Cavernous Carotid Pseudoaneurysm Following Transsphenoidal Surgery
Michael Fu BS
From the Yale University School of Medicine (MF); Department of Neurosurgery (TP, JMB, KRB); Department of Neurology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (JMB).
Search for more papers by this authorToral Patel MD
From the Yale University School of Medicine (MF); Department of Neurosurgery (TP, JMB, KRB); Department of Neurology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (JMB).
Search for more papers by this authorJoachim M. Baehring MD
From the Yale University School of Medicine (MF); Department of Neurosurgery (TP, JMB, KRB); Department of Neurology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (JMB).
Search for more papers by this authorKetan R. Bulsara MD
From the Yale University School of Medicine (MF); Department of Neurosurgery (TP, JMB, KRB); Department of Neurology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (JMB).
Search for more papers by this authorMichael Fu BS
From the Yale University School of Medicine (MF); Department of Neurosurgery (TP, JMB, KRB); Department of Neurology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (JMB).
Search for more papers by this authorToral Patel MD
From the Yale University School of Medicine (MF); Department of Neurosurgery (TP, JMB, KRB); Department of Neurology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (JMB).
Search for more papers by this authorJoachim M. Baehring MD
From the Yale University School of Medicine (MF); Department of Neurosurgery (TP, JMB, KRB); Department of Neurology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (JMB).
Search for more papers by this authorKetan R. Bulsara MD
From the Yale University School of Medicine (MF); Department of Neurosurgery (TP, JMB, KRB); Department of Neurology, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (JMB).
Search for more papers by this authorJ Neuroimaging 2013;23:319-325.
ABSTRACT
Pseudoaneurysm of the internal carotid artery (ICA) as a result of injury during transsphenoidal surgery is a rare but serious complication. We present a review of this subject, identifying 22 such cases in the literature, and contribute an unusual case of our own. Among our cohort, 23% of patients had no evidence of vascular injury or hemorrhage during the initial transsphenoidal operation, and presented at an average of 83 days after surgery. The average time to diagnosis for patients with intraoperative bleeding was 64 days after surgery. Epistaxis was the most common initial presenting symptom, seen in 41% of patients, and traditional angiography was employed in every case to make the diagnosis of pseudoaneurysm. Though complete occlusion of the ICA was ultimately required in 41% of patients, the remainder were treated with a variety of modalities. While intraoperative hemorrhage is certainly the most predictive indicator of iatrogenic vascular damage, in its absence, other signs such as postoperative bruits may be predictive of pseudoaneurysm formation as well. The continued accumulation of these unique cases will hopefully provide definitive recommendations on the early recognition and treatment of this serious condition, especially regarding the emerging role of endovascular therapy in its management.
Supporting Information
Cavernous Carotid Pseudoaneurysm Following Transsphenoidal Surgery
Filename | Description |
---|---|
JON_677_sm_Supmat.doc117 KB | Supporting info item |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
References
- 1 Ciric I, Ragin A, Baumgartner C, et al. Complications of transsphenoidal surgery: results of a national survey, review of the literature, and personal experience. Neurosurgery 1997; 40(2): 225–236 [discussion 236-227].
- 2 Oskouian RJ, Kelly DF, Laws ER, Jr. Vascular injury and transsphenoidal surgery. Front Horm Res 2006; 34: 256–278.
- 3 Laws ER, Jr. Vascular complications of transsphenoidal surgery. Pituitary 1999; 2(2): 163–170.
- 4 Ahuja A, Guterman LR, Hopkins LN. Carotid cavernous fistula and false aneurysm of the cavernous carotid artery: complications of transsphenoidal surgery. Neurosurgery 1992; 31(4): 774–778 [discussion 778-779].
- 5 Raymond J, Hardy J, Czepko R, et al. Arterial injuries in transsphenoidal surgery for pituitary adenoma; the role of angiography and endovascular treatment. AJNR Am J Neuroradiol 1997; 18(4): 655–665.
- 6 Reddy K, Lesiuk H, West M, et al. False aneurysm of the cavernous carotid artery: a complication of transsphenoidal surgery. Surg Neurol 1990; 33(2): 142–145.
- 7 Bergland RM, Ray BS, Torack RM. Anatomical variations in the pituitary gland and adjacent structures in 225 human autopsy cases. J Neurosurg 1968; 28(2): 93–99.
- 8 Ciceri EF, Regna-Gladin C, Erbetta A, et al. Iatrogenic intracranial pseudoaneurysms: neuroradiological and therapeutical considerations, including endovascular options. Neurol 2006; 27(5): 317–322.
- 9 Solheim O, Selbekk T, Lovstakken L, et al. Intrasellar ultrasound in transsphenoidal surgery: a novel technique. Neurosurgery 2010; 66(1): 173–185 [discussion 185-176].
- 10 Dusick JR, Esposito F, Malkasian D, et al. Avoidance of carotid artery injuries in transsphenoidal surgery with the Doppler probe and micro-hook blades. Neurosurgery 2007; 60(4 Suppl 2): 322–328 [discussion 328-329].
- 11 Cappabianca P, Cavallo LM, Colao A, de Divitiis E. Surgical complications associated with the endoscopic endonasal transsphenoidal approach for pituitary adenomas. J Neurosurg Aug 2002; 97(2): 293–298.
- 12 Pozzati E, Giuliani G, Poppi M, et al. Blunt traumatic carotid dissection with delayed symptoms. Stroke 1989; 20(3): 412–416.
- 13 Buerke B, Tombach B, Stoll W, et al. Magnetic resonance angiography follow-up examinations to detect iatrogenic pseudoaneurysms following otorhinolaryngological surgery. J Laryngol Otol 2007; 121(7): 698–701.
- 14 Chun JY, Smith W, Halbach VV, et al. Current multimodality management of infectious intracranial aneurysms. Neurosurgery 2001; 48(6): 1203–1213 [discussion 1213-1204].
- 15 Ducruet AF, Hickman ZL, Zacharia BE, et al. Intracranial infectious aneurysms: a comprehensive review. Neurosurg Rev ; 33(1): 37–46.
- 16 Okamura HO, Kamiyama R, Takiguchi Y, et al. Histopathological examination of ruptured carotid artery after irradiation. ORL J Otorhinolaryngol Relat Spec 2002; 64(3): 226–228.
- 17
Silverberg GD,
Britt RH,
Goffinet DR.
Radiation-induced carotid artery disease.
Cancer
1978; 41(1): 130–137.
10.1002/1097-0142(197801)41:1<130::AID-CNCR2820410121>3.0.CO;2-X CAS PubMed Web of Science® Google Scholar
- 18 Painter MJ, Chutorian AM, Hilal SK. Cerebrovasculopathy following irradiation in childhood. Neurology 1975; 25(2): 189–194.
- 19 Barami K, Grow A, Brem S, et al. Vascular after radiosurgery for meningiomas. Neurosurg Focus. 2007; 22(3): E9.
- 20 Buyukcam F, Sonmez FT, Aydin K. Successfully treated massive epistaxis in a patient with internal carotid artery pseudoaneurysm. J Craniofac Surg ; 21(4): 1304–1305.
- 21 Cheng KY, Lee KW, Chiang FY, et al. Rupture of radiation-induced internal carotid artery pseudoaneurysm in a patient with nasopharyngeal carcinoma—spontaneous occlusion of carotid artery due to long-term embolizing performance. Head Neck 2008; 30(8): 1132–1135.
- 22 Crowley RW, Dumont AS, Jane JA, Jr. Bilateral intracavernous carotid artery pseudoaneurysms as a result of sellar reconstruction during the transsphenoidal resection of a pituitary macroadenoma: case report. Minim Invasive Neurosurg 2009; 52(1): 44–48.
- 23 Struffert T, Buhk JH, Buchfelder M, et al. Coil migration after endovascular coil occlusion of internal carotid artery pseudoaneurysms within the sphenoid sinus. Minim Invasive Neurosurg 2009; 52(2): 89–92.
- 24 Lantos G, Fein JM, Knep S. Cortical artery aneurysm formation after extracranial to intracranial bypass surgery. Case report. J Neurosurg 1984; 60(3): 636–639.
- 25 Cosgrove GR, Villemure JG, Melancon D. Traumatic intracranial aneurysm due to arterial injury at surgery. Case report. J Neurosurg 1983; 58(2): 291–294.
- 26 Overton MC, 3rd, Calvin TH, Jr. Iatrogenic cerebral cortical aneurysm. Case report. J Neurosurg 1966; 24(3): 672–675.
- 27 Wakai S, Yoshimasu N, Eguchi T, et al. Traumatic intracavernous aneurysm of the internal carotid artery following surgery for chronic sinusitis. Surg Neurol 1980; 13(5): 391–394.
- 28 Kadyrov NA, Friedman JA, Nichols DA, et al. Endovascular treatment of an internal carotid artery pseudoaneurysm following transsphenoidal surgery. Case report. J Neurosurg 2002; 96(3): 624–627.
- 29 Vanninen RL, Manninen HI, Rinne J. Intrasellar latrogenic carotid pseudoaneurysm: endovascular treatment with a polytetrafluoroethylene-covered stent. Cardiovasc Intervent Radiol May-Jun2003; 26(3): 298–301.
- 30 Hattori I, Iwasaki K, Horikawa F, et al. Treatment of a ruptured giant internal carotid artery pseudoaneurysm following transsphenoidal surgery: case report and literature review. No Shinkei Geka 2006; 34(11): 1141–1146.
- 31 Medel R, Crowley RW, Hamilton DK, et al. Endovascular obliteration of an intracranial pseudoaneurysm: the utility of Onyx. J Neurosurg Pediatr 2009; 4(5): 445–448.
- 32 Eckert B, Thie A, Carvajal M, et al. Predicting hemodynamic ischemia by transcranial Doppler monitoring during therapeutic balloon occlusion of the internal carotid artery. AJNR Am J Neuroradiol 1998; 19(3): 577–582.
- 33 Saatci I, Cekirge HS, Ozturk MH, et al. Treatment of internal carotid artery aneurysms with a covered stent: experience in 24 patients with mid-term follow-up results. AJNR Am J Neuroradiol 2004; 25(10): 1742–1749.
- 34 Ahuja V, Tefera G. Successful covered stent-graft exclusion of carotid artery pseudo-aneurysm: two case reports and review of literature. Ann Vasc Surg 2007; 21(3): 367–372.
- 35 Leung GK, Auyeung KM, Lui WM, et al. Emergency placement of a self-expandable covered stent for carotid artery injury during trans-sphenoidal surgery. Br J Neurosurg 2006; 20(1): 55–57.
- 36 Li MH, Li YD, Gao BL, et al. A new covered stent designed for intracranial vasculature: application in the management of pseudoaneurysms of the cranial internal carotid artery. AJNR Am J Neuroradiol 2007; 28(8): 1579–1585.