RAPID REVIEW

Donor iron depletion: beneficial or burdensome?

Corresponding Author

Ralph R. Vassallo MD

[email protected]

Vitalant, Scottsdale, Arizona

Address reprint requests to: Ralph R. Vassallo, MD, FACP, Vitalant, 6210 East Oak Street, Scottsdale, AZ 85257; e-mail: [email protected]Search for more papers by this author

Ralph R. Vassallo MD,

Corresponding Author

Ralph R. Vassallo MD

[email protected]

Vitalant, Scottsdale, Arizona

Address reprint requests to: Ralph R. Vassallo, MD, FACP, Vitalant, 6210 East Oak Street, Scottsdale, AZ 85257; e-mail: [email protected]Search for more papers by this author

First published: 29 March 2019

https://doi.org/10.1111/trf.15282

Citations: 7

Correction added on 03rd April 2019, after first online publication: Conflict of interest statement updated.

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KEY IDEAS

Most purported benefits of blood donation have not been proven. While studies suggest individuals with type II diabetes have transiently improved postdonation glycemic control, the mechanism is unknown.
Blood donors with nonanemic or mildly anemic iron deficiency can develop pica and undergo unnecessary diagnostic procedures. Lower infant birth weight has been documented in female blood donors. In other healthy populations, reversible fatigue and exercise capacity impairment occur with mild iron deficiency. The effects of donor iron depletion on cognition and neurocognitive outcomes after pregnancy continue to be studied.
Blood collectors are beginning to implement enhanced educational and interventional measures to prevent iron depletion in at-risk donors.

CONFLICT OF INTEREST

Author has disclosed Scientific Advisory Board membership with HemaStrat.

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Volume59, Issue7

July 2019

Pages 2184-2186

Donor iron depletion: beneficial or burdensome?

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Donor iron depletion: beneficial or burdensome?

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