Synthesis and Anticancer Activity of New Substituted Pyrazoles and Their Derived 1,2,4-Triazoles and Sugar Derivatives
Eman M. Flefel
Department of Photochemistry, National Research Centre, Cairo, Egypt
Search for more papers by this authorWaled A. Tantawy
Department of Photochemistry, National Research Centre, Cairo, Egypt
Search for more papers by this authorCorresponding Author
Wael A. El-Sayed
Department of Photochemistry, National Research Centre, Cairo, Egypt
E-mail: [email protected]
Search for more papers by this authorHayam H. Sayed
Department of Photochemistry, National Research Centre, Cairo, Egypt
Search for more papers by this authorNahed M. Fathy
Department of Photochemistry, National Research Centre, Cairo, Egypt
Search for more papers by this authorEman M. Flefel
Department of Photochemistry, National Research Centre, Cairo, Egypt
Search for more papers by this authorWaled A. Tantawy
Department of Photochemistry, National Research Centre, Cairo, Egypt
Search for more papers by this authorCorresponding Author
Wael A. El-Sayed
Department of Photochemistry, National Research Centre, Cairo, Egypt
E-mail: [email protected]
Search for more papers by this authorHayam H. Sayed
Department of Photochemistry, National Research Centre, Cairo, Egypt
Search for more papers by this authorNahed M. Fathy
Department of Photochemistry, National Research Centre, Cairo, Egypt
Search for more papers by this authorAbstract
New substituted pyrazole, thiazole, and 1,2,4-triazole derivatives were synthesized. The sugar hydrazones, their acetylated derivatives as well as their derived acyclic C-nucleoside analogs, and the thioglycosides of the 1,2,4-traizole derivatives were also prepared. The antitumor activity of some of the synthesized compounds were studied, and a number of the tested compounds showed significant activities.
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