The impact of vitamin B metabolic disorders on hemodialysis (HD) patients' survival is unknown. This study is to investigate the association of serum vitamin B1, B3, B5, and B6 with all-cause and cardiovascular (CV) mortality in HD patients.

Methods

Patients' baseline serum vitamin B1, B3, B5, and B6 levels were collected, and they were followed up for the occurrence of all-cause and CV death. Kaplan–Meier analysis and Cox proportional hazards model were used to examine the association of vitamin B with mortality.

Results

Seventy-six HD patients were included. The median follow-up time was 99 months. Kaplan–Meier analysis showed that baseline vitamin B5 < 69.0 nmol/L and vitamin B6 < 8.1 ng/ml were associated with a higher risk of CV mortality, but these associations were nullified after adjustment.

Conclusions

Serum vitamins B1, B3, B5, and B6 were not associated with all-cause or CV mortality in HD patients.

Clinical Trial Registry: ChiCTR2200057078 (Chinese Clinical Trial Registry, https://www.chictr.org.cn/).

CONFLICT OF INTEREST

The authors declare that they have no conflict of interest.

Open Research

DATA AVAILABILITY STATEMENT

The datasets used during the current study are available from the corresponding author on reasonable request.

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Volume27, Issue3

June 2023

Pages 571-579

There is no association of serum vitamin B levels with all-cause and cardiovascular mortality in hemodialysis patients

Abstract

Introduction

Methods

Results

Conclusions

CONFLICT OF INTEREST

Open Research

DATA AVAILABILITY STATEMENT

REFERENCES

References

Information

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There is no association of serum vitamin B levels with all-cause and cardiovascular mortality in hemodialysis patients

Abstract

Introduction

Methods

Results

Conclusions

CONFLICT OF INTEREST

Open Research

DATA AVAILABILITY STATEMENT

REFERENCES

References

Related

Information