On the Association between Human Papillomavirus Vaccine and Primary Ovarian Failure
Paolo Pellegrino
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
These authors contributed equally to this work.Search for more papers by this authorCarla Carnovale
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
These authors contributed equally to this work.Search for more papers by this authorValentina Perrone
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this authorDionigi Salvati
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this authorMarta Gentili
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this authorTatiana Brusadelli
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this authorStefania Antoniazzi
IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
Search for more papers by this authorCorresponding Author
Emilio Clementi
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Scientific Institute, IRCCS E. Medea, Lecco, Italy
Correspondence
Emilio Clementi, Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, 20157 Milan, Italy.
E-mail: [email protected]
Search for more papers by this authorSonia Radice
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this authorPaolo Pellegrino
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
These authors contributed equally to this work.Search for more papers by this authorCarla Carnovale
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
These authors contributed equally to this work.Search for more papers by this authorValentina Perrone
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this authorDionigi Salvati
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this authorMarta Gentili
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this authorTatiana Brusadelli
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this authorStefania Antoniazzi
IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
Search for more papers by this authorCorresponding Author
Emilio Clementi
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Scientific Institute, IRCCS E. Medea, Lecco, Italy
Correspondence
Emilio Clementi, Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, 20157 Milan, Italy.
E-mail: [email protected]
Search for more papers by this authorSonia Radice
Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital “Luigi Sacco”, Università di Milano, Milan, Italy
Search for more papers by this author
References
- 1Colafrancesco S, Perricone C, Tomljenovic L, Shoenfeld Y: Human papilloma virus vaccine and primary ovarian failure: another facet of the autoimmune/inflammatory syndrome induced by adjuvants. Am J Reprod Immunol 2013; 70: 309–316.
- 2Little DT, Ward HR: Premature ovarian failure 3 years after menarche in a 16-year-old girl following human papillomavirus vaccination. BMJ Case Rep 2012; 2012. doi: 10.1136/bcr-2012-006879.
- 3Siegrist CA, Lewis EM, Eskola J, Evans SJ, Black SB: Human papilloma virus immunization in adolescent and young adults: a cohort study to illustrate what events might be mistaken for adverse reactions. Pediatr Infect Dis J 2007; 26: 979–984.
- 4Pellegrino P, Carnovale C, Perrone V, Antoniazzi S, Pozzi M, Clementi E, Radice S: Can HPV immunisation cause ADEM? Two case reports and literature review. Mult Scler 2013 [Epub ahead of print].
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