Volume 25, Issue 5 pp. 832-835
Case Report

Manganese Encephalopathy among Ephedron Abusers-Case Reports

Justyna Janocha-Litwin MD

Corresponding Author

Justyna Janocha-Litwin MD

First Department of Infectious Disease, J. Gromkowski Specialist Regional Hospital in Wroclaw, Wroclaw, Poland

Correspondence: Address correspondence to Justyna Janocha-Litwin, First Department of Infectious Disease, J. Gromkowski Specialist Regional Hospital in Wroclaw, Koszarowa 5, Wroclaw 51–149, Poland. E-mail: [email protected].Search for more papers by this author
Katarzyna Marianska PhD

Katarzyna Marianska PhD

Department of Neurology, J. Gromkowski Specialist Regional Hospital in Wroclaw, Wroclaw, Poland

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Sylwia Serafinska PhD

Sylwia Serafinska PhD

First Department of Infectious Disease, J. Gromkowski Specialist Regional Hospital in Wroclaw, Wroclaw, Poland

Faculty of Medicine and Dentistry of the Wroclaw Medical University, Department of Infectious Diseases and Hepatology, Wroclaw, Poland

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Krzysztof Simon MD, PhD

Krzysztof Simon MD, PhD

First Department of Infectious Disease, J. Gromkowski Specialist Regional Hospital in Wroclaw, Wroclaw, Poland

Faculty of Medicine and Dentistry of the Wroclaw Medical University, Department of Infectious Diseases and Hepatology, Wroclaw, Poland

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First published: 26 September 2014
Citations: 13

Conflict of Interest: None.

Disclosure: The authors report no conflict of interest.

ABSTRACT

Ephedrone encephalopathy is referred to as a group of symptoms of manganese deposition within the central nervous system (CNS), resulting from the abuse of ephedrone (methcathinone), obtained in reaction using the excess amount of manganese-containing oxidants. The diagnosis is based on the contrast-enhanced head MRI findings characteristic for this syndrome, clinical manifestation and history of ephedrone use. The syndrome has been reported in recent years in young people from Eastern Europe and Russia with a history of ephedrone overuse. However, no report has ever been published on ephedrone encephalopathy in Polish patients.

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