Cutaneous sarcoidal granulomas developing after facial cosmetic filler in a patient with newly diagnosed systemic sarcoidosis

Erratum. Notice is given that it has been drawn to the attention of the journal that the dermal filler used in this case was erroneously identified as Artecoll^®. The authors submitted this article in good faith on the strength of documentary evidence that Artecoll^® had been used. Subsequent expert opinion indicates that the particles seen in the skin biopsy are not Artecoll^®.

There is no implication in the article or its title that the dermal filler caused systemic sarcoidosis. The authors stated that the filler (unknown) has the potential to act as a stimulus for cutaneous sarcoidal granulomas in susceptible patients.

The authors and editor of the journal wish to apologise to Artes Medical and to reassure readers and Artes Medical that these erroneous data will not be reported in their future work.

Summary

Artecoll^® is a recently developed permanent synthetic cosmetic filler substance, composed of 80% bovine collagen and 20% polymethylacrylate (PMMA) microspheres of 32–40 μm in diameter. It is used for the augmentation of deep wrinkles and is to be injected subdermally. We report the development of granulomas at the site of Artecoll injections in the face in a 48-year-old woman who had pulmonary sarcoidosis. There were features consistent of both sarcoid and foreign-body granuloma, typical of those reported previously with Artecoll. We postulate that the PMMA foreign material contained within Artecoll acted as a stimulus for the development of the cutaneous sarcoid granulomas.