Fibrodysplasia Ossificans Progressiva and Heterotopic Ossification

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3 November 2023
3 November 2023
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Open Access

Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development

Marjorie Salga,  Selwin G Samuel,  Hsu-Wen Tseng,  Laure Gatin,  Dorothée Girard,  Bastien Rival,  Valérie Barbier,  Kavita Bisht,  Svetlana Shatunova,  Charlotte Debaud,  Ingrid G Winkler,  Julie Paquereau,  Aurélien Dinh,  Guillaume Genêt,  Sébastien Kerever,  Paer-Sélim Abback,  Sébastien Banzet,  François Genêt,  Jean-Pierre Lévesque,  Kylie A Alexander, 
Open Access

Reduction of New Heterotopic Ossification (HO) in the Open-Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP)

Robert J. Pignolo,  Edward C. Hsiao,  Mona Al Mukaddam,  Geneviève Baujat,  Staffan K. Berglund,  Matthew A. Brown,  Angela M. Cheung,  Carmen De Cunto,  Patricia Delai,  Nobuhiko Haga,  Peter Kannu,  Richard Keen,  Kim-Hanh Le Quan Sang,  Edna E. Mancilla,  Rose Marino,  Andrew Strahs,  Frederick S. Kaplan, 
Free Access

Reduced GS Domain Serine/Threonine Requirements of Fibrodysplasia Ossificans Progressiva Mutant Type I BMP Receptor ACVR1 in the Zebrafish

Robyn S. Allen,  William D. Jones,  Maya Hale,  Bailey N. Warder,  Eileen M. Shore,  Mary C. Mullins, 
Free Access

Shedding Light on Bone Morphogenetic Protein (BMP) Signaling Modifiers to Modulate Fibrodysplasia Ossificans Progressiva Severity

Antonella Forlino, 
Open Access

Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1R206H-Specific Human Cellular and Zebrafish Models

Kelly L. Wentworth,  Robert L. Lalonde,  Jay C. Groppe,  Niambi Brewer,  Tania Moody,  Steven Hansberry,  Kimberly E. Taylor,  Eileen M. Shore,  Frederick S. Kaplan,  Robert J. Pignolo,  Pamela C. Yelick,  Edward C. Hsiao, 
Open Access

Overexpression of Wild-Type ACVR1 in Fibrodysplasia Ossificans Progressiva Mice Rescues Perinatal Lethality and Inhibits Heterotopic Ossification

Masakazu Yamamoto,  Sean J Stoessel,  Shoko Yamamoto,  David J Goldhamer, 
Free Access

Activating EGFR Signaling Attenuates Osteoarthritis Development Following Loading Injury in Mice

Tao Gui,  Yulong Wei,  Lijun Luo,  Jun Li,  Leilei Zhong,  Lutian Yao,  Frank Beier,  Charles L. Nelson,  Andrew Tsourkas,  X. Sherry Liu,  Motomi Enomoto-Iwamoto,  Feifan Yu,  Zhiliang Cheng,  Ling Qin,