REVIEW
Prevalence of co-occurring psychiatric disorders in adults and adolescents with intellectual disability: A systematic review and meta-analysis
Mario G. Mazza,
Aurora Rossetti,
Giovanna Crespi,
Massimo Clerici,
Corresponding Author
Mario G. Mazza
Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy
Correspondence
Mario G. Mazza, Department of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza (MB), Italy.
Email: [email protected]
Search for more papers by this authorAurora Rossetti
Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy
Search for more papers by this authorGiovanna Crespi
Psychiatric Department-ASST Monza, Monza, Italy
Search for more papers by this authorMassimo Clerici
Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy
Search for more papers by this authorMario G. Mazza,
Aurora Rossetti,
Giovanna Crespi,
Massimo Clerici,
Corresponding Author
Mario G. Mazza
Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy
Correspondence
Mario G. Mazza, Department of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza (MB), Italy.
Email: [email protected]
Search for more papers by this authorAurora Rossetti
Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy
Search for more papers by this authorGiovanna Crespi
Psychiatric Department-ASST Monza, Monza, Italy
Search for more papers by this authorMassimo Clerici
Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy
Search for more papers by this authorFunding information
This research received no specific grant from any funding agency, commercial or not-for-profit sectors.
Abstract
Background
Subjects with intellectual disability (ID) are vulnerable to experience psychiatric disorders. The present authors performed a systematic review and meta-analysis to estimate the prevalence of co-occurring psychiatric disorders, excluding co-occurring autism spectrum disorders, in subjects with intellectual disability.
Method
The present authors performed a random-effects meta-analysis of the prevalence of psychiatric disorders in adults and adolescents with intellectual disability.
Results
Twenty-two studies were included. The pooled prevalence of any co-occurring psychiatric disorders in intellectual disability was 33.6% (95% CI: 25.2%–43.1%) with high heterogeneity but no publication bias. Prevalence was lower in population-based studies, in studies that used ICD criteria for the psychopathology and in studies with low risk of bias. The prevalence was higher in mild, moderate and severe intellectual disability than in profound intellectual disability.
Conclusions
Psychiatric disorders are common in subjects with intellectual disability, and the present authors found that clinical and methodological moderators affect the pooled prevalence.
CONFLICT OF INTEREST
None.
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