Direct duplication of the Y chromosome with normal phenotype – incidental finding in two cases
L.-C. Kuan
Department of Obstetrics and Gynecology, Kuo General Hospital, Tainan, Taiwan
Search for more papers by this authorM.-T. Su
Department of Obstetrics and Gynecology, National Cheng Kung University Hospital and College of Medicine, Tainan, Taiwan
Search for more papers by this authorP.-L. Kuo
Department of Obstetrics and Gynecology, National Cheng Kung University Hospital and College of Medicine, Tainan, Taiwan
This author has equal contribution as the corresponding author.Search for more papers by this authorCorresponding Author
T.-C. Kuo
Department of Obstetrics and Gynecology, Kuo General Hospital, Tainan, Taiwan
Correspondence
Dr. Tsung-Cheng Kuo, Department of Obstetrics and Gynecology, Kuo General Hospital. No. 22, Sec.2, Minsheng Road, Tainan City 700, Taiwan.
Tel.: +886-6-222-1111
Fax: +886-6-225-0011
E-mail: [email protected]
Search for more papers by this authorL.-C. Kuan
Department of Obstetrics and Gynecology, Kuo General Hospital, Tainan, Taiwan
Search for more papers by this authorM.-T. Su
Department of Obstetrics and Gynecology, National Cheng Kung University Hospital and College of Medicine, Tainan, Taiwan
Search for more papers by this authorP.-L. Kuo
Department of Obstetrics and Gynecology, National Cheng Kung University Hospital and College of Medicine, Tainan, Taiwan
This author has equal contribution as the corresponding author.Search for more papers by this authorCorresponding Author
T.-C. Kuo
Department of Obstetrics and Gynecology, Kuo General Hospital, Tainan, Taiwan
Correspondence
Dr. Tsung-Cheng Kuo, Department of Obstetrics and Gynecology, Kuo General Hospital. No. 22, Sec.2, Minsheng Road, Tainan City 700, Taiwan.
Tel.: +886-6-222-1111
Fax: +886-6-225-0011
E-mail: [email protected]
Search for more papers by this authorSummary
Structural rearrangement in the Y chromosome is closely involved in spermatogenesis. However, several Y chromosome variants may have no deleterious effects on male reproduction. Here, we report two cases of Y chromosomal duplication from incidental findings. Their FISH analysis revealed direct duplication of large segments of short and long arms of the Y chromosome. Nearly two intact Y chromosomes were carried in these two cases with normal phenotype.
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