Volume 21, Issue 1 pp. 34-37

Volumetric Asymmetry and Differential Aging Effect of the Human Caudate Nucleus in Normal Individuals: A Prospective MR Imaging Study

Koji Yamashita MD, PhD,

Koji Yamashita MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Takashi Yoshiura MD, PhD,

Takashi Yoshiura MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Akio Hiwatashi MD,

Akio Hiwatashi MD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Tomoyuki Noguchi MD, PhD,

Tomoyuki Noguchi MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Osamu Togao MD, PhD,

Osamu Togao MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Yukihisa Takayama MD,

Yukihisa Takayama MD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Eiki Nagao MD,

Eiki Nagao MD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Hironori Kamano MD,

Hironori Kamano MD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Masamitsu Hatakenaka MD, PhD,

Masamitsu Hatakenaka MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Hiroshi Honda MD, PhD,

Hiroshi Honda MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Koji Yamashita MD, PhD,

Koji Yamashita MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Takashi Yoshiura MD, PhD,

Takashi Yoshiura MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Akio Hiwatashi MD,

Akio Hiwatashi MD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Tomoyuki Noguchi MD, PhD,

Tomoyuki Noguchi MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Osamu Togao MD, PhD,

Osamu Togao MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Yukihisa Takayama MD,

Yukihisa Takayama MD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Eiki Nagao MD,

Eiki Nagao MD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Hironori Kamano MD,

Hironori Kamano MD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Masamitsu Hatakenaka MD, PhD,

Masamitsu Hatakenaka MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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Hiroshi Honda MD, PhD,

Hiroshi Honda MD, PhD

From the Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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First published: 28 December 2010

https://doi.org/10.1111/j.1552-6569.2009.00403.x

Citations: 30

Correspondence: Address correspondence to Koji Yamashita, MD, Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. E-mail: [email protected].

J Neuroimaging 2011;21:34-37.

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Abstract

ABSTRACT

PURPOSE

The purpose of this study was to examine interhemispheric asymmetry in volume of the caudate nucleus and its age dependency.

METHODS

High-resolution T1-weighted brain magnetic resonance (MR) images were obtained for each subject using a 3-dimensional fast field-echo pulse sequence. The volumes of the bilateral caudate nuclei on MR images were measured using an automated method. Right-to-left comparison was made using paired t-test. Age-related change of right-to-left volume ratio (R/L ratio) was examined using Pearson's correlation coefficient.

RESULTS

Fifty healthy right-handed Japanese male subjects (age 12 to 67 years, mean 39.6 years) were involved in this study. The volume of right caudate nucleus was larger than the left in 48 of 50 subjects (P < .001). R/L ratio increased with age (r= .420, P < .01).

CONCLUSIONS

Our results confirmed the rightward volumetric asymmetry of caudate nucleus in right-handed individuals, and revealed that this asymmetry becomes notable with age.

References

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Citing Literature

Volume21, Issue1

January 2011

Pages 34-37

Volumetric Asymmetry and Differential Aging Effect of the Human Caudate Nucleus in Normal Individuals: A Prospective MR Imaging Study

Abstract

ABSTRACT

PURPOSE

METHODS

RESULTS

CONCLUSIONS

References

Citing Literature

References

Information

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Volumetric Asymmetry and Differential Aging Effect of the Human Caudate Nucleus in Normal Individuals: A Prospective MR Imaging Study

Abstract

ABSTRACT

PURPOSE

METHODS

RESULTS

CONCLUSIONS

References

Citing Literature

References

Related

Information