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ARTICLE
Open Access

oa

The oral ferroportin inhibitor vamifeport prevents liver iron overload in a mouse model of hemochromatosis
Naja Nyffenegger, Anna Flace, Ahmet Varol, Patrick Altermatt, Cédric Doucerain, Hanna Sundstrom, Franz Dürrenberger, Vania Manolova,

First published: 12 September 2024

Graphical Abstract
ARTICLE
Open Access

oa

A cellular reporter system to evaluate endogenous fetal hemoglobin induction and screen for therapeutic compounds
Thijs C. J. Verheul, Nynke Gillemans, Kerstin Putzker, Rezin Majied, Tingyue Li, Memnia Vasiliou, Bert Eussen, Annelies de Klein, Wilfred F. J. van IJcken, Emile van den Akker, Marieke von Lindern, Joe Lewis, Ulrike Uhrig, Yukio Nakamura, Thamar van Dijk, Sjaak Philipsen,

First published: 06 August 2024
REVIEW ARTICLE
Open Access

oa

Fibrinogen-like 1: A hepatokine linking liver physiology to hematology
Jean Personnaz, Hervé Guillou, Léon Kautz,

First published: 04 July 2024

Collections: Reviews
LETTER
Open Access

oa

A single-center cohort study of patients with hereditary spherocytosis in Central Europe reveals a high frequency of novel disease-causing genotypes
Leo Kager, Raúl Jimenez-Heredia, Petra Zeitlhofer, Wolfgang Novak, Sebastian K. Eder, Anna Segarra-Roca, Alexandra Frohne, Karin Nebral, Matthias Haimel, René Geyeregger, Katharina Roetzer-Londgin, Oskar A. Haas, Kaan Boztug,

First published: 26 January 2024
Letter
Open Access

oa

Burden of Aging: Health Outcomes Among Adolescents and Young Adults With Sickle Cell Disease
Kristen E. Howell, Norma Pugh, Jennifer Longoria, Nirmish Shah, Abdullah Kutlar, Victor R. Gordeuk, Allison A. King, Jeffrey Glassberg, Mariam Kayle, Cathy Melvin, Marsha Treadwell, Jane S. Hankins, Jerlym S. Porter, Sickle Cell Disease Implementation Consortium,

First published: 13 July 2023
Letter
Open Access

oa

IthaPhen: An Interactive Database of Genotype-Phenotype Data for Hemoglobinopathies
Maria Xenophontos, Anna Minaidou, Coralea Stephanou, Stella Tamana, Marina Kleanthous, Petros Kountouris,

First published: 22 June 2023
Review Article
Open Access

oa

Sutimlimab for the Treatment of Cold Agglutinin Disease
Sigbjørn Berentsen,

First published: 02 May 2023

Collections: Reviews

Graphical Abstract
Letter
Open Access

oa

Effect of Eculizumab on Iron Metabolism in Transfusion-independent Patients With Paroxysmal Nocturnal Hemoglobinuria
Charlotte C.M. Schaap, Saskia E.M. Schols, Frank W.M.B. Preijers, Emiel de Jonge, Coby M.M. Laarakkers, Joop H. Jansen, Nicole M.A. Blijlevens, Dorine W. Swinkels, Saskia M.C. Langemeijer,

First published: 19 April 2023
Article
Open Access

oa

The Increase in Hemoglobin Concentration With Altitude Differs Between World Regions and Is Less in Children Than in Adults
Heimo Mairbäurl, Samuel Kilian, Svenja Seide, Martina U. Muckenthaler, Max Gassmann, Rukundo K. Benedict,

First published: 05 April 2023

Graphical Abstract
Article
Open Access

oa

In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell–Related Injury
Enrica Federti, Alessandro Matte, Antonio Recchiuti, Francesca Garello, Alessandra Ghigo, Wassim El Nemer, Enzo Terreno, Angela Amoresano, Domenico Mattoscio, Franco Turrini, Christophe Lebouef, Anne Janin, Antonella Pantaleo, Roberta Russo, Mickael Marin, Iana Iatcencko, Veronica Riccardi, Angela Siciliano, Achille Iolascon, Carlo Brugnara, Lucia De Franceschi,

First published: 28 February 2023

Graphical Abstract
Comment
Open Access

oa

Challenges and Opportunities of Precision Medicine in Sickle Cell Disease: Novel European Approach by GenoMed4All Consortium and ERN-EuroBloodNet
Anna Collado, Maria Paola Boaro, Sigrid van der Veen, Amira Idrizovic, Bart J. Biemond, David Beneitez Pastor, Ana Ortuño, Elena Cela, Anna Ruiz-Llobet, Pablo Bartolucci, Marianne de Montalembert, Gastone Castellani, Riccardo Biondi, Renzo Manara, Tiziana Sanavia, Piero Fariselli, Petros Kountouris, Marina Kleanthous, Federico Alvarez, Santiago Zazo, Raffaella Colombatti, Eduard J. van Beers, María del Mar Mañú-Pereira,

First published: 22 February 2023
Letter
Open Access

oa

Excessive Erythrocytosis Is Not Associated With Altered Iron Homeostasis in Men From the World's Highest City
Gaetano Cairo, Benoit Champigneulle, Margherita Correnti, Elena Gammella, Stefania Recalcati, Domenico Girelli, Annalisa Castagna, Anne-Kristine Meinild Lundby, Ivan Hancco, Carole Chirica, Dorra Guergour, Laura Oberholzer, Emeric Stauffer, Carsten Lundby, Aurélien Pichon, Julien V Brugniaux, Stéphane Doutreleau, Samuel Verges, Paul Robach,

First published: 22 February 2023
Perspective
Open Access

oa

Untreated Anemia in Nontransfusion-dependent β-thalassemia: Time to Sound the Alarm
Khaled M. Musallam, Ali T. Taher, Maria Domenica Cappellini, Olivier Hermine, Kevin H. M. Kuo, Sujit Sheth, Vip Viprakasit, John B. Porter,

First published: 15 November 2022
Letter
Open Access

oa

Iron-dependent BMP6 Regulation in Liver Sinusoidal Endothelial Cells Is Instructed by Hepatocyte-derived Secretory Signals
Silvia Colucci, Sandro Altamura, Oriana Marques, Katja Müdder, Anand R. Agarvas, Matthias W. Hentze, Martina U. Muckenthaler,

First published: 27 September 2022
Letter
Open Access

oa

Ferritin Increase in Hemochromatosis Subjects After Discontinuing Their Regular Maintenance Treatment: A Longitudinal Analysis Performed During the COVID-19 Imposed Hospital Lockdown
Maria P. Coutinho, Maria José Teles, Graça Melo, Marta Lopes, Delfim Duarte, Tiago L. Duarte, Júlia Reis, Ana Cláudia Martins, José Carlos Oliveira, Graça Porto,

First published: 23 August 2022
Guideline Article—Expert opinion
Open Access

oa

2021 Thalassaemia International Federation Guidelines for the Management of Transfusion-dependent Thalassemia
Dimitrios Farmakis, John Porter, Ali Taher, Maria Domenica Cappellini, Michael Angastiniotis, Androulla Eleftheriou, for the 2021 TIF Guidelines Taskforce, John Porter, Ali Taher, Maria Domenica Cappellini, Dimitrios Farmakis, Ali Alassaf, Michael Angastiniotis, Emanuele Angelucci, Yesim Aydinok, Rayan Bou-Fakhredin Rayan, Loris Brunetta, Maria Domenica Cappellini, George Constantinou, Shahina Daar, Vincenzo De Sanctis, Geoffrey Dusheiko, Riyad Elbard, Androulla Eleftheriou, Perla Eleftheriou, Panos Englezos, Dimitrios Farmakis, Dru Haines, Faiez N Hattab, George Kaltsounis, Antonios Kattamis, John Koskinas, Navdeep Kumar, Andreas Kulozik, Andreas Kyriakou, Aurelio Maggio, Roanna Maharai, Lauren Mednick, Eleni Michalaki, Wendy Murphy, Lena Oevermann, Raffaella Origa, Penelope-Georgia Papayanni, Constantina Politis, John Porter, Farukh Shah, Anton Skafi, Nikos Skordis, Pietro Sodani, Ashraf Soliman, Seni Subair, Ali Taher, Maria Tampaki, Sara Trompeter, Shobha Tuli, Malcolm Walker, Robert Yamashita, Evangelia Yannaki, Anne Yardumian,

First published: 29 July 2022

Collections: Guidelines
Guideline Article—Consensus based
Open Access

oa

The Use of Next-generation Sequencing in the Diagnosis of Rare Inherited Anaemias: A Joint BSH/EHA Good Practice Paper
Noémi B. A. Roy, Lydie Da Costa, Roberta Russo, Paola Bianchi, Maria del Mar Mañú-Pereira, Elisa Fermo, Immacolata Andolfo, Barnaby Clark, Melanie Proven, Mayka Sanchez, Richard van Wijk, Bert van der Zwaag, Mark Layton, David Rees, Achille Iolascon, British Society for Haematology and the European Hematology Association,

First published: 06 June 2022

Collections: Guidelines
Letter
Open Access

oa

IRE-dependent Regulation of Intestinal Dmt1 Prevails During Chronic Dietary Iron Deficiency but is Dispensable in Conditions of Acute Erythropoietic Stress
Maria Qatato, Michael Bonadonna, Gaël Palais, Alina Ertl, Gabriele Schmidt, Maria Polycarpou-Schwarz, Zoubida Karim, Bruno Galy,

First published: 16 February 2022
Correction Notice
Open Access

oa

Correction Notice: Modeling Benefits, Costs, and Affordability of a Novel Gene Therapy in Hemophilia A
First published: 15 February 2022
Letter
Open Access

oa

Hfe Is Highly Expressed in Liver Sinusoidal Endothelial Cells But Is Not Needed to Maintain Systemic Iron Homeostasis In Vivo
Silvia Colucci, Katja Müdder, Martina U. Muckenthaler, Sandro Altamura,

First published: 20 December 2021

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oa

The oral ferroportin inhibitor vamifeport prevents liver iron overload in a mouse model of hemochromatosis

Graphical Abstract

oa

A cellular reporter system to evaluate endogenous fetal hemoglobin induction and screen for therapeutic compounds

oa

Fibrinogen-like 1: A hepatokine linking liver physiology to hematology

oa

A single-center cohort study of patients with hereditary spherocytosis in Central Europe reveals a high frequency of novel disease-causing genotypes

oa

Burden of Aging: Health Outcomes Among Adolescents and Young Adults With Sickle Cell Disease

oa

IthaPhen: An Interactive Database of Genotype-Phenotype Data for Hemoglobinopathies

oa

Sutimlimab for the Treatment of Cold Agglutinin Disease

Graphical Abstract

oa

Effect of Eculizumab on Iron Metabolism in Transfusion-independent Patients With Paroxysmal Nocturnal Hemoglobinuria

oa

The Increase in Hemoglobin Concentration With Altitude Differs Between World Regions and Is Less in Children Than in Adults

Graphical Abstract

oa

In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell–Related Injury

Graphical Abstract

oa

Challenges and Opportunities of Precision Medicine in Sickle Cell Disease: Novel European Approach by GenoMed4All Consortium and ERN-EuroBloodNet

oa

Excessive Erythrocytosis Is Not Associated With Altered Iron Homeostasis in Men From the World's Highest City

oa

Untreated Anemia in Nontransfusion-dependent β-thalassemia: Time to Sound the Alarm

oa

Iron-dependent BMP6 Regulation in Liver Sinusoidal Endothelial Cells Is Instructed by Hepatocyte-derived Secretory Signals

oa

Ferritin Increase in Hemochromatosis Subjects After Discontinuing Their Regular Maintenance Treatment: A Longitudinal Analysis Performed During the COVID-19 Imposed Hospital Lockdown

oa

2021 Thalassaemia International Federation Guidelines for the Management of Transfusion-dependent Thalassemia

oa

The Use of Next-generation Sequencing in the Diagnosis of Rare Inherited Anaemias: A Joint BSH/EHA Good Practice Paper

oa

IRE-dependent Regulation of Intestinal Dmt1 Prevails During Chronic Dietary Iron Deficiency but is Dispensable in Conditions of Acute Erythropoietic Stress

oa

Correction Notice: Modeling Benefits, Costs, and Affordability of a Novel Gene Therapy in Hemophilia A

oa

Hfe Is Highly Expressed in Liver Sinusoidal Endothelial Cells But Is Not Needed to Maintain Systemic Iron Homeostasis In Vivo

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oa The oral ferroportin inhibitor vamifeport prevents liver iron overload in a mouse model of hemochromatosis

Graphical Abstract

oa A cellular reporter system to evaluate endogenous fetal hemoglobin induction and screen for therapeutic compounds

oa Fibrinogen-like 1: A hepatokine linking liver physiology to hematology

oa A single-center cohort study of patients with hereditary spherocytosis in Central Europe reveals a high frequency of novel disease-causing genotypes

oa Burden of Aging: Health Outcomes Among Adolescents and Young Adults With Sickle Cell Disease

oa IthaPhen: An Interactive Database of Genotype-Phenotype Data for Hemoglobinopathies

oa Sutimlimab for the Treatment of Cold Agglutinin Disease

Graphical Abstract

oa Effect of Eculizumab on Iron Metabolism in Transfusion-independent Patients With Paroxysmal Nocturnal Hemoglobinuria

oa The Increase in Hemoglobin Concentration With Altitude Differs Between World Regions and Is Less in Children Than in Adults

Graphical Abstract

oa In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell–Related Injury

Graphical Abstract

oa Challenges and Opportunities of Precision Medicine in Sickle Cell Disease: Novel European Approach by GenoMed4All Consortium and ERN-EuroBloodNet

oa Excessive Erythrocytosis Is Not Associated With Altered Iron Homeostasis in Men From the World's Highest City

oa Untreated Anemia in Nontransfusion-dependent β-thalassemia: Time to Sound the Alarm

oa Iron-dependent BMP6 Regulation in Liver Sinusoidal Endothelial Cells Is Instructed by Hepatocyte-derived Secretory Signals

oa Ferritin Increase in Hemochromatosis Subjects After Discontinuing Their Regular Maintenance Treatment: A Longitudinal Analysis Performed During the COVID-19 Imposed Hospital Lockdown

oa 2021 Thalassaemia International Federation Guidelines for the Management of Transfusion-dependent Thalassemia

oa The Use of Next-generation Sequencing in the Diagnosis of Rare Inherited Anaemias: A Joint BSH/EHA Good Practice Paper

oa IRE-dependent Regulation of Intestinal Dmt1 Prevails During Chronic Dietary Iron Deficiency but is Dispensable in Conditions of Acute Erythropoietic Stress

oa Correction Notice: Modeling Benefits, Costs, and Affordability of a Novel Gene Therapy in Hemophilia A

oa Hfe Is Highly Expressed in Liver Sinusoidal Endothelial Cells But Is Not Needed to Maintain Systemic Iron Homeostasis In Vivo

oa

The oral ferroportin inhibitor vamifeport prevents liver iron overload in a mouse model of hemochromatosis

oa

A cellular reporter system to evaluate endogenous fetal hemoglobin induction and screen for therapeutic compounds

oa

Fibrinogen-like 1: A hepatokine linking liver physiology to hematology

oa

A single-center cohort study of patients with hereditary spherocytosis in Central Europe reveals a high frequency of novel disease-causing genotypes

oa

Burden of Aging: Health Outcomes Among Adolescents and Young Adults With Sickle Cell Disease

oa

IthaPhen: An Interactive Database of Genotype-Phenotype Data for Hemoglobinopathies

oa

Sutimlimab for the Treatment of Cold Agglutinin Disease

oa

Effect of Eculizumab on Iron Metabolism in Transfusion-independent Patients With Paroxysmal Nocturnal Hemoglobinuria

oa

The Increase in Hemoglobin Concentration With Altitude Differs Between World Regions and Is Less in Children Than in Adults

oa

In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell–Related Injury

oa

Challenges and Opportunities of Precision Medicine in Sickle Cell Disease: Novel European Approach by GenoMed4All Consortium and ERN-EuroBloodNet

oa

Excessive Erythrocytosis Is Not Associated With Altered Iron Homeostasis in Men From the World's Highest City

oa

Untreated Anemia in Nontransfusion-dependent β-thalassemia: Time to Sound the Alarm

oa

Iron-dependent BMP6 Regulation in Liver Sinusoidal Endothelial Cells Is Instructed by Hepatocyte-derived Secretory Signals

oa

Ferritin Increase in Hemochromatosis Subjects After Discontinuing Their Regular Maintenance Treatment: A Longitudinal Analysis Performed During the COVID-19 Imposed Hospital Lockdown

oa

2021 Thalassaemia International Federation Guidelines for the Management of Transfusion-dependent Thalassemia

oa

The Use of Next-generation Sequencing in the Diagnosis of Rare Inherited Anaemias: A Joint BSH/EHA Good Practice Paper

oa

IRE-dependent Regulation of Intestinal Dmt1 Prevails During Chronic Dietary Iron Deficiency but is Dispensable in Conditions of Acute Erythropoietic Stress

oa

Correction Notice: Modeling Benefits, Costs, and Affordability of a Novel Gene Therapy in Hemophilia A

oa

Hfe Is Highly Expressed in Liver Sinusoidal Endothelial Cells But Is Not Needed to Maintain Systemic Iron Homeostasis In Vivo