Early View

Sunrise-related headache: case report

UH Ulas

Corresponding Author

UH Ulas

Gülhane Military Medical Academy, Neurology Department, Turkey, and

Umit Hidir Ulas, Gülhane Military Medical Academy, Neurology Department, Turkey. E-mail [email protected]Search for more papers by this author
A Korkmaz

A Korkmaz

Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, TX, USA

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O Karadas

O Karadas

Gülhane Military Medical Academy, Neurology Department, Turkey, and

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Z Odabasi

Z Odabasi

Gülhane Military Medical Academy, Neurology Department, Turkey, and

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RJ Reiter

RJ Reiter

Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, TX, USA

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Abstract

A male, 34 years of age, suffers from headaches, red and watery eyes. The headaches began in childhood; the frequency of headaches has increased over the years and in the last decade headaches have occurred on a daily basis. If he wakes up before sunrise he feels much better and free of a headache; however, once he continues to sleep during and after sunrise, he suffers from tiredness, headache and nervousness. On magnetic resonance imaging (MRI), benign neuroepithelial cysts or a chronic infarct area was reported at the junction of the left medio-lateral zone of hypothalamus. After repeated MRI examinations, it was decided that the lesion on the left medio-lateral zone of hypothalamus may have disrupted the pineal gland and changed melatonin secretion. It was decided to treat him with 3 mg melatonin daily before going to bed. After a week of treatment, the patient reported that he felt very fresh and was virtually free of headaches.

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