CASE REPORT OR CASE SERIES
Long-term results of periodontal regenerative therapy: A retrospective practice-based cohort study
Frank Bröseler,
Christina Tietmann,
Ann-Katrin Hinz, Søren Jepsen,
Corresponding Author
Frank Bröseler
Private Practice for Periodontology, Aachen, Germany
Both authors contributed equally.Correspondence
Frank Bröseler, Private Practice for Periodontology, Aachen, Germany.
Email: [email protected]
Search for more papers by this authorChristina Tietmann
Private Practice for Periodontology, Aachen, Germany
Both authors contributed equally.Search for more papers by this authorSøren Jepsen
Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany
Search for more papers by this authorFrank Bröseler,
Christina Tietmann,
Ann-Katrin Hinz, Søren Jepsen,
Corresponding Author
Frank Bröseler
Private Practice for Periodontology, Aachen, Germany
Both authors contributed equally.Correspondence
Frank Bröseler, Private Practice for Periodontology, Aachen, Germany.
Email: [email protected]
Search for more papers by this authorChristina Tietmann
Private Practice for Periodontology, Aachen, Germany
Both authors contributed equally.Search for more papers by this authorSøren Jepsen
Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany
Search for more papers by this authorFunding information
The analysis by an independent statistician was supported by a grant from the company Geistlich, CH. The authors had full control of the data at all times. No other external funding, apart from the support of the authors′ institution, was available for this study.
Abstract
Aim
Evaluation of the long-term effectiveness of regenerative treatment of intra-bony defects in periodontal practice.
Material and Methods
A total of 1,008 intra-bony defects in 176 patients were analysed after using collagen-added deproteinized bovine bone mineral (DBBMc) with or without collagen membrane (CM) or enamel matrix derivative (EMD). Defects were classified as one- and two-wall and as shallow (≤6 mm), moderate (>6 and <11 mm) and deep (≥11 mm). Radiographic bone level changes were evaluated after 1 year, 2 to 4 years and 5 to 10 years.
Results
Mean radiographic defect fill was 3.8 mm after 1 year and remained stable up to 10 years. Deep and moderate defects showed a higher degree of fill than shallow defects (53.3%, 49.2%, 42.9%). Tooth loss amounted to 2.6%, was dependent on initial defect size (1.2% shallow, 1.4% moderate, 5.7% deep defects) and occurred mainly due to endodontic reasons.
Conclusions
Within the limits of the retrospective study design, the findings indicate that periodontal treatment using DBBMc with or without CM or EMD can lead to long-term defect reduction and tooth survival for up to 10 years in the setting of a periodontal practice.
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