Chapter 18
Blood-Inhabiting Protozoans: Piroplasms (Theileria spp., Cytauxzoon spp., and Babesia spp.)
A. Alan Kocan,
Kenneth A. Waldrup,
A. Alan Kocan
Search for more papers by this authorKenneth A. Waldrup
Search for more papers by this authorA. Alan Kocan,
Kenneth A. Waldrup,
A. Alan Kocan
Search for more papers by this authorKenneth A. Waldrup
Search for more papers by this authorBook Editor(s):William M. Samuel Ph.D.,
Margo J. Pybus Ph.D.,
A. Alan Kocan Ph.D.,
William M. Samuel Ph.D.
Professor
Department of Biological Sciences at the University of Alberta
Search for more papers by this authorMargo J. Pybus Ph.D.
Wildlife Disease Specialist
Alberta Natural Resources Service-Fisheries and Wildlife
Search for more papers by this authorA. Alan Kocan Ph.D.
Professor of Pathobiology
College of Veterinary Medicine at Oklahoma State University
Search for more papers by this authorSummary
This chapter contains section titled:
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Theileria SPP. (Theileriosis) AND Cytauxzoon SPP. (Cytauxzoonosis).
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Babesia SPP. (Babesiosis)
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Literature Cited
Literature Cited
- Anderson, J. F., L., Magnarelli, and A. Sulzer. 1981. Raccoon babesiosis in Connecticut, USA: Babesia lotori sp. N. The Journal of Parasitology 67: 417–425.
- Barker, R. W., A. L., Hoch, R. G. Buckner, and J. A. Hair. 1973. Hematological changes in white—tailed deer fawns, Odocoileus virginianus, infested with Theileria infected lone star ticks. The Journal of Parasitology 59: 1091–1098.
- Barnett, S. F., 1977. Theileria. In Parasitic protozoa, vol. 4. Ed. J. P. Krier. New York: Academic Press, pp. 77–113.
- Bettencourt, A., C., Franca, and J. Borges. 1907. Un cas de piroplasmose bacilliforme chez le daim. Arquivas do Instituto Bacteriologico Camara Pestana 1: 341–349.
- Birkenheuer, A. J., M., Levy, K. Savary, R. Gager, and E. Bre—itschwerdt. 1999. Babesia gibsoni infections in dogs from North Carolina. Journal of the American Animal Hospital Association 35: 125–128.
- Blouin, E. F., A. A., Kocan, K. M. Kocan, and J. A. Hair. 1984. Transmission of Cytauxzoon felis Kier, 1979 from bobcats, Felis rufus (Schreber) to domestic cats by Derma—centor variabilis (Say). Journal of Wildlife Diseases 20: 241–242.
-
Blouin, E. F.,
A. A., Kocan,
K. M. Kocan, and
J. A. Hair.
1987.
Evidence of a limited schizogenous cycle for Cytauxzoon felis in bobcats following exposure to infected ticks.
Journal of Wildlife Diseases
23:
409–501.
10.7589/0090-3558-23.3.499 Google Scholar
- Butt, M. T., D., Bowman, M. C. Barr, and M. E. Roelke. 1991. Latrogenic transmission of Cytauxzoon felis from a Florida panther (Felix concolor coryi) to a domestic cat. Journal of Wildllife Diseases 27: 342–347.
- Chae, J., S., Waghela, T. Craig, A. Kocan, G. Wagner, and P. Holman. 1999. Two Theileria cervi SSU RRNA gene sequence types found in isolates from white—tailed deer and elk in North America. Journal of wildlife Diseases 35: 458–465.
- Clark, H. C., 1918. Piroplasmosis of cattle in Panama. Journal of Infectious Diseases 22: 159–168.
- Clark, H. C., and J. Zetek. 1925. Tick biting experiments in bovine and cervine piroplasms. American Journal of Tropical Medicine 5: 17–26.
- Conrad, P. A., and K. A. Waldrup. 1993. Babesiosis and theile—riosis in free—ranging and captive artiodactylids. In Zoo and wild animal medicine. Vol. 3, Current therapy. Ed. M. E. Fowler. Philadelphia, PA: W. B. Saunders Co., pp. 506–511.
- Conrad, P. A., B. G., Kelly, and C. G. D. Brown. 1985. Intraery—throcytic schizogony of Theileria annulata. Parasitology 91: 67–82.
- Conrad, P. A., J., Thomford, I. Yamane, J. Whiting, L. Bosma, T. Uno, H. J. Holshuh, and S. Shelly. 1991. Hemolytic anemia caused by Babesia gibsoni infection in dogs. Journal of the American Veterinary Medical Association 199: 601–605.
- Cooksey, L. M., R., Davey, E. Ahrens, and J. George. 1989. Suitability of white—tailed deer as hosts for cattle fever ticks (Acari: Ixodidae). Journal of Medical Entomology 26: 155–158.
- Davey, R. B., 1993. Stagewise mortality, ovipositional biology, and egg viability of Boophilus annulatus (Acari: Ixodi—dae) on Boselaphus tragocamelus (Artiodactyla: Bovi—dae). Journal of Medical Entomology 30: 997–1002.
- Davidson, W. R., J. M., Crum, J. L. Blue, D. W. Sharp, and J. H. Phillips. 1985. Parasites, diseases and health status of sympatric populations of fallow deer and white—tailed deer in Kentucky. Journal of Wildlife Diseases 21: 153–159.
- Droleskey, R. E., P. J., Holman, K. W. Waldrup, D. E. Corrier, and G. G. Wagner. 1993. Ultrastructural characteristics of Babesia odocoilei in vitro. The Journal of Parasitology 79: 424–434.
- Emerson, H. R., 1969. A comparison of parasitic infections of white—tailed deer (Odocoileus virginianus) from central and east Texas. Bulletin of the Wildlife Disease Association 5: 137–139.
- Emerson, H. R., and W. T. Wright. 1968. Isolation of a Babesia in white—tailed deer. Bulletin of the Wildlife Disease Association 4: 142–143.
- Ewing, S. A., R., Buckner, and B. Stringer. 1964. The coyote, a potential host for Babesia canis and Ehrlichia sp. The Journal of Parasitology 50: 704.
- Fawcett, D. W., A. S., Young, and B. L. Leitch. 1985. Sporogony in Theileria (Apicomplexa: Piroplasmida). A comparative ultrastructural study. Journal of Submicroscopic Cytology 17: 299–314.
- Frerichs, W. M. and A., Holbrook. 1970. Babesia sp. and Haemobartonella sp. in wild mammals trapped at the Agricultural Research Center, Beltsville, Maryland. The Journal of Parasitology 56: 130.
- George, J. E., 1996. The campaign to keep Boophilus ticks out of the United States: Technical problems and solutions. Proceedings of the United States Animal Health Association 100: 196–206.
- Glenn, B. L., and E. L. Stair. 1984. Cytauxzoonosis in domestic cats: Report of two cases in Oklahoma with a review and discussion of the disease. Journal of the American Veterinary Medical Association 184: 822–825.
- Glenn, B. L., R. E., Rolley, and A. A. Kocan. 1982. Cytauxzoon—like piroplasms observed in erythrocytes of wild—tapped bobcats (Lynx rufus rufus) in Oklahoma. Journal of the American Veterinary Medical Association 181: 1251–1253.
- Glenn, B. L., A. A., Kocan, and E. F. Blouin. 1983. Cytaux—zoonosis in bobcats. Journal of the American Veterinary Medical Association 183: 1155–1158.
- Goff, W., D., Jessup, K. Waldrup, J. Gorham, and G. Wagner. 1993. The isolation and partial characterization of a Babesia spp. from desert bighorn sheep (Ovis canaden—sis nelsoni). Journal of Eukaryotic Microbiology 40: 237–243.
- Gray, J. H., and G. O. Schubert. 1979. Report of the Committee on parasitic diseases and parasiticides tick eradication program. Proceedings of the United States Animal Health Association 83: 347–349.
- Gray, J. S., T. M., Muphy, K. A. Waldrup, G. G. Wagner, D. A. Blewett, and R. Harrington. 1991. Comparative studies of Babesia spp. from white—tailed and sika deer. Journal of Wildlife Diseases 27 (1): 86–91.
-
Grootenhuis, J. G., and
A. S. Young.
1981.
The involvement of wildlife in Theileria infections of domestic animals in East Africa.
In Advances in the control of theileriosis.
Ed. A. D. Irvin,
M. P. Cunningham, and
A. S. Young.
Boston:
Martinus Nijhoff,
pp. 71–73.
10.1007/978-94-009-8346-5_8 Google Scholar
- Hair, J. A., and J. L. Bowman. 1986. Behavioral ecology of Amblyomma americanum (L). In Morphology. physiology, and behavioral biology of ticks. Ed. J. Sauer and J. Hair. New York: Ellis Horwood Limited, pp. 406–420.
- Hazen-Karr, C. G., A. A., Kocan, K. M. Kocan, and J. A. Hair. 1987. The ultrastructure of sporogony in Theileria cervi (Bettencourt et al., 1907) in salivary glands of female Amblyomma americanum (L.) ticks. The Journal of Par—asitology 73: 1182–1188.
- Holman, P. J., K., Waldrup, and G. Wagner. 1988. In vitro cultivation of a Babesia isolate from a white—tailed deer (Odocoileus virginianus). The Journal of Parasitology 74: 111–115.
- Holman, P. J., K. A., Waldrup, E. Droleskey, D. E. Corrier, and G. G. Wagner. 1993. In vitro growth of Babesia bovis in white—tailed deer (Odocoileus virginianus) erythrocytes. The Journal of Parasitology 79: 233–237.
- Holman, P. J., K., Petrini, J. Rhyan, and G. Wagner. 1994a. In vitro isolation and cultivation of a Babesia sp. from an American woodland caribou (Rangifer tarandus caribou). Journal of Wildlife Diseases 30: 195–200.
- Holman, P. J., T., Craig, D. Crider, K. Petrini, J. Rhyan, and G. Wagner. 1994b. Culture, isolation and partial characterization of a Babesia sp. from a North American elk (Cervus elaphus). Journal of Wildlife Diseases 30: 460–465.
- Kakoma, I., and H. Mehlhorn. 1994. Babesia in domestic animals. In Parasitic protozoa, vol. 7. Ed. J. P. Krier. New York: Academic Press, pp. 147–216.
- Kjemtrup, A. M., J. W., Thomford, I. A. Gardner, P. A. Conrad, D. A. Jessup, and W. M. Boyce. 1995. Seroprevalence of two Babesia spp. isolated in selected bighorn sheep (Ovis canadensis) and mule deer (Odocoileus hemionus) populations in California. Journal of Wildlife Diseases 31: 467–471.
- Kocan, A. A., and K. M. Kocan. 1991. Tick—transmitted diseases of wildlife in North America. Bulletin of the Society of Vector Ecology 16: 94–108.
- Kocan, A. A., E. F., Blouin, and B. L. Glenn. 1985. Hematologic and serum chemical values for free—ranging bobcats Felis rufus (Schreber), with reference to animals with natural infections of Cytauxzoon felis Kier, 1979. Journal of Wildlife Diseases 21: 190–192.
- Kocan, A. A., S. W., Mukolwe, and S. J. Laird. 1987. The inability to infect fallow deer (Cervis dama) with Theile—ria cervi. Journal of Wildlife Diseases 23: 674–676.
- Kocan, A. A., K. M., Kocan, C. Hazen-Karr, and J. A. Hair. 1988. Electron microscopic observations of Theileria cervi in salivary glands of male Amblyomma ameri—canum. Proceedings of the Helminthological Society of Washington 55: 55–57.
- Kocan, A. A., K. M., Kocan, E. F. Blouin, and S. W. Mukolwe. 1992. A redescription of schizogony of Cytauxzoon felis in the domestic cat. Annals New York Academy of Sciences 653: 161–167.
- Krier, J. P., M., Ristic, and A. M. Watrach. 1962. Theileria sp. in a deer in the United States. American Journal of Veterinary Research 23: 657–662.
- Kuttler, K., 1988. World wide impact of babesiosis. In Babesiosis of domestic animals and man. Ed. M. Ristic. Boca Raton, FL: CRC Press, pp. 1–22.
-
Kuttler, K.,
R. M., Robinson, and
R. R. Bell.
1967.
Tick transmission of theileriosis in white—tailed deer.
Bulletin of the Wildlife Disease Association
3:
182–183.
10.7589/0090-3558-3.4.182 Google Scholar
- Kuttler, K., O. H., Graham, S. R. Johnson, and J. L. Trevino. 1972. Unsuccessful attempts to establish cattle Babesia infections in white—tailed deer. Journal of Wildlife Diseases 8: 63–66.
- Laird, J. S., A. A., Kocan, K. M. Kocan, S. M. Presley, and J. A. Hair. 1988. Susceptibility of Amblyomma americanum to natural and experimental infections with Theileria cervi. Journal of Wildlife Diseases 24: 679–683.
- Levine, N. D., 1971. Taxonomy of the piroplasms. Transactions of the American Microscopic Society 90: 2–33.
- Mehlhorn, H. and E., Schein. 1984. The piroplasms: Life cycle and sexual stages. Advances in Parasitology 23: 37–102.
- Mehlhorn, H., E., Schein, and J. S. Ahmed. 1994. Theileria. In Parasitic protozoa, vol. 7. Ed. J. P. Kreier. New York: Academic Press, pp. 217–304.
- Mitema, E. S., A. A., Kocan, S. W. Mukolwe, S. Sangiah, and D. Sherban. 1991. Activity of buparvaquone against Theile—ria cervi in white—tailed deer. Veterinary Parasitology 38: 49–53.
- Motzel, S. and J. E., Wagner. 1990. Treatment of experimentally induced cytauxzoonosis in cats with parvaquone and buparvaquone. Veterinary Parasitology 35: 131–138.
- Mutugi, J. J., A. S., Young, A. C. Maritim, S. G. Ndungu, D. A. Stagg, J. G. Grootenhuis, and B. L. Leitch. 1988a. Immunization of cattle against theileriosis using varying dosages of Theileria parva lawrencei and T. Parva parva sporozoites and oxytetracycline treatments. International Journal of Parasitology 18 (4): 453–461.
- Mutugi, J. J., A. S., Young, A. C. Maritim, A. Linyoni, S. K. Mbogo, and B. L. Leitch. 1988b. Immunization of cattle using varying infective dosages of Theileria parva lawrencei sporozoites derived from an African buffalo (Syncerus caffer) and treatment with buparvaquone. Pa r —asitology 96: 391–402.
- Neitz, W. O., and A. D. Thomas. 1948. Cytauxzoon sylvicaprae gen. nov., spec. nov., a piroplasm responsible for the hitherto undescribed disease of the duiker (Sylvicaprae grim—mia). Onderstepoort Journal of Veterinary Science and Animal Industry 23: 63–76.
- Park, R. L., O., Skov, G. A. Seaman, and R. M. Bondl. 1966. Deer and cattle fever ticks. The Journal of Wildlife Management 30: 202–203.
- Perry, B. D., D. K., Nickols, and E. S. Cullom. 1985. Babesia odocoilei Emerson and Wright, 1970, in white—tailed deer, Odocoileus virginianus, in Virginia. Journal of Wildlife Diseases 21: 149–152.
- Persing, D. A., and P. C. Conrad. 1995. Babesiosis: New insight from phylogenetic analysis. Infectious Agents and Disease 4: 182–195.
- Persing, D. A., B., Herwaldt, C. Glaser, R. Lane, J. Thomford, D. Mathiesen, P. Krause, D. Phillip, and P. Conrad. 1995. Infection with a Babesia– like organism in Northern California. The New England Journal of Medicine 332: 298–303.
- Petrini, K. R., P. J., Holman, J. C. Rhyan, S. J. Jenkins, and G. G. Wagner. 1995. Fatal babesiosis in an American woodland caribou (Rangifer tarandus caribou). Journal of Zoo and Wildlife Medicine 26 (2): 298–305.
- Potgieter, F. T., and H. J. Els. 1974. An electron microscopic study of intra—erythrocytic stage of Babesia bovis in the brain capillaries of infected splenectomized calves. Onderstepoort Journal of Veterinary Research 46: 41–49.
- Purnell, R. E., 1981. Babesiosis in various hosts. In Babesiosis. Ed. M. Ristic and J. P. Krier. New York: Academic Press, pp. 25–63.
- Purnell, R. E., D., Lewis, M. R. Holman, and E. R. Young. 1981. Investigations on a Babesia isolated from Scottish sheep. Parasitology 83: 347–356.
- Ristic, M., and G. E. Lewis. 1977. Babesia in man and wild and laboratory—adapted mammals. In Parasitic protozoa, vol. 4. Ed. J. P. Krier. New York: Academic Press, pp. 53–76.
- Robinson, R. M., K. L., Kuttler, J. W. Thomas, and R. G. Mar—burger. 1967. Theileriosis in Texas white—tailed deer. The Journal of Wildlife Management 31: 455–549.
- Robinson, R. M., K. L., Kuttler, H. R. Emerson, L. P. Jones, and R. G. Marburger. 1968. Blood parasites in Texas deer. Transactions 33rd North American Wildlife Natural Resource Conference 33: 359–364.
- Roher, D. P., J. F., Anderson, and S. W. Nielson. 1985. Experimental babesiosis in coyotes and coydogs. American Journal of Veterinary Research 46: 256–262.
- Rostein, D. S., S., Taylor, J. Harvey, and J. Bean. 1999. Hema—tologic effects of cytauxzoonosis in Florida panthers and Texas cougars in Florida. Journal of Wildlife Diseases 35: 613–617.
- Schaffer, G. D., W., Hanson, W. Davidson, and V. Nettles. 1978. Haematotropic parasites of translocated raccoons in the southeast. Journal of the American Veterinary Medical Association 173: 1148–1151.
- Schein, E., H., Mehlhorn, and M. Warnecke. 1978. Electron microscopic studies of the schizogony of four Theileria species of cattle (T. parva, T. lawrenci, T. annulata, and T. mutans). Parasitologica 14: 337–348.
- Simpson, C. F., J. W., Harvey, M. J. Lawman, J. Murray, A. A. Kocan, and J. C. Carlisle. 1985. Ultrastructure of schizonts in the liver of cats with experimentally induced cytauxzoonosis. American Journal of Veterinary Research 46: 384–390.
- Spielman, A., P., Etkind, J. Piesman, T. Ruebush, D. Jaranek, and M. Jacobs. 1981. Reservoir hosts of human babesio—sis on Nantucket Island. American Journal of Tropical Medicine and Hygiene 30: 560–565.
- Spindler, L. A., R. W., Allen, L. S. Diamond, and J. C. Lotz. 1958. Babesia in white—tailed deer. Journal of Protozoology 5: 8.
- Splitter, E. J., 1950. Theileria mutans associated with bovine anaplasmosis in the United States. Journal of the American Medical Association 117: 134–135.
- Starcovici, C., 1893. Bemerkungen uber den durch Babes ent—deckten Blutparasiten und die durch denselben hervoüge—brachten Krankheiten, die seuchenhafte Hämoglobinurie des Rinds (Babes), des Texasfieber (Th. Smith), und der Carceag der Schafe (Babes). Zentralblatt für Bakteriolo—gie, Parasitenkunde, Infektionskrankheiten und Hygiene, Abteilung I: Medizinisch—Hygienische Bakteriologie, Virusforschung und Parasitologie, Originale 14: 1–8.
- Telford, S., and D. J. Forrester. 1991. Haemoparasites of raccoons (Procyon lotor) in Florida. Journal of Wildlife Diseases 27: 486–490.
-
Telford, S.,
A., Gorenflot,
P. Brasseur, and
A. Spielman.
1993.
Babesial infections in humans and wildlife.
In Parasitic protozoa,
vol. 5.
New York:
Academic Press,
pp. 1–27.
10.1016/B978-0-12-426015-3.50006-6 Google Scholar
- Thomford, J. W., P. A., Conrad, S. R. Thelford, D. Mathiesen, B. H. Bowman, A. Spielman, M. L. Eberhard, B. L. Her—waldt, R. E. Quick, and D. H. Persing. 1994. Cultivation and phylogenetic characterization of a newly recognized human pathogenic protozoan. Journal of Infectious Diseases 169: 1050–1056.
- Uilenberg, G., F. F., Franssen, and N. M. Perie. 1987. Relationships between Cytauxzoon felis and African piroplasms. Veterinary Parasitology 26: 21–28.
- Wagner, J. E., 1976. A fatal cytauxzoonosis—like disease in domestic cats. Journal of the American Veterinary Medical Association 168: 585–588.
- Waldrup, K., A. E., Collisson, S. E. Bentsen, C. K. Winkler, and G. G. Wagner. 1989a. Prevalence of erythrocytic protozoa and serologic reactivity to selected pathogens in deer in Texas. Preventative Veterinary Medicine 7: 49–58.
- Waldrup, K., A. A., Kocan, T. Quereshi, D. S. Davis, D. Baggett, and G. G. Wagner. 1989b. Serologic prevalence and isolation of Babesia odocoilei among white—tailed deer (Odocoileus virginianus) in Texas and Oklahoma. Journal of Wildlife Diseases 25: 194–201.
- Waldrup, K., A. A. Kocan, R. W. Barker, and G. G. Wagner. 1990. Transmission of Babesia odocoilei in white—tailed deer (Odocoileus virginianus) by Ixodes scapularis (Acari: Ixo—didae). Journal of Wildlife Diseases 26: 390–391.
- Waldrup, K. A., J., Moritz, D. Baggett, S. Magyar, and G. G. Wagner. 1992. Monthly incidence of Theileria cervi and seroconversion to Babesia odocoilei in white—tailed deer (Odocoileus virginianus) in Texas. Journal of Wildlife Diseases 28 (3): 457–459.
- Whiteman, S. R., A. B., Kier, and J. E. Wagner. 1977. Clinical features of feline cytauxzoonosis, a newly described blood parasitic disease. Feline Practice 7: 23–26.
- Willadsen, P., and F. Jongejan. 1999. Immunology of the tick—host interaction and the control of ticks and tick—borne diseases. Parasitology Today 15: 258–262.
- Woods, S. F., 1952. Mammal blood parasite records from the southwestern United States and Mexico. The Journal of Parasitology 38: 85–86.
- Yamane, I., I., Gardner, C. Ryan, M. Levy, J. Urrico, and P. A. Conrad. 1994. Serosurvey of Babesia canis, Babesia gib—soni, and Ehrlichia canis in pound dogs in California, USA. Preventative Veterinary Medicine 18: 293–304.
- Young, A. S., B. L., Leitch, R. M. Newson, and M. P. Cunningham. 1986. Maintenance of Theileria parva parva infection in an endemic area of Kenya. Parasitology 93: 9–16.
- Zaugg, J. L., and K. Kuttler. 1987. Experimental infections of Babesia bigemina in American bison. Journal of Wildlife Diseases 23: 99–102.
- Zinkl J. G., S. W. McDonald, A. B. Keir, and S. S. Cippa. 1981. Cytauxzoon– like organisms in erythrocytes of two cheetahs. Journal of the American Veterinary Medical Association 179: 1261–1262.