The objective of the study was to use targeted metabolomics following exercise to evaluate alterations in metabolic pathways in ambulatory adolescents and young adults with cerebral palsy (CP) compared to those with typical development. Our study found that funcional capacity and mobility (top left) in these individuals was associated with metabolite abundance only in individuals with CP.
This original article is commented by Sutehall on pages560–561 of this issue.
Congenital anomalies are more common in people with cerebral palsy (CP) compared to the non-CP population. In our population-based study, 23.4% of persons with CP had a congenital anomaly (CA) but 7% of the cohort had anomalies that were unlikely to be pathogenic. Cerebral anomalies and developmental causal pathways comprised 14% of CP whereas congenital anomalies and pathways involving destructive brain insults accounted for less than 3% of CP.
This study aimed to refine the Gross Motor Family Report (GM-FR) using parent input and to evaluate its psychometric properties. The active participation of families in the development of the GM-FR facilitated creation of a family-friendly instrument. This study provides strong evidence of reliability and validity to support use of the GM-FR in clinical practice and research to assess gross motor performance of children and adolescents with cerebral palsy aged 2 to 18 years.
This original article is commented by Ünes on pages 148–149 of this issue.
Portuguese translation of this Original Article is available in the online issue.
Ten priorities have been identified by adolescents with physical disability to improve participation in physical activity. The priorities will help inform the design of future physical activity interventions. Acceptance within the social context was highlighted for physical activity participation and personal preference for fun and enjoyment was highly valued.
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