Exploring psychological resilience and demoralisation in prostate cancer survivors
Corresponding Author
Ching Hui Chien
College of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan
Correspondence
Ching Hui Chien, College of Nursing, National Taipei University of Nursing and Health Sciences, No. 365, Ming-te Road, Peitou District. Taipei City 112, Taiwan.
Email: [email protected]
Search for more papers by this authorSee Tong Pang
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Search for more papers by this authorCheng Keng Chuang
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Search for more papers by this authorKuan Lin Liu
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Keelung, Keelung City, Taiwan
Search for more papers by this authorChun Te Wu
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Search for more papers by this authorKai Jie Yu
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei City, Taiwan
Search for more papers by this authorXuan Yi Huang
College of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan
Search for more papers by this authorPo Hung Lin
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Search for more papers by this authorCorresponding Author
Ching Hui Chien
College of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan
Correspondence
Ching Hui Chien, College of Nursing, National Taipei University of Nursing and Health Sciences, No. 365, Ming-te Road, Peitou District. Taipei City 112, Taiwan.
Email: [email protected]
Search for more papers by this authorSee Tong Pang
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Search for more papers by this authorCheng Keng Chuang
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Search for more papers by this authorKuan Lin Liu
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Keelung, Keelung City, Taiwan
Search for more papers by this authorChun Te Wu
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Search for more papers by this authorKai Jie Yu
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei City, Taiwan
Search for more papers by this authorXuan Yi Huang
College of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan
Search for more papers by this authorPo Hung Lin
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan City, Taiwan
Search for more papers by this authorFunding information: This work was supported by the National Science and Technology Council, Taipei City, Taiwan, R.O.C. (Grant NSTC 109–2314-B-227-007).
Abstract
Objective
This study aimed to investigate psychological resilience and demoralisation and their predictors and mediators in prostate cancer survivors (PCSs).
Methods
A cross-sectional research design was used. PCSs (N = 122; mean time since diagnosis = 54.79 months, range in 13 years and 2 months) were recruited using convenience sampling at the outpatient department of a hospital in Taiwan. Data collection was conducted using self-report structured questionnaires, including one for demographic and disease characteristics, the Expanded Prostate Cancer Index Composite, Cancer Survivors' Self-Efficacy Scale, Connor–Davidson Resilience Scale and the Demoralisation Scale.
Results
In PCSs, a lower most-recent level of prostate-specific antigen and higher cancer-specific self-efficacy were associated with better psychological resilience. Further, fewer hormonal, bowel and urinary symptoms and bother; higher cancer-specific self-efficacy; and better psychological resilience were associated with less demoralisation. Cancer-specific self-efficacy was a mediator for the relationship between urinary symptoms and bother and demoralisation, while psychological resilience mediated the relationship between cancer-specific self-efficacy and demoralisation.
Conclusions
The results reveal that cancer-specific self-efficacy is a protective factor against demoralisation and increases psychological resilience in PCSs. Better psychological resilience and fewer physical symptoms and bother are associated with less demoralisation in PCSs.
CONFLICT OF INTEREST
The authors declare no competing interests.
Open Research
DATA AVAILABILITY STATEMENT
The data used in this study are stored and managed by the corresponding author, Ching Hui Chien, to whom readers can direct any questions or need for data. The data are not publicly available due to the consideration of ethics, the researchers shall maintain the privacy of the participants and research data should be used only for academic articles.
REFERENCES
- An, E., Lo, C., Hales, S., Zimmermann, C., & Rodin, G. (2018). Demoralization and death anxiety in advanced cancer. Psycho-Oncology, 27(11), 2566–2572. https://doi.org/10.1002/pon.4843
- Arts-de Jong, M., DeJong, C. A. J., Hermens, R. P., Kissane, D. W., Massuger, L. M., Hoogerbrugge, N., Prins, J. B., & deHullu, J. A. (2018). High demoralization in a minority of oophorectomized BRCA1/2 mutation carriers influences quality of life. Journal of Psychosomatic Obstetrics and Gynecology, 39(2), 96–104. https://doi.org/10.1080/0167482x.2017.1296429
- Baker, H., Wellman, S., & Lavender, V. (2016). Functional quality-of-life outcomes reported by men treated for localized prostate cancer: A systematic literature review. Oncology Nursing Forum, 43(2), 199–218. https://doi.org/10.1188/16.ONF.199-218
- Bandura, A. (1977). Self-efficacy: Toward a unifying theory of behavioral change. Psychological Review, 84(2), 191–215. https://doi.org/10.1037//0033-295x.84.2.191
- Chien, C. H., Chuang, C. K., Liu, K. L., Wu, C. T., Pang, S. T., Tsay, P. K., Chang, Y. H., Huang, X. Y., & Liu, H. E. (2018). Effects of individual and partner factors on anxiety and depression in Taiwanese prostate cancer patients: A longitudinal study. European Journal of Cancer Care, 27(2), e12753. https://doi.org/10.1111/ecc.12753
- Chou, Y. J., Lin, H. Y., Cooper, B. A., Lin, B. R., Jiang, J. K., Yang, H. Y., Miaskowski, C., & Shun, S. C. (2022). A resilience model for patients with colorectal cancer: A structural equation modeling analysis. Cancer Nursing, 45(1), E83–e90. https://doi.org/10.1097/ncc.0000000000000882
- Clarke, D. M., & Kissane, D. W. (2002). Demoralization: Its phenomenology and importance. The Australian and New Zealand Journal of Psychiatry, 36(6), 733–742. https://doi.org/10.1046/j.1440-1614.2002.01086.x
- Connor, K. M., & Davidson, J. R. (2003). Development of a new resilience scale: The Connor-Davidson Resilience Scale (CD-RISC). Depression and Anxiety, 18(2), 76–82. https://doi.org/10.1002/da.10113
- Curtis, R., Groarke, A., & Sullivan, F. (2014). Stress and self-efficacy predict psychological adjustment at diagnosis of prostate cancer. Scientific Reports, 4, 5569. https://doi.org/10.1038/srep05569
- Faul, F., Erdfelder, E., Buchner, A., & Lang, A. G. (2009). Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses. Behavior Research Methods, 41(4), 1149–1160. https://doi.org/10.3758/brm.41.4.1149
- Foster, C., Breckons, M., Cotterell, P., Barbosa, D., Calman, L., Corner, J., Fenlon, D., Foster, R., Grimmett, C., Richardson, A., & Smith, P. W. (2015). Cancer survivors' self-efficacy to self-manage in the year following primary treatment. Journal of Cancer Survivorship, 9(1), 11–19. https://doi.org/10.1007/s11764-014-0384-0
- Foster, C., Breckons, M., Hankins, M., Fenlon, D., & Cotterell, P. (2013). Developing a scale to measure self-efficacy to SELF-manage problems following cancer treatment. Psycho-Oncology, 22(Supp. 1), 16. https://doi.org/10.10002/pon.3239
10.10002/pon.3239 Google Scholar
- Foster, C., & Fenlon, D. (2011). Recovery and self-management support following primary cancer treatment. British Journal of Cancer, 105(Suppl 1), S21–S28. https://doi.org/10.1038/bjc.2011.419
- Global Burden of Disease Cancer Collaboration. (2019). Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncology, 5(12), 1749–1768. https://doi.org/10.1001/jamaoncol.2019.2996
- Hayes, A. F. (2018). Introduction to mediation, moderation, and conditional process analysis: A regression-based approach ( 2nd ed.). The Guilford Press.
- Hung, H. C., Chen, H. W., Chang, Y. F., Yang, Y. C., Liu, C. L., Hsieh, R. K., Leu, Y. S., Chen, Y. J., Wang, T. E., Tsai, L. Y., Liu, S. I., & Fang, C. K. (2010). Evaluation of the reliability and validity of the Mandarin version of demoralization scale for cancer patients. Journal of Internal Medicine of Taiwan, 21, 427–435.
- Ignatius, J., & Garza, R. D. L. II (2019). Frequency of demoralization and depression in cancer patients. General Hospital Psychiatry, 60, 137–140. https://doi.org/10.1016/j.genhosppsych.2019.04.013
- Kissane, D. W., Wein, S., Love, A., Lee, X. Q., Kee, P. L., & Clarke, D. M. (2004). The Demoralization Scale: A report of its development and preliminary validation. Journal of Palliative Care, 20(4), 269–276. https://doi.org/10.1177/082585970402000402
- Lepore, S. J., & Revenson, T. (2006). Resilience and posttraumatic growth: Recovery, resistance, and reconfiguration. In C. Tedeschi (Ed.), Posttraumatic growth: Research and practice. Lawrence Erlbaum Associates.
- Liu, K. L., Chuang, C. K., Pang, S. T., Wu, C. T., Yu, K. J., Tsai, S. C., & Chien, C. H. (2021). Emotional state and cancer-related self-efficacy as affecting resilience and quality of life in kidney cancer patients: A cross-sectional study. Supportive Care in Cancer, 30, 2263–2271. https://doi.org/10.1007/s00520-021-06644-5
- Loprinzi, C. E., Prasad, K., Schroeder, D. R., & Sood, A. (2011). Stress Management and Resilience Training (SMART) program to decrease stress and enhance resilience among breast cancer survivors: A pilot randomized clinical trial. Clinical Breast Cancer, 11(6), 364–368. https://doi.org/10.1016/j.clbc.2011.06.008
- Lorig, K. R., & Holman, H. (2003). Self-management education: History, definition, outcomes, and mechanisms. Annals of Behavioral Medicine, 26(1), 1–7. https://doi.org/10.1207/s15324796abm2601_01
- Michel Bolla, M., & van Poppel, H. (2017). Management of prostate cancer: A multidisciplinary approach ( 2nd ed.). Springer. https://doi.org/10.1007/978-3-319-42769-0
10.1007/978-3-319-42769-0 Google Scholar
- Nanni, M. G., Caruso, R., Travado, L., Ventura, C., Palma, A., Berardi, A. M., Meggiolaro, E., Ruffilli, F., Martins, C., Kissane, D., & Grassi, L. (2018). Relationship of demoralization with anxiety, depression, and quality of life: A southern European study of Italian and Portuguese cancer patients. Psycho-Oncology, 27(11), 2616–2622. https://doi.org/10.1002/pon.4824
- Ni, M. Y., Li, T. K., Yu, N. X., Pang, H., Chan, B. H., Leung, G. M., & Stewart, S. M. (2016). Normative data and psychometric properties of the Connor-Davidson Resilience Scale (CD-RISC) and the abbreviated version (CD-RISC2) among the general population in Hong Kong. Quality of Life Research, 25(1), 111–116. https://doi.org/10.1007/s11136-015-1072-x
- Orom, H., Nelson, C. J., Underwood, W. III, Homish, D. L., & Kapoor, D. A. (2015). Factors associated with emotional distress in newly diagnosed prostate cancer patients. Psycho-Oncology, 24(11), 1416–1422. https://doi.org/10.1002/pon.3751
- Reb, A., Ruel, N., Fakih, M., Lai, L., Salgia, R., Ferrell, B., Sampath, S., Kim, J. Y., Raz, D. J., & Sun, V. (2017). Empowering survivors after colorectal and lung cancer treatment: Pilot study of a self-management survivorship care planning intervention. European Journal of Oncology Nursing, 29, 125–134. https://doi.org/10.1016/j.ejon.2017.06.003
- Richardson, G. E. (2002). The metatheory of resilience and resiliency. Journal of Clinical Psychology, 58(3), 307–321. https://doi.org/10.1002/jclp.10020
- Robinson, S., Kissane, D. W., Brooker, J., & Burney, S. (2015). A systematic review of the demoralization syndrome in individuals with progressive disease and cancer: A decade of research. Journal of Pain and Symptom Management, 49(3), 595–610. https://doi.org/10.1016/j.jpainsymman.2014.07.008
- Scandurra, C., Mangiapia, F., La Rocca, R., Di Bello, F., De Lucia, N., Muzii, B., Cantone, M., Zampi, R., Califano, G., Maldonato, N. M., & Longo, N. (2022). A cross-sectional study on demoralization in prostate cancer patients: The role of masculine self-esteem, depression, and resilience. Supportive Care in Cancer, 30(8), 7021–7030. https://doi.org/10.1007/s00520-022-07145-9
- Sharpley, C. F., Bitsika, V., Christie, D. R. H., Bradford, R., Steigler, A., & Denham, J. W. (2017). Psychological resilience aspects that mediate the depressive effects of urinary incontinence in prostate cancer survivors 10 years after treatment with radiation and hormone ablation. Journal of Psychosocial Oncology, 35(4), 438–450. https://doi.org/10.1080/07347332.2017.1306733
- Sharpley, C. F., Bitsika, V., Wootten, A. C., & Christie, D. R. (2014). Does resilience “buffer” against depression in prostate cancer patients? A multi-site replication study. European Journal of Cancer Care, 23(4), 545–552. https://doi.org/10.1111/ecc.12170
- Sharpley, C. F., Christie, D. R. H., & Bitsika, V. (2020). “Steeling” effects in the association between psychological resilience and cancer treatment in prostate cancer patients. Psycho-Oncology, 30, 67–73. https://doi.org/10.1002/pon.5537
- Sharpley, C. F., Christie, D. R. H., Bitsika, V., Andronicos, N. M., Agnew, L. L., Richards, T. M., & McMillan, M. E. (2018). Comparing a genetic and a psychological factor as correlates of anxiety, depression, and chronic stress in men with prostate cancer. Supportive Care in Cancer, 26(9), 3195–3200. https://doi.org/10.1007/s00520-018-4183-4
- Siegel, R. L., Miller, K. D., & Jemal, A. (2019). Cancer statistics, 2019. A Cancer Journal for Clinicians, 69(1), 7–34. https://doi.org/10.3322/caac.21551
- Taiwan Centers for Disease Control. (2022). Attention COVID-19. http://www.cdc.gov.tw/En
- Tang, P. L., Wang, H. H., & Chou, F. H. (2015). A systematic review and meta-analysis of demoralization and depression in patients with cancer. Psychosomatics, 56(6), 634–643. https://doi.org/10.1016/j.psym.2015.06.005
- van den Broeck, T., van den Bergh, R. C. N., Arfi, N., Gross, T., Moris, L., Briers, E., … Mottet, N. (2019). Prognostic value of biochemical recurrence following treatment with curative intent for prostate cancer: A systematic review. European Urology, 75(6), 967–987. https://doi.org/10.1016/j.eururo.2018.10.011
- Wei, J. T., Dunn, R. L., Litwin, M. S., Sandler, H. M., & Sanda, M. G. (2000). Development and validation of the expanded prostate cancer index composite (EPIC) for comprehensive assessment of health-related quality of life in men with prostate cancer. Urology, 56(6), 899–905. https://doi.org/10.1016/S0090-4295(00)00858-X
- Wu, X., Xu, H., Zhang, X., Han, S., Ge, L., Li, X., & Zhang, X. (2021). Self-efficacy, hope as mediators between positive coping and resilience among patients with gastric cancer before the first chemotherapy. Cancer Nursing, 44, 79–85. https://doi.org/10.1097/ncc.0000000000000753
- Xiong, J., Lipsitz, O., Nasri, F., Lui, L. M. W., Gill, H., Phan, L., Chen-Li, D., Iacobucci, M., Ho, R., Majeed, A., & McIntyre, R. S. (2020). Impact of COVID-19 pandemic on mental health in the general population: A systematic review. Journal of Affective Disorders, 277, 55–64. https://doi.org/10.1016/j.jad.2020.08.001
- Zhang, P., Mo, L., Torres, J., & Huang, X. (2019). Effects of cognitive behavioral therapy on psychological adjustment in Chinese pediatric cancer patients receiving chemotherapy: A randomized trial. Medicine (Baltimore), 98(27), e16319. https://doi.org/10.1097/md.0000000000016319
- Zhao, X., Sun, M., & Yang, Y. (2021). Effects of social support, hope and resilience on depressive symptoms within 18 months after diagnosis of prostate cancer. Health and Quality of Life Outcomes, 19(1), 15. https://doi.org/10.1186/s12955-020-01660-1