Collaborative Brazilian pediatric renal transplant registry (CoBrazPed-RTx): A report from 2004 to 2018
Corresponding Author
Vandrea Carla de Souza
Programa de Pós-graduação em Ciências da Saúde, Universidade de Caxias do Sul/Hospital Geral de Caxias do Sul, Caxias do Sul, Brazil
Correspondence
Vandrea Carla de Souza, Programa de Pós-graduação em Ciências da Saúde, Universidade de Caxias do Sul/Hospital Geral de Caxias do Sul, Rua Adelino Roldo, 310 – Caxias do Sul- Brazil - 95052-020.
Email: [email protected]
Search for more papers by this authorClotilde Druck Garcia
Department of Nephrology, Organ Donation and Transplantation Program, Universidade Federal Ciencias da Saude de Porto Alegre, Porto Alegre, Brazil
Search for more papers by this authorJose Medina Pestana
Hospital do Rim. Universidade Federal de São Paulo, são Paulo, Brazil
Search for more papers by this authorSuelen Bianca Stopa Martins
Hospital do Rim. Universidade Federal de São Paulo, são Paulo, Brazil
Search for more papers by this authorLuciana de Fátima Porini Custódio
Hospital do Rim. Universidade Federal de São Paulo, são Paulo, Brazil
Search for more papers by this authorViviane Bittencourt
Hospital da Criança Santo Antônio-Santa Casa, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil
Search for more papers by this authorRoberta Rohde
Hospital da Criança Santo Antônio-Santa Casa, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil
Search for more papers by this authorIzadora Simões Pires
Hospital da Criança Santo Antônio-Santa Casa, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil
Search for more papers by this authorMaria Fernanda de Camargo
Hospital Samaritano, São Paulo, São Paulo, Brazil
Search for more papers by this authorPaulo Koch Nogueira
Hospital Samaritano, São Paulo, São Paulo, Brazil
Search for more papers by this authorLuciana de Santis Feltran
Hospital Samaritano, São Paulo, São Paulo, Brazil
Search for more papers by this authorRonaldo de Matos Esmeraldo
Hospital Geral de Fortaleza, Fortaleza, Brazil
Search for more papers by this authorRebeca Carvalho Souza Costa
Hospital Geral de Fortaleza, Fortaleza, Brazil
Search for more papers by this authorBenita Schvartsman
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina -Universidade de São Paulo, São Paulo, Brazil
Search for more papers by this authorAndreia Watanabe
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina -Universidade de São Paulo, São Paulo, Brazil
Search for more papers by this authorMariana Faucz Munhoz da Cunha
Hospital Pequeno Príncipe, Curitiba, Curitiba, Brazil
Search for more papers by this authorRomilda Santos
Hospital Pequeno Príncipe, Curitiba, Curitiba, Brazil
Search for more papers by this authorLiliane Cury Prates
Universidade Estadual de Campinas, Campinas, Brazil
Search for more papers by this authorVera Maria Santoro Belangero
Universidade Estadual de Campinas, Campinas, Brazil
Search for more papers by this authorLilian Palma
Universidade Estadual de Campinas, Campinas, Brazil
Search for more papers by this authorHenrique Mochida Takase
Hospital das Clínicas, Faculdade de Medicina de Botucatu – UNESP, Botucatu, Brazil
Search for more papers by this authorLuiz Gustavo Mondelli de Andrade
Hospital das Clínicas, Faculdade de Medicina de Botucatu – UNESP, Botucatu, Brazil
Search for more papers by this authorSimone Paiva Laranjo Martins
Santa Casa de São Paulo, São Paulo, Brazil
Search for more papers by this authorMario Abbud-Filho
Hospital de Base, São José do Rio Preto, Brazil
Instituto Urologia e Nefrologia, São José Do Rio Preto, Brazil
Search for more papers by this authorIda Fernandes-Charpiot
Hospital de Base, São José do Rio Preto, Brazil
Search for more papers by this authorHoracio Ramalho
Hospital de Base, São José do Rio Preto, Brazil
Instituto Urologia e Nefrologia, São José Do Rio Preto, Brazil
Search for more papers by this authorAna Carmen Quaresma Mendonça
Hospital das Clínicas - UFMG, Belo Horizonte, Brazil
Search for more papers by this authorMariana Affonso Vasconcelos
Hospital das Clínicas - UFMG, Belo Horizonte, Brazil
Search for more papers by this authorMariana Guimaraes Penido de Paula
Santa Casa de Belo Horizonte, Belo Horizonte, Brazil
Search for more papers by this authorCarolina Moura Diniz Ferreira Leite
Santa Casa de Belo Horizonte, Belo Horizonte, Brazil
Search for more papers by this authorEnzo Ricardo Russo
Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto – USP, Ribeirao Preto, Brazil
Search for more papers by this authorInalda Facincani
Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto – USP, Ribeirao Preto, Brazil
Search for more papers by this authorMario Bernardes Wagner
Programa de Pós-Graduação em Saúde da Criança e do Adolescente- Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Search for more papers by this authorCorresponding Author
Vandrea Carla de Souza
Programa de Pós-graduação em Ciências da Saúde, Universidade de Caxias do Sul/Hospital Geral de Caxias do Sul, Caxias do Sul, Brazil
Correspondence
Vandrea Carla de Souza, Programa de Pós-graduação em Ciências da Saúde, Universidade de Caxias do Sul/Hospital Geral de Caxias do Sul, Rua Adelino Roldo, 310 – Caxias do Sul- Brazil - 95052-020.
Email: [email protected]
Search for more papers by this authorClotilde Druck Garcia
Department of Nephrology, Organ Donation and Transplantation Program, Universidade Federal Ciencias da Saude de Porto Alegre, Porto Alegre, Brazil
Search for more papers by this authorJose Medina Pestana
Hospital do Rim. Universidade Federal de São Paulo, são Paulo, Brazil
Search for more papers by this authorSuelen Bianca Stopa Martins
Hospital do Rim. Universidade Federal de São Paulo, são Paulo, Brazil
Search for more papers by this authorLuciana de Fátima Porini Custódio
Hospital do Rim. Universidade Federal de São Paulo, são Paulo, Brazil
Search for more papers by this authorViviane Bittencourt
Hospital da Criança Santo Antônio-Santa Casa, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil
Search for more papers by this authorRoberta Rohde
Hospital da Criança Santo Antônio-Santa Casa, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil
Search for more papers by this authorIzadora Simões Pires
Hospital da Criança Santo Antônio-Santa Casa, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil
Search for more papers by this authorMaria Fernanda de Camargo
Hospital Samaritano, São Paulo, São Paulo, Brazil
Search for more papers by this authorPaulo Koch Nogueira
Hospital Samaritano, São Paulo, São Paulo, Brazil
Search for more papers by this authorLuciana de Santis Feltran
Hospital Samaritano, São Paulo, São Paulo, Brazil
Search for more papers by this authorRonaldo de Matos Esmeraldo
Hospital Geral de Fortaleza, Fortaleza, Brazil
Search for more papers by this authorRebeca Carvalho Souza Costa
Hospital Geral de Fortaleza, Fortaleza, Brazil
Search for more papers by this authorBenita Schvartsman
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina -Universidade de São Paulo, São Paulo, Brazil
Search for more papers by this authorAndreia Watanabe
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina -Universidade de São Paulo, São Paulo, Brazil
Search for more papers by this authorMariana Faucz Munhoz da Cunha
Hospital Pequeno Príncipe, Curitiba, Curitiba, Brazil
Search for more papers by this authorRomilda Santos
Hospital Pequeno Príncipe, Curitiba, Curitiba, Brazil
Search for more papers by this authorLiliane Cury Prates
Universidade Estadual de Campinas, Campinas, Brazil
Search for more papers by this authorVera Maria Santoro Belangero
Universidade Estadual de Campinas, Campinas, Brazil
Search for more papers by this authorLilian Palma
Universidade Estadual de Campinas, Campinas, Brazil
Search for more papers by this authorHenrique Mochida Takase
Hospital das Clínicas, Faculdade de Medicina de Botucatu – UNESP, Botucatu, Brazil
Search for more papers by this authorLuiz Gustavo Mondelli de Andrade
Hospital das Clínicas, Faculdade de Medicina de Botucatu – UNESP, Botucatu, Brazil
Search for more papers by this authorSimone Paiva Laranjo Martins
Santa Casa de São Paulo, São Paulo, Brazil
Search for more papers by this authorMario Abbud-Filho
Hospital de Base, São José do Rio Preto, Brazil
Instituto Urologia e Nefrologia, São José Do Rio Preto, Brazil
Search for more papers by this authorIda Fernandes-Charpiot
Hospital de Base, São José do Rio Preto, Brazil
Search for more papers by this authorHoracio Ramalho
Hospital de Base, São José do Rio Preto, Brazil
Instituto Urologia e Nefrologia, São José Do Rio Preto, Brazil
Search for more papers by this authorAna Carmen Quaresma Mendonça
Hospital das Clínicas - UFMG, Belo Horizonte, Brazil
Search for more papers by this authorMariana Affonso Vasconcelos
Hospital das Clínicas - UFMG, Belo Horizonte, Brazil
Search for more papers by this authorMariana Guimaraes Penido de Paula
Santa Casa de Belo Horizonte, Belo Horizonte, Brazil
Search for more papers by this authorCarolina Moura Diniz Ferreira Leite
Santa Casa de Belo Horizonte, Belo Horizonte, Brazil
Search for more papers by this authorEnzo Ricardo Russo
Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto – USP, Ribeirao Preto, Brazil
Search for more papers by this authorInalda Facincani
Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto – USP, Ribeirao Preto, Brazil
Search for more papers by this authorMario Bernardes Wagner
Programa de Pós-Graduação em Saúde da Criança e do Adolescente- Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Search for more papers by this authorAbstract
The Brazilian collaborative registry for pediatric renal transplantation began in 2004 as a multicenter initiative aimed at analyzing, reporting, and disseminating the results of pediatric renal transplantation in Brazil. Data from all pediatric renal transplants performed from January 2004 to May 2018 at the 13 participating centers were analyzed. A total of 2744 pediatric renal transplants were performed in the thirteen participating centers. The median age at transplantation was 12.2 years, with the majority being male recipients (56%). The main underlying diseases were CAKUT (40.5%) and glomerulopathy (28%). 1981 (72%) of the grafts were from deceased donors (DD). Graft survival at one year (censored by death) was 94% in the live donor group (LD) and 91% in the DD group (log-rank test P < 0.01). The patient’s survival at one and 5 years was 97% and 95% for the LD group and 96% and 93% for the DD group (log-rank test P = 0.02). The graft loss rate was 19% (n = 517), more frequently caused by vascular thrombosis (n = 102) and chronic graft nephropathy (n = 90). DD recipients had 1.6 (1.0-2.2) times greater chance of death and 1.5 (1.2-1.8) times greater chance of graft loss compared to LD recipients. The mortality rate was 5.4% (n = 148), mainly due to infection (n = 69) and cardiovascular disease (n = 28). The results of this collaborative pediatric renal transplant record are comparable to other international registries, although we still have a high infection rate as a cause of death.
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