Pediatric Sweet Syndrome: Case Report and Literature Review
James Halpern M.R.C.P.,
Asad Salim M.R.C.P.,
James Halpern M.R.C.P.
Department of Dermatology, University Hospital of North Staffordshire, Stoke-on-Trent, United Kingdom
Search for more papers by this authorAsad Salim M.R.C.P.
Department of Dermatology, Mid Staffordshire General Hospitals NHS Trust, Stafford, United Kingdom
Search for more papers by this authorJames Halpern M.R.C.P.,
Asad Salim M.R.C.P.,
James Halpern M.R.C.P.
Department of Dermatology, University Hospital of North Staffordshire, Stoke-on-Trent, United Kingdom
Search for more papers by this authorAsad Salim M.R.C.P.
Department of Dermatology, Mid Staffordshire General Hospitals NHS Trust, Stafford, United Kingdom
Search for more papers by this authorAddress correspondence to James Halpern, Specialty Registrar in Dermatology, Dermatology Department, Central Outpatients Department, University Hospital of North Staffordshire, Hartshill Road, Stoke-on-Trent ST4 7PA, UK, or e-mail: [email protected].
Abstract
Abstract: We report on an 18-month-old boy with a typical presentation of Sweet syndrome following an upper respiratory tract illness. No evidence of hematologic malignancy was found and he was successfully treated with oral prednisolone. A comprehensive literature review has summarized the features of pediatric Sweet syndrome from 66 reported cases. Cases occurring under the age of 3 years had a male predominance and no association with malignancy, whereas cases over the age of 3 years had an equal sex distribution and were strongly associated with myeloid line hematologic malignancies. Identified complications were serious with an overall mortality of 9% rising to 40% with cardiovascular involvement.
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