Previous Issue|Next Issue
Export Citation(s)Download PDF(s)

Prefaces

Preface

Byron Jones, 
  • Page: 2535
  • First Published: 14 August 2001

Research Articles

Theory and practice in medical statistics

Peter Armitage, 
  • Pages: 2537-2548
  • First Published: 14 August 2001

The impact of the international guideline entitled Statistical Principles for Clinical Trials (ICH E9)

J. Lewis,  W. Louv,  F. Rockhold,  T. Sato, 
  • Pages: 2549-2560
  • First Published: 14 August 2001

Statistical considerations of FDA and CPMP rules for the investigation of new anti-bacterial products

Joachim Röhmel, 
  • Pages: 2561-2571
  • First Published: 14 August 2001

Independent data monitoring committees: rationale, operations and controversies†

Susan S. Ellenberg, 
  • Pages: 2573-2583
  • First Published: 14 August 2001

Non-parametric analysis of covariance for confirmatory randomized clinical trials to evaluate dose–response relationships

Catherine M. Tangen,  Gary G. Koch, 
  • Pages: 2585-2607
  • First Published: 14 August 2001

Applying sample survey methods to clinical trials data

L. M. LaVange,  G. G. Koch,  T. A. Schwartz, 
  • Pages: 2609-2623
  • First Published: 14 August 2001

Sample size re-estimation: recent developments and practical considerations

A. Lawrence Gould, 
  • Pages: 2625-2643
  • First Published: 14 August 2001

Sample size recalculation using conditional power

Jonathan S. Denne, 
  • Pages: 2645-2660
  • First Published: 14 August 2001

The continual reassessment method and its applications: a Bayesian methodology for phase I cancer clinical trials

Naoki Ishizuka,  Yasuo Ohashi, 
  • Pages: 2661-2681
  • First Published: 14 August 2001

Paradigm shifts in clinical trials enabled by information technology

Ronald G. Marks,  Michael Conlon,  Stephen J. Ruberg, 
  • Pages: 2683-2696
  • First Published: 14 August 2001

Enhancing the value delivered by the statistician throughout drug discovery and development: putting statistical science into regulated pharmaceutical innovation

Gregory G. Enas,  John S. Andersen, 
  • Pages: 2697-2708
  • First Published: 14 August 2001

Exact inference for categorical data: recent advances and continuing controversies

Alan Agresti, 
  • Pages: 2709-2722
  • First Published: 14 August 2001

Computational tools for exact conditional logistic regression

Chris Corcoran,  Cyrus Mehta,  Nitin Patel,  Pralay Senchaudhuri, 
  • Pages: 2723-2739
  • First Published: 14 August 2001

A multiple imputation strategy for incomplete longitudinal data

Mary Beth Landrum,  Mark P. Becker, 
  • Pages: 2741-2760
  • First Published: 14 August 2001

A method for the analysis of repeated binary outcomes in randomized clinical trials with non-compliance

Tosiya Sato, 
  • Pages: 2761-2774
  • First Published: 14 August 2001

Some statistical issues in modelling pharmacokinetic data

J. K. Lindsey,  B. Jones,  P. Jarvis, 
  • Pages: 2775-2783
  • First Published: 14 August 2001

Statistical issues in bioequivalance

Stephen Senn, 
  • Pages: 2785-2799
  • First Published: 14 August 2001