Trauma exposure is relatively common, with men being more likely to be experience a trauma than women. Clinicians need to be aware that only a small minority of these trauma-exposed individuals go on to develop post-traumatic stress disorder (PTSD), with women being almost twice as likely as men to have PTSD at some point during their lifetime. Emotional processing theory suggests that pathological fear structures must be activated and modified for PTSD symptoms to decrease. In individuals with PTSD, sensory-bound representations (S-reps) are strongly encoded while contextual-bound representations (C-reps) are weakly encoded, making the S-reps difficult to modify because of verbal inaccessibility. Virtual reality exposure therapy is a variant of exposure that presents multisensory fear-relevant stimuli via a virtual environment, usually through a motion-sensitive head-mounted instrument. Most PTSD randomized control trials (RCTs) do not exclude suicidality but do exclude patients with a serious attempt in the past three months, active suicidal intent.