Myxoid dermatofibrosarcoma protuberans prominently involving subcutaneous tissue: Efficacy of molecular analysis
Corresponding Author
Takahiro Kiyohara
Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Correspondence: Takahiro Kiyohara, M.D., Ph.D., Department of Dermatology, University of Fukui, 23-3 Matsuokashimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan. Email: [email protected]Search for more papers by this authorSuguru Sato
Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Search for more papers by this authorMasato Yasuta
Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Search for more papers by this authorTadakazu Okoshi
Department of Molecular Pathology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Search for more papers by this authorNaohito Hatta
Division of Dermatology, Toyama Prefectural Central Hospital, Toyama, Japan
Search for more papers by this authorTakayuki Nojima
Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Uchinada, Japan
Search for more papers by this authorMasanobu Kumakiri
Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Search for more papers by this authorCorresponding Author
Takahiro Kiyohara
Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Correspondence: Takahiro Kiyohara, M.D., Ph.D., Department of Dermatology, University of Fukui, 23-3 Matsuokashimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan. Email: [email protected]Search for more papers by this authorSuguru Sato
Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Search for more papers by this authorMasato Yasuta
Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Search for more papers by this authorTadakazu Okoshi
Department of Molecular Pathology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Search for more papers by this authorNaohito Hatta
Division of Dermatology, Toyama Prefectural Central Hospital, Toyama, Japan
Search for more papers by this authorTakayuki Nojima
Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Uchinada, Japan
Search for more papers by this authorMasanobu Kumakiri
Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Search for more papers by this author
References
- 1Reimann JDR, Fletcher CDM. Myxoid dermatofibrosarcoma protuberans. Am J Surg Pathol 2007; 31: 1371–1377.
- 2Mentzel T, Schärer L, Kazakov DV, Michal M. Myxoid dermatofibrosarcoma protuberans: clinicopathologic, immunohistochemical, and molecular analysis of eight cases. Am J Dermatopathol 2007; 29: 443–448.
- 3Patel KU, Szabo SS, Hernandez VS, et al. Dermatofibrosarcoma protuberans COL1A1-PDGFB fusion is identified in virtually all dermatofibrosarcoma protuberans cases when investigated by newly developed multiplex reverse transcription polymerase chain reaction and fluorescence in situ hybridization assays. Hum Pathol 2008; 39: 184–193.
- 4Simon MP, Pedeutour F, Sirvent N, et al. Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma. Nat Genet 1997; 15: 95–98.
- 5Shimizu A, O'Brien KP, Sjӧblom T, et al. The dermatofibrosarcoma protuberans-associated collagen type 1α1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB. Cancer Res 1999; 59: 3719–3723.
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