Volume 27, Issue 5 e12956
LITERATURE REVIEW

COVID-19 and pregnancy: A scoping review on pregnancy characteristics and outcomes

Karoline Faria de Oliveira RN, PhD

Karoline Faria de Oliveira RN, PhD

Registered Nurse

Department of Nursing in Hospital Assistance, Federal University of Triângulo Mineiro, Uberaba, Brazil

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Jacqueline Faria de Oliveira RN, PhD

Jacqueline Faria de Oliveira RN, PhD

Registered Nurse

Hospital de Clínicas, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil

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Monika Wernet PhD

Monika Wernet PhD

Associate Professor

Department of Nursing, Federal University of Sāo Carlos, Sāo Paulo, Brazil

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Marina Carvalho Paschoini PhD

Marina Carvalho Paschoini PhD

Obstetrician, Adjunct Professor

Department of Gynecology and Obstetrics, Federal University of Triângulo Mineiro, Uberaba, Brazil

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Mariana Torreglosa Ruiz PhD

Corresponding Author

Mariana Torreglosa Ruiz PhD

Nurse-midwife, Adjunct Professor

Department of Nursing in Hospital Assistance, Federal University of Triângulo Mineiro, Uberaba, Brazil

Correspondence

Mariana Torreglosa Ruiz, Universidade Federal do Triângulo Mineiro, Praça Manoel Terra, 330, Centro, CEP 38025-015. Uberaba, Minas Gerais, Brazil.

Email: [email protected]

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First published: 16 May 2021
Citations: 4

Funding information: CNPq, Grant/Award Number: 141513/2020-3

Abstract

Aim

The study aim was to map clinical characteristics and the evolution of pregnancies in pregnant women with confirmed diagnosis of SARS-CoV-2 infection.

Methods

Searching four databases, studies were investigated that described the evolution of pregnancies in women diagnosed with SARS-CoV-2 infection through laboratory tests. A scoping review was undertaken, including 35 articles published in English. Two pairs of independent researchers synthesized the data.

Results

Most studies were case studies or case series and had a low risk of bias. A predominance of cases was found in women over the age of 30 years who got infected in the third term of pregnancy and who had comorbidities. The prematurity index varied with the heterogeneity of the samples, and the cases of abortion occurred in combination with severe forms of infection. Caesarean section deliveries predominated, indicated mainly by respiratory decompensation caused by infection. Most women were discharged.

Conclusion

Based on the reviewed studies, the profile and evolution of pregnant women infected with COVID-19 could be evaluated.

Summary statement

What is already known about this topic?

  • In 2020, the COVID-19 pandemic was decreed, currently accounting for more than 105 million cases and more than two million deaths.
  • Physiological changes of pregnancy predispose pregnant women to COVID-19 infection.
  • The characteristics of pregnancy associated with COVID-19 infection turn obstetric care into a constant challenge.

What this paper adds?

  • The review presents the profile of pregnant women infected by SARS-CoV-2, with laboratory confirmation using the diagnostic reference standard (PCR).
  • This review presents the profile of pregnant women infected with SARS-CoV-2 and the outcomes of the infection and pregnancy.

The implications of this paper:

  • Based on the knowledge of the profile, public policies can be planned to prevent and manage infection among pregnant and postpartum women.
  • Further studies are suggested, mainly follow-up studies of cohorts with pregnant women infected with SARS-CoV-2 to expand knowledge about the profile and obstetric outcomes.

CONFLICT OF INTEREST

The authors declare no conflict of interest.

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