Periodontal Therapy
In-office treatment for dentin hypersensitivity: a systematic review and network meta-analysis
Po-Yen Lin,
Ya-Wen Cheng,
Chia-Yi Chu,
Kuo-Liong Chien,
Chun-Pin Lin,
Yu-Kang Tu,
Po-Yen Lin
Department of Dentistry, School of Dentistry, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan
Department of Dentistry, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
Search for more papers by this authorYa-Wen Cheng
Department of Dentistry, School of Dentistry, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan
Search for more papers by this authorChia-Yi Chu
Department of Dentistry, School of Dentistry, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan
Department of Dentistry, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
Search for more papers by this authorKuo-Liong Chien
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
Search for more papers by this authorChun-Pin Lin
Department of Dentistry, School of Dentistry, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan
Search for more papers by this authorCorresponding Author
Yu-Kang Tu
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
Address:
Yu-Kang Tu
Institute of Epidemiology and Preventive Medicine
College of Public Health, National Taiwan University
Room 539, 17 Xu-Zhou Road
Taipei
Taiwan
E-mail: [email protected]
Search for more papers by this authorPo-Yen Lin,
Ya-Wen Cheng,
Chia-Yi Chu,
Kuo-Liong Chien,
Chun-Pin Lin,
Yu-Kang Tu,
Po-Yen Lin
Department of Dentistry, School of Dentistry, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan
Department of Dentistry, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
Search for more papers by this authorYa-Wen Cheng
Department of Dentistry, School of Dentistry, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan
Search for more papers by this authorChia-Yi Chu
Department of Dentistry, School of Dentistry, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan
Department of Dentistry, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
Search for more papers by this authorKuo-Liong Chien
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
Search for more papers by this authorChun-Pin Lin
Department of Dentistry, School of Dentistry, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan
Search for more papers by this authorCorresponding Author
Yu-Kang Tu
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
Address:
Yu-Kang Tu
Institute of Epidemiology and Preventive Medicine
College of Public Health, National Taiwan University
Room 539, 17 Xu-Zhou Road
Taipei
Taiwan
E-mail: [email protected]
Search for more papers by this authorConflict of interest and sources of funding statement
No external funding, apart from the support of the authors' institution, was available for this study. The authors declare that there are no conflicts of interest in this study.
Abstract
Aim
Dentin hypersensitivity, caused by the exposure and patency of dentinal tubules, can affect patients' quality of life. The aim of this study was to undertake a systematic review and a network meta-analysis, comparing the effectiveness in resolving dentin hypersensitivity among different in-office desensitizing treatments.
Materials and Methods
A literature search was performed with electronic databases and by hand until December 2011. The included trials were divided into six treatment groups as placebo, physical occlusion, chemical occlusion, nerve desensitization, laser therapy and combined treatments. The treatment effects between groups were estimated with standardized mean differences by using a Bayesian network meta-analysis.
Results
Forty studies were included. The standardized mean difference between placebo and physical occlusion was −2.57 [95% credible interval (CI): −4.24 to −0.94]; placebo versus chemical occlusion was −2.33 (95% CI: −3.65 to −1.04); placebo versus nerve desensitization was −1.72 (95% CI: −4.00 to 0.52); placebo versus laser therapy was −2.81 (95% CI: −4.41 to −1.24); placebo versus combined treatment was −3.47 (95% CI: −5.99 to −0.96). The comparisons of the five active treatments showed no significant differences.
Conclusions
The results from network meta-analysis showed that most active treatment options had significantly better treatment outcome than placebo.
Supporting Information
| Filename | Description |
|---|---|
| jcpe12011-sup-0001-AppendixS1.docxWord document, 63.7 KB | Appendix S1. Quality assessment of the included articles for network meta-analysis. |
| jcpe12011-sup-0002-AppendixS2.docxWord document, 13.4 KB | Appendix S2. Results of network and standard meta-analysis. |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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