Journal of Neurochemistry

Overview

The Journal of Neurochemistry is dedicated to disseminating research covering all aspects of neurochemistry. The journal scope includes studies on genetic, molecular, cellular and biochemical aspects of the nervous system, the pathogenesis of neurological and psychiatric disorders, and the development of specific biomarkers for nervous system diseases and conditions. We prioritize original research that mechanistically demonstrates an advance as well as critical reviews that highlight progression of knowledge in the field. The Journal of Neurochemistry is devoted to the prompt publication of original findings of the highest scientific priority and value that provide novel mechanistic insights, represent a clear advance over previous studies and have the potential to generate exciting future research.

The Journal of Neurochemistry does not publish work relating to biological extracts of unknown chemical composition or purity. All compounds reported must have a known chemical structure and concentration.

The Journal of Neurochemistry publishes full-length presentations of significant original findings, and also narrative and systematic reviews, submitted by investigators with relevant expertise. Articles are published in the following categories. Please note that these definitions are not exhaustive, and your research may fall into more than one category.

Gene regulation & Genomics covers the regulation of gene expression, specifically its control by regulatory non-coding and coding RNA species that may initiate, block, or modulate the expression levels of detected transcripts by interacting with them and changing their levels and/or properties.

Brain Development & Cell Differentiation covers investigations into the molecular mechanisms of nervous system development and regeneration. It includes the regulation of neural development and regeneration by the extracellular environment and intrinsic programs, and the impact of genetic and environmental factors on brain development.

Synaptic Plasticity covers manuscripts on structural and functional aspects of synaptic plasticity, including homeostatic and pathophysiological forms, and the role of glial cells and extracellular matrix in synaptic transmission dynamics underlying neural information processing. It includes in vitro and in vivo research, biochemical, molecular, and cellular mechanisms involved in synapse formation, maintenance, resilience, and in synaptopathies.

Bioenergetics & Metabolism covers the molecular mechanisms that conserve and transform energy into biological processes in the central nervous system. It includes any aspect that links metabolism with signaling at the cellular and intercellular interaction levels, involving the mitochondrial, lysosomal, or cytosolic biochemical transformations that sustain neurotransmission and higher-order functions.

Neuroinflammation & Neuroimmunology covers research exploring the functional interactions between immune system cells and the central nervous system, in contexts such as health, disease, aging, or injury. This area intersects and is relevant to many fields including immunity, neuroscience, biochemistry, endocrinology, genomics, and pathology.

Neuronal Plasticity and Behavior covers research investigating how gene products, neurotransmitters, and psychotropic drugs regulate synaptic properties and circuits that modulate learning, memory and affective/cognitive behaviors. It includes research on preclinical models aimed at understanding mechanistically how gene variants associated with neurological and neuropsychiatric disorders model human traits altered in these diseases.

Molecular Basis of Disease covers research relating to molecular mechanisms that underpin neurological and psychiatric illnesses. It includes studies using model systems that provide new approaches and the identification and/or validation of novel therapeutic targets, as well as their targeting with potential treatment modalities (such as small molecules, biologics, RNA and related strategies).

Clinical studies, Biomarkers & Imaging covers research dedicated to fluid and imaging biomarkers in early diagnosis, biomarker-driven clinical trials, and precision medicine. It includes read-out changes indicating altered signaling pathway networks, regulation of post-translational modifications, or proteolytic processing, that are supportive to define key pathological molecular mechanisms. Studies including neurochemical data from clinical studies and patient follow-up are also welcome, as well as guidelines for pre-analytical and analytical factors related with biomarker development, biospecimen collection technologies, and diagnostics refinement.

Neurotools, Methods & Neurochemistry Resources welcomes manuscripts detailing novel methods, techniques, reagents and analytical pipelines or strategies for neurochemistry research. This includes development of genetically manipulated organisms and viral vectors, along with biologicals and other reagents. This category reflects the dynamic nature of technology development in contemporary research.

The Journal of Neurochemistry encourages the use of ORCID, a non-profit, community-based effort to uniquely identify authors and link articles and other research activities to specific individuals. Authors have the opportunity to add their ORCID identifier to their user profiles on https://wiley.atyponrex.com/journal/JNC or upon submission of an article. Once you provide your ORCID identifier, it will be tied to your profile and automatically available for future submissions. Further information can be found on http://orcid.org/

Why publish in Journal of Neurochemistry?

Simplified and Easy Submission Process

We make it easy for you to submit papers through our streamlined online process. Once your paper is submitted, you can keep track of its progress through our detailed production tracking service on Author Services. Our Author Centre helps you access the editing and translation service and promotional tools to help you maximize the outreach of your article. We also provide access to relevant information about your published article including article level metrics.

Quality Peer Review

Qualified reviewers and constructive comments are the keys to a great review. At the Journal of Neurochemistry, our reviewers are among the top researchers in their fields, and we pride ourselves on providing detailed and workable comments and critiques. We cut down on revision times by giving precise feedback at the start, so that you and your colleagues know exactly how to edit your work for publication. Our goal is to work with you to make each paper a valuable contribution to the field.

Fast Decision and Publication Times

Faster decision and publication times mean that your research has an impact quickly —it is read and cited sooner! The Journal of Neurochemistry achieves an average 27 days to first decision.

Expanded Access for Your Article

The Journal of Neurochemistry offers an Open Access option and is compliant with public access policies from NIH, RCUK and other funders. We offer APC discounts for members of the International Society for Neurochemistry. All review articles are free from online publication. The Journal of Neurochemistry supports access to researchers in developing countries through the Research 4 Life initiative. All articles are in enhanced HTML format, which includes figure and reference viewers, and links to supporting information. PDF versions include reference links to supporting information in an online-friendly format. PDFs are enhanced with ReadCube, which makes all text searchable and annotatable and provides simple click-through to author and reference information.

For author guidelines, click here.

Full archive online
Every issue of the Journal of Neurochemistry is available online from volume 1, issue 1 (May 1956). This archive is available free to all International Society for Neurochemistry (ISN) members. Institutions can purchase these backfiles (1956-1996 issues) for a one-off fee for archival rights and access in perpetuity: click here for details. All content from 1997 volumes onwards is made freely available to all users 12 months from publication.

NIH-funded authors and Journal of Neurochemistry
The NIH is mandating grantees to deposit their peer-reviewed author manuscripts in PubMed Central, to be made publicly available within 12 months of publication. The NIH mandate applies to all articles based on research that has been wholly or partially funded by the NIH and that are accepted for publication on or after April 7, 2008.

In order to help authors comply with the NIH mandate, for papers accepted for publication in the Journal of Neurochemistry after this date, Wiley-Blackwell will post the accepted manuscript (incorporating all amendments made during peer review, but prior to the publisher’s copy-editing and typesetting) of articles by NIH grant-holders to PubMed Central at the point of acceptance by the journal. This version will then be made publicly available in PubMed Central 12 months after publication. Following the deposit, Wiley-Blackwell authors will receive further communications from the NIH with respect to the submission. For further information, see here.

If authors wish to make their final published article openly accessible and without a 12-month embargo, they can choose to publish via the Open Access service.

Wellcome and HHMI grantees can find out further information here.

Keywords

Journal of Neurochemistry, neurochemistry, biochemistry, neuroscience, molecular biology, cell biology, nervous system, pharmacology, histochemistry, immunology