, 
  • Pages: 1177-1185
  • First Published: 19 April 2010
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Hyperthermia-associated carboplatin resistance: Differential role of p53, HSF1 and Hsp70 in hepatoma cells

Aanchal Sharma,  Avtar Singh Meena,  Manoj Kumar Bhat, 
  • Pages: 1186-1193
  • First Published: 19 April 2010

CLINICAL RESEARCH

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Clinical study of asbestos-related lung cancer in Japan with special reference to occupational history

Takumi Kishimoto,  Kenichi Gemba,  Nobukazu Fujimoto,  Kazuo Onishi,  Ikuji Usami,  Keiichi Mizuhashi,  Kiyonobu Kimura, 
  • Pages: 1194-1198
  • First Published: 19 April 2010
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First-line therapy with doxycycline in ocular adnexal mucosa-associated lymphoid tissue lymphoma: A retrospective analysis of clinical predictors

Tae Min Kim,  Ki Hwan Kim,  Min Joung Lee,  Yoon Kyung Jeon,  Se-Hoon Lee,  Dong-Wan Kim,  Chul Woo Kim,  Il Han Kim,  Sang In Khwarg,  Dae Seog Heo, 
  • Pages: 1199-1203
  • First Published: 19 April 2010

DRUG DISCOVERY AND DELIVERY

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Aurora A selective inhibitor MLN8237 suppresses the growth and survival of HTLV-1-infected T-cells in vitro

Mariko Tomita,  Naoki Mori, 
  • Pages: 1204-1211
  • First Published: 19 April 2010
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Mechanism of antitumor effect of a novel bFGF binding peptide on human colon cancer cells

Cong Wang,  Shaoqiang Lin,  Yanfang Nie,  Xinglong Jia,  Jing Wang,  Jian Xiao,  Jianzhang Wu,  Xiaokun Li,  Xiaoping Wu, 
  • Pages: 1212-1218
  • First Published: 19 April 2010
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Combination of vesicular stomatitis virus matrix protein gene therapy with low-dose cisplatin improves therapeutic efficacy against murine melonoma

Shan Luo,  Ping Chen,  Zi-chao Luo,  Ping Zhang,  Ping Sun,  Wei Shi,  Zhi-yong Li,  Xiao-long Zhang,  Li-qiang Wang,  Xin Chen,  Yu-quan Wei,  Yan-jun Wen, 
  • Pages: 1219-1225
  • First Published: 19 April 2010
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Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis

Wei Li,  Li Xie,  Zheng Chen,  Yi Zhu,  Yujie Sun,  Yi Miao,  Zekuan Xu,  Xiao Han, 
  • Pages: 1226-1233
  • First Published: 19 April 2010

EPIDEMIOLOGY AND PREVENTION

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Association between vitamin D and calcium intake and breast cancer risk according to menopausal status and receptor status in Japan

Takakazu Kawase,  Keitaro Matsuo,  Takeshi Suzuki,  Kaoru Hirose,  Satoyo Hosono,  Miki Watanabe,  Masaki Inagaki,  Hiroji Iwata,  Hideo Tanaka,  Kazuo Tajima, 
  • Pages: 1234-1240
  • First Published: 19 April 2010
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Secular trends in breast cancer mortality in five East Asian populations: Hong Kong, Japan, Korea, Singapore and Taiwan

Hai-Rim Shin,  Mathieu Boniol,  Clementine Joubert,  Clarisse Hery,  Jari Haukka,  Philippe Autier,  Yoshikazu Nishino,  Tomotaka Sobue,  Chien-Jen Chen,  San-Lin You,  Sei Hyun Ahn,  Kyu Won Jung,  Stephen Chun-Key Law,  Oscar Mang,  Kee-Seng Chia, 
  • Pages: 1241-1246
  • First Published: 19 April 2010

GENETICS, GENOMICS AND PROTEOMICS

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BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin

Hyun Jeong Shim,  Joo Young Yun,  Jun Eul Hwang,  Woo Kyun Bae,  Sang Hee Cho,  Ji Hee Lee,  Hee Nam Kim,  Min Ho Shin,  Sun Seog Kweon,  Jae Hyuk Lee,  Hyeoung Joon Kim,  Ik Joo Chung, 
  • Pages: 1247-1254
  • First Published: 19 April 2010
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Frequent hypermethylation and loss of heterozygosity of the testis derived transcript gene in ovarian cancer

Haifeng Qiu,  Jiezhi Zhu,  Cunzhong Yuan,  Shi Yan,  Qifeng Yang,  Beihua Kong, 
  • Pages: 1255-1260
  • First Published: 19 April 2010
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Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer

Motohisa Tada,  Fumihiko Kanai,  Yasuo Tanaka,  Masashi Sanada,  Yasuhito Nannya,  Keisuke Tateishi,  Miki Ohta,  Yoshinari Asaoka,  Motoko Seto,  Fumio Imazeki,  Haruhiko Yoshida,  Seishi Ogawa,  Osamu Yokosuka,  Masao Omata, 
  • Pages: 1261-1269
  • First Published: 19 April 2010

PATHOLOGY

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Pleomorphic phenotypes of gastrointestinal stromal tumors at metastatic sites with or without imatinib treatment

Kazuha Sakamoto,  Shinji Sakurai,  Tatsuo Kanda,  Yuji Sakuma,  Tsunekazu Hishima,  Mitsugu Hironaka,  Takeo Bamba,  Yoshiko Keira,  Yasuo Takano,  Toshiro Niki,  Tadashi Hasegawa,  Seiichi Hirota, 
  • Pages: 1270-1278
  • First Published: 19 April 2010
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Overexpression of yes-associated protein contributes to progression and poor prognosis of non-small-cell lung cancer

Yang Wang,  Qianze Dong,  Qingfu Zhang,  Zixuan Li,  Enhua Wang,  Xueshan Qiu, 
  • Pages: 1279-1285
  • First Published: 19 April 2010
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Adipocytokines as new promising markers of colorectal tumors: Adiponectin for colorectal adenoma, and resistin and visfatin for colorectal cancer

Takako Eguchi Nakajima,  Yasuhide Yamada,  Tetsutaro Hamano,  Koh Furuta,  Takahisa Matsuda,  Shin Fujita,  Ken Kato,  Tetsuya Hamaguchi,  Yasuhiro Shimada, 
  • Pages: 1286-1291
  • First Published: 19 April 2010
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Expression of NDRG2 in esophageal squamous cell carcinoma

Hai Shi,  Nanlin Li,  Shujun Li,  Changsheng Chen,  Weizhong Wang,  Chunsheng Xu,  Jian Zhang,  Haifeng Jin,  Hongwei Zhang,  Huadong Zhao,  Wenjie Song,  Quanxin Feng,  Xiangying Feng,  Xin Shen,  Libo Yao,  Qingchuan Zhao, 
  • Pages: 1292-1299
  • First Published: 19 April 2010
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Matrix metalloproteinase-7 as a marker of metastasis and predictor of poor survival in bladder cancer

Tibor Szarvas,  Markus Becker,  Frank Vom Dorp,  Carolin Gethmann,  Martin Tötsch,  Ágnes Bánkfalvi,  Kurt W. Schmid,  Imre Romics,  Herbert Rübben,  Süleyman Ergün, 
  • Pages: 1300-1308
  • First Published: 19 April 2010
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Clinicopathologic correlations of diffuse large B-cell lymphoma in rheumatoid arthritis patients treated with methotrexate

Nozomi Niitsu,  Masataka Okamoto,  Hirokazu Nakamine,  Masami Hirano, 
  • Pages: 1309-1313
  • First Published: 19 April 2010
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Expression and prognostic significance of osteopontin and caspase-3 in hepatocellular carcinoma patients after curative resection

Hua Huang,  Xiao-Fei Zhang,  Hai-Jun Zhou,  Yu-Hua Xue,  Qiong-Zhu Dong,  Qing-Hai Ye,  Lun-Xiu Qin, 
  • Pages: 1314-1319
  • First Published: 19 April 2010
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DJ-1: A novel independent prognostic marker for survival in glottic squamous cell carcinoma

Xiao-Lin Zhu,  Zhang-Feng Wang,  Wen-Bin Lei,  Hui-Wen Zhuang,  Hong-Yan Jiang,  Wei-Ping Wen, 
  • Pages: 1320-1325
  • First Published: 19 April 2010
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Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma

Reiko Nakai,  Yoshimasa Maniwa,  Yugo Tanaka,  Wataru Nishio,  Masahiro Yoshimura,  Yutaka Okita,  Chiho Ohbayashi,  Naoyuki Satoh,  Hisakazu Ogita,  Yoshimi Takai,  Yoshitake Hayashi, 
  • Pages: 1326-1330
  • First Published: 19 April 2010