Resurgence in the Practical Use of Physiologically‐Based Pharmacokinetics (PBPK) Allied with In Vitro In Vivo Extrapolations (IVIVE) in Drug Development: Biopharmaceutics & Drug Disposition: Vol 33, No 2

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Biopharmaceutics & Drug Disposition: Volume 33, Issue 2

Special Issue:Resurgence in the Practical Use of Physiologically‐Based Pharmacokinetics (PBPK) Allied with In Vitro In Vivo Extrapolations (IVIVE) in Drug Development

Editorial Commentaries

Physiologically based pharmacokinetic (PBPK) modeling: It is here to stay!

Invited Commentaries

PBPK as a tool in regulatory review

An industrial perspective on contemporary applications of PBPK models in drug discovery and development

Reviews

Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?

Using Simcyp to project human oral pharmacokinetic variability in early drug research to mitigate mechanism-based adverse events

Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies

Utility of a physiologically–based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug–drug–disease interaction scenario for rivaroxaban during the drug review process: implications for clinical practice

From preclinical to human – prediction of oral absorption and drug–drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in an industrial setting: a workflow by using case example

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Biopharmaceutics & Drug Disposition: Volume 33, Issue 2

Special Issue:Resurgence in the Practical Use of Physiologically‐Based Pharmacokinetics (PBPK) Allied with In Vitro In Vivo Extrapolations (IVIVE) in Drug Development

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Editorial Commentaries

Physiologically based pharmacokinetic (PBPK) modeling: It is here to stay!

Invited Commentaries

PBPK as a tool in regulatory review

An industrial perspective on contemporary applications of PBPK models in drug discovery and development

Reviews

Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?

Using Simcyp to project human oral pharmacokinetic variability in early drug research to mitigate mechanism-based adverse events

Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies

Utility of a physiologically–based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug–drug–disease interaction scenario for rivaroxaban during the drug review process: implications for clinical practice

From preclinical to human – prediction of oral absorption and drug–drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in an industrial setting: a workflow by using case example

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