Volume 35, Issue 12 pp. 2104-2105
CASE REPORTS Section Editor - Brian D. Hoit, MD

Bioprosthetic mitral valve thrombosis and subsequent obstruction from non-Hodgkins lymphoma despite anticoagulation

Mohammed Y Khanji MBBCh, PhD

Corresponding Author

Mohammed Y Khanji MBBCh, PhD

University Hospital Wales, Cardiff, UK

Barts Health NHS Trust, Newham University Hospital, London, UK

Correspondence

Dr Mohammed Y Khanji, Newham University Hospital, Barts Health NHS Trust, London, UK.

Email: [email protected]

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Richard Wheeler MBChB

Richard Wheeler MBChB

University Hospital Wales, Cardiff, UK

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Omar Nawaytou MD

Omar Nawaytou MD

University Hospital Wales, Cardiff, UK

Department of Cardiac Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK

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Azeem S Sheikh MBBS, FCPS, MRCP, PGCert (Med Edu)

Azeem S Sheikh MBBS, FCPS, MRCP, PGCert (Med Edu)

University Hospital Wales, Cardiff, UK

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First published: 15 October 2018

Abstract

Malignancy can cause a hypercoagulable state, it rarely causes prosthetic valve thrombosis, with only limited cases reports due to lymphoma. Although no standardised approach for treatment exists, the combination of early diagnosis, surgical intervention and adjuvant chemotherapy are likely to provide the best chances of survival. We describe an interesting case of a bioprosthetic mitral valve thrombosis leading to valve obstruction in a patient with non-Hodgkin's lymphoma despite being on anticoagulation.

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