Clinical Notes
Hypofibrinogenemia and intra-articular hemorrhage due to valproic acid
Burcu Karakayalı,
Burcu Karakayalı
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Search for more papers by this author Duygu Onsal Ozturk,
Duygu Onsal Ozturk
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Search for more papers by this author Ahmet Sami Yazar,
Ahmet Sami Yazar
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Search for more papers by this author Sirin Guven,
Sirin Guven
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Search for more papers by this author Ismail Islek,
Corresponding Author
Ismail Islek
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Correspondence: Ismail Islek, MD, Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul 34760, Turkey. Email:
[email protected]Search for more papers by this author
Burcu Karakayalı,
Burcu Karakayalı
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Search for more papers by this author Duygu Onsal Ozturk,
Duygu Onsal Ozturk
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Search for more papers by this author Ahmet Sami Yazar,
Ahmet Sami Yazar
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Search for more papers by this author Sirin Guven,
Sirin Guven
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Search for more papers by this author Ismail Islek,
Corresponding Author
Ismail Islek
Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, Turkey
Correspondence: Ismail Islek, MD, Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul 34760, Turkey. Email:
[email protected]Search for more papers by this author
First published: 23 December 2016
No abstract is available for this article.
References
- 1Guerrini R. Valproate as a mainstay of therapy for pediatric epilepsy. Paediatr. Drugs 2006; 8: 113–29.
- 2Köse G, Arhan E, Unal B, Ozaydin E, Guven A, Sayli TR. Valproate-associated coagulopathies in children during short-term treatment. J. Child Neurol. 2009; 24: 1493–8.
- 3Koenig S, Gerstner T, Keller A, Teich M, Longin E, Dempfle CE. High incidence of valproate-induced coagulation disorders in children receiving valproic acid: a prospective study. Blood Coagul. Fibrinolysis 2008; 19: 375–82.
- 4Serdaroglu G, Tütüncüoglu S, Kavakli K, Tekgül H. Coagulation abnormalities and acquired von Willebrand's disease type 1 in children receiving valproic acid. J. Child Neurol. 2002; 17: 41–3.
- 5Chen HF, Xu LP, Luo ZY et al. Valproic acid-associated low fibrinogen and delayed intracranial hemorrhage: case report and mini literature review. Drug Des. Devel. Ther. 2013; 7: 767–70.
