In Vitro and In Vivo Assessment of an Intelligent Artificial Anal Sphincter in Rabbits
Corresponding Author
Zong-Hai Huang
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Prof. Zong-hai Huang Department of General Surgery, Zhujiang Hospital, Southern Medical University, 510282, Guangzhou, China. E-mail: [email protected]Search for more papers by this authorFu-Jun Shi
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorFei Chen
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorFei-Xue Liang
Institute of Biomedical Engineering, Southern Medical University, Guangzhou, China
Search for more papers by this authorQiang Li
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorJin-Long Yu
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorZhou Li
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorXin-Jun Han
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorCorresponding Author
Zong-Hai Huang
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Prof. Zong-hai Huang Department of General Surgery, Zhujiang Hospital, Southern Medical University, 510282, Guangzhou, China. E-mail: [email protected]Search for more papers by this authorFu-Jun Shi
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorFei Chen
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorFei-Xue Liang
Institute of Biomedical Engineering, Southern Medical University, Guangzhou, China
Search for more papers by this authorQiang Li
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorJin-Long Yu
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorZhou Li
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorXin-Jun Han
Department of General Surgery, Zhujiang Hospital, Southern Medical University
Search for more papers by this authorAbstract
Artificial sphincters have been developed for patients with fecal incontinence, but finding a way to make such sphincters more “intelligent” remains a problem. We assessed the function of a novel intelligent artificial anal sphincter (IAAS) in vitro and in vivo in rabbits. After the prosthesis was activated, rabbits were continent of feces during 81.4% of the activation time. The fecal detection unit provided 100% correct signals on stool in vitro and 65.7% in vivo. The results indicated that the IAAS could efficiently maintain continence and detect stool; however, the IAAS is still in the preliminary experimental stage and more work is needed to improve the system.
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