Volume 43, Issue 1 pp. 22-30
Original Article

Continuous infusion of propofol or intermittent bolus of tiletamine-zolazepam in feline night monkeys (Aotus infulatus)

Rafaela Galante

Rafaela Galante

Veterinary Anesthesia and Analgesia Laboratory, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Brazil

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José A.P.C. Muniz

José A.P.C. Muniz

National Primate Center, Evandro Chagas Institute, Ministry of Health, Ananindeua, Brazil

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Paulo H.G. Castro

Paulo H.G. Castro

National Primate Center, Evandro Chagas Institute, Ministry of Health, Ananindeua, Brazil

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Dorli S. Amora Jr

Dorli S. Amora Jr

Veterinary Anesthesia and Analgesia Laboratory, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Brazil

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Vanessa N. Gris

Vanessa N. Gris

Veterinary Anesthesia and Analgesia Laboratory, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Brazil

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Elizabeth R. Carvalho

Elizabeth R. Carvalho

Veterinary Anesthesia and Analgesia Laboratory, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Brazil

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Ricardo G.D′O.C. Vilani

Corresponding Author

Ricardo G.D′O.C. Vilani

Veterinary Anesthesia and Analgesia Laboratory, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Brazil

Correspondence

Ricardo G.D′O.C. Vilani, Departamento de Medicina Veterinária, Universidade Federal do Paraná, Rua dos Funcionários, 1540, Curitiba – Paraná Postal Code 80035-050, Brazil.

Tel./fax: 55(41)3350-5623;

e-mail: [email protected]

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First published: 18 November 2013
Citations: 6
Institution in which work was performed: National Primate Center, Evandro Chagas Institute, Ministry of Health, Ananindeua – Pará, Brazil.

Abstract

Background

Although commonly used, dissociative anesthesia results in unsatisfactory and long recovery periods. The intravenous anesthetic propofol seems to be the most advantageous solution. The objectives of this study were to investigate the required infusion rate of propofol to maintain surgical anesthesia and to compare it to tiletamine-zolazepam in Aotus infulatus.

Methods

Eight healthy feline night monkeys were anesthetized with propofol (PRO) or tiletamine-zolazepam (TZ) during 60 minutes. Cardiopulmonary parameters, arterial blood gases and lactate and quality and times to recovery were determined.

Results

Mean infusion rate of propofol was 0.53 ± 0.10 mg/kg/minute. Cardiopulmonary effects did not show marked differences between groups. Times for hanging, ventral recumbency, and normal ambulation were lower in PRO. Establishment of desirable anesthetic depth was easier, recovery quality was superior, and lactate levels were lower in PRO.

Conclusions

Compared with tiletamine-zolazepam, minor post-anesthetic adverse events should be expected with propofol anesthesia, as well as faster and better anesthetic recovery.

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