Unplanned implant removal in locally advanced breast cancer
Corresponding Author
Justin D. Anderson MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Correspondence
Justin D. Anderson, Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA.
Email: [email protected]
Search for more papers by this authorJacob B. Hammond MD
Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorHeidi E. Kosiorek MS
Department of Health Sciences Research, Division of Biostatistics, Mayo Clinic, Scottsdale, AZ, USA
Search for more papers by this authorCameron S. Thorpe MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorRonik S. Bhangoo MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorBarbara A. Pockaj MD
Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorRichard J. Gray MD
Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorPatricia A. Cronin MD
Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorAlanna M. Rebecca MD
Department of Plastic Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorWilliam J. Casey MD
Department of Plastic Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorWilliam W. Wong MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorSameer R. Keole MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorTamara Z. Vern-Gross MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorLisa A. McGee MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorMichele Y. Halyard MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorTodd A. DeWees PhD
Department of Health Sciences Research, Division of Biostatistics, Mayo Clinic, Scottsdale, AZ, USA
Search for more papers by this authorCarlos E. Vargas MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorCorresponding Author
Justin D. Anderson MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Correspondence
Justin D. Anderson, Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA.
Email: [email protected]
Search for more papers by this authorJacob B. Hammond MD
Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorHeidi E. Kosiorek MS
Department of Health Sciences Research, Division of Biostatistics, Mayo Clinic, Scottsdale, AZ, USA
Search for more papers by this authorCameron S. Thorpe MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorRonik S. Bhangoo MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorBarbara A. Pockaj MD
Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorRichard J. Gray MD
Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorPatricia A. Cronin MD
Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorAlanna M. Rebecca MD
Department of Plastic Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorWilliam J. Casey MD
Department of Plastic Surgery, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorWilliam W. Wong MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorSameer R. Keole MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorTamara Z. Vern-Gross MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorLisa A. McGee MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorMichele Y. Halyard MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorTodd A. DeWees PhD
Department of Health Sciences Research, Division of Biostatistics, Mayo Clinic, Scottsdale, AZ, USA
Search for more papers by this authorCarlos E. Vargas MD
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA
Search for more papers by this authorAbstract
Study conducted to determine frequency and timing of unplanned breast implant removal after mastectomy, reconstruction, and postmastectomy radiation (PMRT). From 2010–2017, 52 patients underwent mastectomy, reconstruction, and PMRT. With median follow-up of 3.1 years, 23 patients (44%) experienced implant removal. Implant removal occurred in 9 (17%) patients before starting PMRT and 14 (27%) patients after starting PMRT. Implant removal rates were similar for hypofractionated PMRT compared with standard fractionation and for proton compared with photon PMRT. Implant removal is common for women undergoing mastectomy and reconstruction followed by PMRT. The risk is clinically significant even before starting radiation.
CONFLICT OF INTEREST
The authors have no conflicts of interest to disclose in the publication of this manuscript.
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