Volume 29, Issue 5 pp. 325-329
Therapeutic Hotline

Granuloma faciale successfully treated with ingenol mebutate

I. Bobyr

I. Bobyr

Department of Clinical and Molecular Sciences, Dermatological Unit and

I. Bobyr and A. Campanati have equally contributed to the manuscript.

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A. Campanati

A. Campanati

Department of Clinical and Molecular Sciences, Dermatological Unit and

I. Bobyr and A. Campanati have equally contributed to the manuscript.

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V. Consales

Corresponding Author

V. Consales

Department of Clinical and Molecular Sciences, Dermatological Unit and

Address correspondence and reprint requests to: Veronica Consales, MD, Department of Clinical and Molecular Sciences, Dermatological Unit, Polytechnic Marche University, via Conca 71, 60126 Ancona, Italy, or email: [email protected].Search for more papers by this author
M Giangiacomi

M Giangiacomi

Institute of Pathological Anatomy and Histopathology, Polytechnic Marche University, Ancona, Italy

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F. Diotallevi

F. Diotallevi

Department of Clinical and Molecular Sciences, Dermatological Unit and

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A. Offidani

A. Offidani

Department of Clinical and Molecular Sciences, Dermatological Unit and

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First published: 30 June 2016
Citations: 5

ABSTRACT

Granuloma faciale (GF) is a rare chronic inflammatory dermatosis of unknown etiology, characterized by leukocitoclastic vasculitis usually occurring on the face. We report a case of 60-years-old man with 3 year history of multiple actinic keratoses (AK) and persistent asymptomatic erythematous papules and plaques located over his left temporal region and the cheek: histopathology was consistent with GF. Herein we describe the successful treatment of the lesion with ingenol mebutate 0.015% gel focusing on the clinical, dermoscopic and histopathological findings of GF both before and after treatment.

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