Volume 48, Issue 12 pp. 1493-1496
CASE REPORT

Melanoma mimicking atypical fibroxanthoma: Report of an unusual case

Yanqing Wang MD

Yanqing Wang MD

Ackerman Academy of Dermatopathology, New York, New York, USA

Department of Dermatology, The Second Hospital of Shanxi Medical University, Taiyuan, China

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Ying Guo MD

Corresponding Author

Ying Guo MD

Ackerman Academy of Dermatopathology, New York, New York, USA

Correspondence

Ying Guo, MD, Ackerman Academy of Dermatopathology, 145 East 32nd Street, 10th Floor, New York, NY 10016.

Email: [email protected]

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First published: 13 July 2021
Citations: 1

Abstract

Melanoma may mimic a variety of skin lesions clinically and histopathologically, and presents diagnostic challenges. In this article, we describe a case of melanoma in an 89-year-old man with a very rare histopathologic presentation, namely the presence of pleomorphic and multinucleated giant cells with abundant cytoplasm, highly resembling an atypical fibroxanthoma. The differential diagnoses in conjunction with the findings in immunohistochemical study are also discussed.

DATA AVAILABILITY STATEMENT

Data sharing is not applicable to this article as no new data were created or analyzed in this study.

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