Volume 26, Issue 8 e14392
ORIGINAL ARTICLE

Clinical approach to vasoplegia in the transplant patient from the Pediatric Heart Transplant Society

Shriprasad R. Deshpande

Shriprasad R. Deshpande

Department of Cardiology and Cardiovascular Surgery, Children's National Hospital, The George Washington University, Washington, DC, USA

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David W. Bearl

David W. Bearl

Department of Pediatric Cardiology, Monroe Carell Jr. Children's Hospital, Nashville, Tennessee, USA

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Pirooz Eghtesady

Pirooz Eghtesady

Section of Pediatric Cardiothoracic Surgery, St Louis Children's Hospital and School of Medicine, Washington University, St Louis, Michigan, USA

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Heather T. Henderson

Heather T. Henderson

Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA

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Scott Auerbach

Scott Auerbach

Pediatrics, Division of Cardiology, University of Colorado, Denver Anschutz Medical Campus, Children's Hospital Colorado Aurora, Aurora, Colorado, USA

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Aamir Jeewa

Aamir Jeewa

Department of Cardiology, Hospital for Sick Children, Toronto, Ontario, Canada

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Neha Bansal

Neha Bansal

Children's Hospital at Montefiore, Bronx, New York, USA

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Shahnawaz Amdani

Shahnawaz Amdani

Cleveland Clinic Children's, Cleveland, Ohio, USA

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Marc E. Richmond

Marc E. Richmond

Division of Pediatric Cardiology, Department of Pediatrics, Columbia University College of Physician and Surgeons, Morgan Stanley Children's Hospital, New York, New York, USA

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Loren D. Sacks

Loren D. Sacks

Pediatric Cardiology, Stanford University School of Medicine, Palo Alto, California, USA

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Renata Shih

Renata Shih

Congenital Heart Center, Division of Pediatric Cardiology, University of Florida, Gainesville, Florida, USA

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Madeleine Townsend

Madeleine Townsend

Cleveland Clinic Children's, Cleveland, Ohio, USA

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Jennifer Conway

Corresponding Author

Jennifer Conway

Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada

Correspondence

Jennifer Conway, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada.

Email: [email protected]

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First published: 14 November 2022
Citations: 2

Abstract

This manuscript outlines a clinical approach to vasoplegia incorporating the current state of knowledge regarding vasoplegia in pediatric patients immediately post-transplant and to identify modifiable factors both pre- and post-transplant that may reduce post-operative morbidity, end-organ dysfunction, and mortality. Centers participating in the Pediatric Heart Transplant Society (PHTS) were asked to provide their internal protocols and rationale for vasoplegia management, and applicable adult and pediatric data were reviewed. The authors synthesized the above protocols and literature into the following description of clinical approaches to vasoplegia highlighting areas of both broad consensus and of significant practice variation.

CONFLICT OF INTEREST

All authors have no relevant conflicts of interest.

DATA AVAILABILITY STATEMENT

Data for the manuscript can be found in the sited peer-reviewed articles.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.