Volume 35, Issue 11 pp. 2211-2219
ORIGINAL ARTICLE

The positive F wave in lead V1 of typical atrial flutter is caused by activation of the right atrial appendage: Insight from mapping during entrainment from the right atrial appendage

Shu Yamashita MD, PhD

Shu Yamashita MD, PhD

Department of Cardiology, NHO Disaster Medical Center, Tokyo, Japan

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Akira Mizukami MD, PhD

Corresponding Author

Akira Mizukami MD, PhD

Department of Cardiology, Kameda Medical Center, Chiba, Japan

Correspondence Akira Mizukami, MD, PhD, Department of Cardiology, Kameda Medical Center, Higashi-cho 929, Kamogawa City, Chiba 296-8602, Japan.

Email: [email protected]

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Maki Ono MD, PhD

Maki Ono MD, PhD

Department of Cardiology, Kameda Medical Center, Chiba, Japan

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Jiro Hiroki MD, PhD

Jiro Hiroki MD, PhD

Department of Cardiology, Kameda Medical Center, Chiba, Japan

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Shota Miyakuni MD, PhD

Shota Miyakuni MD, PhD

Department of Cardiology, Kameda Medical Center, Chiba, Japan

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Takumi Arashiro

Takumi Arashiro

Department of Medical Engineering, Kameda Medical Center, Chiba, Japan

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Daisuke Ueshima MD, PhD

Daisuke Ueshima MD, PhD

Department of Cardiology, Kameda Medical Center, Chiba, Japan

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Akihiko Matsumura MD

Akihiko Matsumura MD

Department of Cardiology, Kameda Medical Center, Chiba, Japan

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Shinsuke Miyazaki MD, PhD

Shinsuke Miyazaki MD, PhD

Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan

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Tetsuo Sasano MD, PhD

Tetsuo Sasano MD, PhD

Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan

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First published: 26 September 2024
Citations: 1

Disclosures: None.

Abstract

Introduction

Typical atrial flutter (AFL) is a macroreentrant tachycardia in which intracardiac conduction rotates counterclockwise around the tricuspid annulus. Typical AFL has specific electrocardiographic characteristics, including a negative sawtooth-like wave in the inferior lead and a positive F wave in lead V1. This study aimed to analyze the origin of the positive F wave in lead V1, which has not been completely understood.

Methods

This study enrolled 10 patients who underwent radiofrequency catheter ablation for a typical AFL. Electroanatomical mapping was performed both during typical AFL and entrainment from the right atrial appendage (RAA). The 12-lead electrocardiogram (ECG) and three-dimensional (3D) electroanatomical maps were analyzed.

Results

The positive F wave in lead V1 changed during entrainment from the RAA in all the cases. The 3D map during entrainment from the RAA revealed an area of antidromic capture around the RAA, which collided with the orthodromic wave in the anterior right atrium. This area of antidromic capture around the RAA was the only difference from the 3D electroanatomical map of AFL and is considered the cause of the change in the F wave in lead V1 during entrainment.

Conclusion

The analysis of the differences in the 12-lead ECG and 3D maps between tachycardia and entrainment from the RAA clearly demonstrated that activation around the RAA is responsible for the generation of the positive F wave in lead V1 of typical AFL.

CONFLICT OF INTEREST STATEMENT

The authors declare no conflict of interest.

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