Volume 54, Issue 6 pp. 1630-1633

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Severe pertussis and hyperleukocytosis: is it time to change for exchange?

Amir Kuperman,

Amir Kuperman

Pediatric Hematology Clinic and Coagulation Service, Western Galilee Hospital, Naharia, Israel

Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel

These authors contributed equally.Search for more papers by this author

Yoav Hoffmann,

Corresponding Author

Yoav Hoffmann

Pediatric Intensive Care Unit, Western Galilee Hospital, Naharia, Israel

These authors contributed equally.Address reprint requests to: Yoav Hoffmann, MD, The Pediatric Intensive Care Unit, Western Gallile Hospital, Naharia 22100, Israel; e-mail: [email protected].Search for more papers by this author

Danny Glikman,

Danny Glikman

Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel

Infectious Disease Unit, Western Galilee Hospital, Naharia, Israel

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Husein Dabbah,

Husein Dabbah

Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel

Pediatric Pulmonology Clinic, Western Galilee Hospital, Naharia, Israel

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Zeev Zonis,

Zeev Zonis

Pediatric Intensive Care Unit, Western Galilee Hospital, Naharia, Israel

Search for more papers by this author

Amir Kuperman,

Amir Kuperman

Pediatric Hematology Clinic and Coagulation Service, Western Galilee Hospital, Naharia, Israel

Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel

These authors contributed equally.Search for more papers by this author

Yoav Hoffmann,

Corresponding Author

Yoav Hoffmann

Pediatric Intensive Care Unit, Western Galilee Hospital, Naharia, Israel

Danny Glikman,

Danny Glikman

Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel

Infectious Disease Unit, Western Galilee Hospital, Naharia, Israel

Search for more papers by this author

Husein Dabbah,

Husein Dabbah

Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel

Pediatric Pulmonology Clinic, Western Galilee Hospital, Naharia, Israel

Search for more papers by this author

Zeev Zonis,

Zeev Zonis

Pediatric Intensive Care Unit, Western Galilee Hospital, Naharia, Israel

Search for more papers by this author

First published: 16 December 2013

https://doi.org/10.1111/trf.12519

Citations: 26

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Abstract

Background

Pertussis is an important cause of infant death worldwide and continues to be a public health concern even in countries with high vaccination coverage. Severe (critical) pertussis with hyperleukocytosis is a severe form of the disease with up to 80% mortality rate. Attempts have been reported to reduce the white blood cell burden by exchange transfusion (ET) with conflicting conclusions.

Case Report

We report a case of critical pertussis in a neonate who was treated with ET, in view of a comprehensive literature review.

Results

The patient was discharged without any sequelae.

Conclusion

ET should be considered in all infants suffering from critical pertussis and hyperleukocytosis, even in secondary care community hospitals.

References

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Volume54, Issue6

June 2014

Pages 1630-1633

Severe pertussis and hyperleukocytosis: is it time to change for exchange?

Abstract

Background

Case Report

Results

Conclusion

References

Citing Literature

References

Information

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Severe pertussis and hyperleukocytosis: is it time to change for exchange?

Abstract

Background

Case Report

Results

Conclusion

References

Citing Literature

References

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