The ICD-11 compatible, Personality Inventory for DSM-5–Brief Form Plus, Modified (PID5BF+M), has recently been developed to assess the constructs of the ICD-11 and DSM-5 maladaptive trait models. This meta-analysis aimed to evaluate the pooled estimates of the structural validity (model fit indices, factor loadings, and internal consistency of individual scales), discriminant validity (factor intercorrelations), and criterion validity (standardized mean differences between clinical and nonclinical samples) of the PID5BF+M. A systematic search for scientific articles published between January 2013 and November 2024 was conducted in PubMed, PsycNET, and Google Scholar. The pooled estimates were calculated using the random effects method following the PRISMA guidelines. The quality of individual studies, heterogeneity, and publication bias were checked. Five high-quality reports including 21 independent samples (3056 patients and 17,361 nonpatients) were entered into the meta-analysis. The six-factor structure of the PID5BF+M was supported by the pooled estimates of model fit (RMSEA = 0.03, CFI = 0.98, TLI = 0.96, and SRMR = 0.01), moderate to very strong factor loadings (from 0.43 to 0.74), and an acceptable internal consistency (ω between 0.70 and 0.79 for all factors with a median of 0.75). The factor intercorrelations were weak to moderate (from 0.05 to 0.38) and the mean scores of most factors (except antagonism) were higher in the patients. The PID5BF+M is an applicable scale to measure maladaptive personality constructs with acceptable structural, discriminant, and criterion validity. Mental health professionals and researchers can use the scale, taking into account some methodological considerations of the present meta-analysis. The study protocol was preregistered in PROSPERO-CRD42024507164.