Trevor Hansen, Ameya Gangal, Eman Hijab, Devon Barrett, Howa Yeung and Yichun Cao have no conflicts of interest to declare. Jeffrey Switchenko discloses NIH P30, Award number: 2P30CA138292-09 as a funding source for biostatistical support through Winship Cancer Institute of Emory University. Travis W. Blalock discloses contract with Castle Biosciences, LLC, as PI for unrelated institutional study; payments to institution.

Funding source

This article has no direct funding source.

This work has not been previously published and is not submitted elsewhere.

IRB #: 00116635

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Abstract

Background

Incidence of surgical site infection (SSI) following Mohs micrographic surgery (MMS) amongst patients with diabetes is largely unknown.

Objective

Evaluate diabetes as a potential SSI risk factor in MMS by comparing SSI incidence in a cohort of patients with and without diabetes.

Methods

A 5-year retrospective review to determine SSI rate in patients with diabetes compared to patients without diabetes. SSI incidence in patients with diabetes was further compared by A1c, and the impact of antibiotics on SSI rate was also examined.

Results

Overall rate of SSI was 1.47% (53/3597 cases). SSI rate amongst patients with diabetes was 1.95% (14/719 cases) compared to 1.35% (39/2878 cases) in patients without diabetes, with a non-significant odds ratio for SSI of 1.45 (95% CI = 0.78–2.68, P = 0.241). Multivariable logistic regression analysis revealed no difference in SSI. Stratification of diabetic patients by A1c into ≥7.0 and <7.0 compared to patients without diabetes yielded no statistically significant difference in SSI amongst all groups (P = 0.815). Whether an antibiotic was prescribed did not significantly impact SSI rate between groups.

Conclusion

No significant difference in postoperative SSI was found in patients with diabetes compared to patients without diabetes following MMS regardless of degree of glycaemic control.

Open Research

Data Availability Statement

The data that support the findings are available upon request.

Supporting Information

References

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Citing Literature

Volume36, Issue6

June 2022

Pages 927-931

Filename	Description
jdv17986-sup-0001-TableS1.docxWord 2007 document , 19.3 KB	Table S1. Infectious organisms identified in post-surgical wound infection.
jdv17986-sup-0004-TableS4.docxWord 2007 document , 17.5 KB	Table S2. Body location of SSI by cohort.
jdv17986-sup-0002-TableS2.docxWord 2007 document , 21.1 KB	Table S3. Antibiotics prescribed on day of surgery.
jdv17986-sup-0003-TableS3.docxWord 2007 document , 17.6 KB	Table S4. Diagnosis treated with MMS.

Postoperative surgical site infection rate in patients with diabetes following Mohs micrographic surgery: a retrospective analysis

Abstract

Background

Objective

Methods

Results

Conclusion

Open Research

Data Availability Statement

Supporting Information

References

Citing Literature

References

Information

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Postoperative surgical site infection rate in patients with diabetes following Mohs micrographic surgery: a retrospective analysis

Abstract

Background

Objective

Methods

Results

Conclusion

Open Research

Data Availability Statement

Supporting Information

References

Citing Literature

References

Related

Information