Chapter 34
Biosynthetic Pathway Engineering Strategies
Claudia Schmidt-Dannert,
Alexander Pisarchik,
Claudia Schmidt-Dannert
Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 1479 Gortner Avenue, St. Paul, MN 55108, USA
Search for more papers by this authorAlexander Pisarchik
Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 1479 Gortner Avenue, St. Paul, MN 55108, USA
Search for more papers by this authorClaudia Schmidt-Dannert,
Alexander Pisarchik,
Claudia Schmidt-Dannert
Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 1479 Gortner Avenue, St. Paul, MN 55108, USA
Search for more papers by this authorAlexander Pisarchik
Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 1479 Gortner Avenue, St. Paul, MN 55108, USA
Search for more papers by this authorBook Editor(s):Prof. Dr. Stefan Lutz,
Prof. Dr. Uwe T. Bornscheuer,
Prof. Dr. Stefan Lutz
Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, USA
Search for more papers by this authorProf. Dr. Uwe T. Bornscheuer
Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, Greifswald University, Felix-Hausdorff-Str. 4, 17487 Greifswald, Germany
Search for more papers by this authorFirst published: 12 November 2008
Summary
This chapter contains sections titled:
-
Introduction
-
Initial Pathway Design
-
Optimization of the Precursor Supply
-
Engineering of Control Loops
-
Engineering of Alternative Precursor Routes
-
Balancing Gene Expression Levels and Activities of Metabolic Enzymes
-
Metabolic Network Integration and Optimization
-
Engineering Pathways for the Production of Diverse Compounds
-
Future Perspectives
-
Abbreviations
-
References
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