Atypical eumycetoma caused by Phialophora parasitica successfully treated with itraconazole and flucytosine
Corresponding Author
S.V. HOOD
Department of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
S.V.Hood, Monsall Unit, NMGH, Delaunay's Road, Crumpsall, Manchester M8 6RL, U.K.Search for more papers by this authorC.B. MOORE
Department of Microbiology and Section of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
Search for more papers by this authorJ.S. CHEESBROUGH
Department of Microbiology and Section of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
Search for more papers by this authorA. MENE
Department of Pathology, Blackburn Royal Infirmary, Bolton Road, Blackburn BB23LR, U.K.
Search for more papers by this authorD.W. DENNING
Department of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
Department of Section of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
Search for more papers by this authorCorresponding Author
S.V. HOOD
Department of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
S.V.Hood, Monsall Unit, NMGH, Delaunay's Road, Crumpsall, Manchester M8 6RL, U.K.Search for more papers by this authorC.B. MOORE
Department of Microbiology and Section of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
Search for more papers by this authorJ.S. CHEESBROUGH
Department of Microbiology and Section of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
Search for more papers by this authorA. MENE
Department of Pathology, Blackburn Royal Infirmary, Bolton Road, Blackburn BB23LR, U.K.
Search for more papers by this authorD.W. DENNING
Department of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
Department of Section of Infectious Diseases, Department of Medicine. The University of Manchester, Hope Hospital, Eccles Old Road, Salford, M6 8HD, U.K.
Search for more papers by this authorSummary
Phialophora species are occasional pathogens causing subcutaneous and invasive disease. We report the first case of eumycetoma caused by P. parasitica in an otherwise healthy U.K. resident who visited India. She failed to respond to surgical excision and itraconazole. 400 mg daily, but responded to itraconazole, 400 mg daily, and flucytosine, 1 g three times daily, lor 12 months. In vitro susceptibility testing predicted a response.
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