Self-Assembling Neodymium/Sodium Heterobimetallic Asymmetric Catalyst Confined in a Carbon Nanotube Network†
Takanori Ogawa
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.html
Search for more papers by this authorCorresponding Author
Dr. Naoya Kumagai
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.html
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.htmlSearch for more papers by this authorCorresponding Author
Prof. Dr. Masakatsu Shibasaki
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.html
JST, ACT-C, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan)
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.htmlSearch for more papers by this authorTakanori Ogawa
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.html
Search for more papers by this authorCorresponding Author
Dr. Naoya Kumagai
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.html
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.htmlSearch for more papers by this authorCorresponding Author
Prof. Dr. Masakatsu Shibasaki
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.html
JST, ACT-C, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan)
Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021 (Japan) http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/index_e.htmlSearch for more papers by this authorThis work was financially supported by KAKENHI (20229001 and 24106745) from JSPS and MEXT, and JST, ACT-C. N.K. thanks the Suzuken Memorial Foundation for financial support. We thank Prof. Dr. Magnus Rueping for fruitful discussions.
Graphical Abstract
Confined cat works better: A self-assembling heterobimetallic catalyst, comprised of a Nd/Na/amide ligand confined in an entangled multiwalled carbon nanotube (MWNT) network, outperforms the unconfined catalyst in anti-selective catalytic asymmetric nitroaldol reactions. The confined catalyst could be used repeatedly through simple filtration, and was applied to a concise enantioselective synthesis of anacetrapib.
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