Volume 39, Issue 11 pp. 1042-1046
Case Report

Metastatic small cell neuroendocrine carcinoma of the breast

Alan S. Boyd

Corresponding Author

Alan S. Boyd

Department of Medicine (Dermatology), Vanderbilt University, Nashville, TN, USA

Department of Pathology, Vanderbilt University, Nashville, TN, USA

Alan S. Boyd, MD,

719 Thompson Lane, Suite 26300, Nashville, TN 37204, USA

Tel: +1 615 322 6485

Fax: +1 615 343 2591

e-mail: [email protected]

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Benjamin B. Hayes

Benjamin B. Hayes

Spring Hill Dermatology and Allergy Clinic, Spring Hill, TN, USA

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First published: 09 July 2012
Citations: 12

Abstract

Cutaneous metastases from internal malignancies in women overwhelmingly emanate from the breast and typically exhibit features of an adenocarcinoma, although other histopathologic patterns may also be seen. Neuroendocrine breast carcinoma represents an uncommon variant of mammary carcinoma with fewer than 40 cases of the small cell subcategory reported. As with other small cell carcinomas, they may exhibit Merkel cell-like features and appropriate diagnosis of these tumor deposits often turns on clinical history and an appropriate immunohistochemical profile. Herein, we report the first known patient with cutaneous metastases from a small cell neuroendocrine breast carcinoma.

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